Zobrazeno 1 - 10
of 55
pro vyhledávání: '"J. Calaycay"'
Autor:
John L. Ho, Susan C. Nicholson, Carl Nathan, C. Linhares, J. R. Lapa e Silva, Jiayuan Geng, J. R. Weidner, W. Rom, J. Calaycay, R. Mumford, M. Da Gloria Bonecini-Almeida, Qiao-wen Xie, N. Boechat
Publikováno v:
The Journal of Experimental Medicine
The high-output pathway of nitric oxide production helps protect mice from infection by several pathogens, including Mycobacterium tuberculosis. However, based on studies of cells cultured from blood, it is controversial whether human mononuclear pha
Publikováno v:
Biochemistry. 39(11)
JNK3 alpha 1 is predominantly a neuronal specific MAP kinase that is believed to require, like all MAP kinases, both threonine and tyrosine phosphorylation for maximal enzyme activity. In this study we investigated the in vitro activation of JNK3 alp
Autor:
T J, Sewell, E, Lam, M M, Martin, J, Leszyk, J, Weidner, J, Calaycay, P, Griffin, H, Williams, S, Hung, J, Cryan
Publikováno v:
The Journal of biological chemistry. 269(33)
FK-506, a potent immunosuppressive drug, acts during the commitment phase of T-lymphocyte activation to block a subset of calcium-associated events necessary for transcription of certain early lymphokine genes. The drug binds to an abundant, cytosoli
Autor:
G, Wiederrecht, S, Hung, H K, Chan, A, Marcy, M, Martin, J, Calaycay, D, Boulton, N, Sigal, R L, Kincaid, J J, Siekierka
Publikováno v:
The Journal of biological chemistry. 267(30)
The immunoregulant FK-506 potently inhibits particular calcium-associated signal transduction events that occur early during T-lymphocyte activation and during IgE receptor-mediated exocytosis in mast cells. FK-506 binds to a growing family of recept
Publikováno v:
The Journal of Experimental Medicine
A central issue in nitric oxide (NO) research is to understand how NO can act in some settings as a servoregulator and in others as a cytotoxin. To answer this, we have sought a molecular basis for the differential regulation of the two known types o
Publikováno v:
The Biochemical journal. 274
Fibronectins are a class of cell-adhesion proteins produced from a single gene. The soluble plasma form is synthesized by hepatocytes and the insoluble cellular form by fibroblasts and other cell types. The proteins possess multiple binding domains f
Publikováno v:
Analytical biochemistry. 192(1)
We describe the construction of an improved, compact protein sequencer with a vertical flow path and continuous flow reactor (CFR). Unique features include a hexagonal valve for six fluid inputs to the CFR, which connects vertically to a transfer val
Publikováno v:
Journal of Biological Chemistry. 260:2301-2306
The complete amino acid sequence of a DNA-binding domain isolated from human plasma fibronectin after limited trypsin digestion has been obtained. It contains 132 amino acids and one biantennary glycosyl unit at residue 104, for an estimated Mr of 16
Autor:
Terry D. Lee, Annalisa Siri, John E. Shively, H Pande, Luciano Zardi, J Calaycay, Laura Borsi
Publikováno v:
Journal of Biological Chemistry. 260:12136-12141
The complete amino acid sequence of a DNA- and heparin-binding domain isolated by limited thermolysin digestion of human plasma fibronectin has been obtained. The domain contains 90 amino acids with a calculated molecular weight of 10,225. The appare
Publikováno v:
Thrombosis Research. 43:469-477
Two subtilisin-generated fragments of human plasma fibronectin exhibit significantly different gelatin affinities. One fragment of 60 kdaltons elutes from gelatin-Sepharose, after intact fibronectin, with pH 5.5, 50 mM citrate, 0.1 M NaCl. A 40 kdalt