Výsledky vyhledávání - "J. C. Wickens"

Wound tensile strength and contraction rate are not affected by laparotomy or pneumoperitoneum

Autor: John D. Allendorf, Richard L. Whelan, A. McKee, N. R. Gleason, K. Panageas, Ser Yee Lee, E. Buxton, Joseph Donahue, Marc Bessler, J. C. Wickens

Publikováno v: Surgical Endoscopy. 12:1166-1170

Many cellular elements responsible for wound healing are affected by laparotomy. The aim of this study was to evaluate the effects of laparotomy and CO2 pneumoperitoneum on wound healing.Male Sprague Dawley rats were randomly assigned to one of three

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e9d89f25b026f27cab50009a8754195
https://doi.org/10.1007/s004649900808

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Romazarit. A potential disease-modifying antirheumatic drug

Autor: D Bradshaw, C R Self, J C Wickens, D. P. Bloxham, Peter James Machin, C H Cashin, B P Tong, W E Barber, C E Smithen, John Mervyn Osbond

Publikováno v: Journal of Medicinal Chemistry. 34:772-777

The synthesis of a series of substituted heterocyclic alkoxypropionic acids is described. They were evaluated for antiinflammatory effects in two animal models of chronic inflammation; adjuvant arthritis and type II collagen arthritis in the rat. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25dbaf20a951916425ef40322324f05e
https://doi.org/10.1021/jm00106a044

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710. Chemical constitution and amœbicidal action. Part IV. Synthesis of emetine and stereoisomers of emetine

Autor: J. C. Wickens, J. M. Osbond, M. Barash

Publikováno v: J. Chem. Soc.. :3530-3543

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e56847677197eaa61abcca2f949e7dc5
https://doi.org/10.1039/jr9590003530

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542. Essential fatty acids. Part I. Synthesis of linoleic, γ-linolenic, arachidonic, and docosa-4,7,10,13,16-pentaenoic acid

Autor: J. M. Osbond, P. G. Philpott, J. C. Wickens

Publikováno v: J. Chem. Soc.. :2779-2787

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d72290859bc8ffc31a285d6eebd0d532
https://doi.org/10.1039/jr9610002779

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727. Chemical constitution and amœbicidal action. Part V. Stereochemistry of emetine

Autor: P. Plattner, A. Cohen, J. C. Wickens, O. Schnider, J. M. Osbond, A. Brossi

Publikováno v: J. Chem. Soc.. :3630-3632

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1777f349b46845094919c066272a9910
https://doi.org/10.1039/jr9590003630

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Bufuralol, a new beta-adrenoceptor blocking agent. Part 1: synthesis and structure-activity studies in a series of benzofuran-2-ethanolamines

Autor: G A, Fothergill, J M, Osbond, J C, Wickens

Publikováno v: Arzneimittel-Forschung. 27(5)

The synthesis and resolution of a new beta-adrenoceptor blocking agent, 1-(7-ethylbenzofuran-2-yl)-2-tert.-butylamino-1-hydroxyethane (bufuralol) are described. Structure-activity studies leading to selection of the title compound are discussed.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ba00c3e6292cc2a52a34e7b373a4a9eb
https://pubmed.ncbi.nlm.nih.gov/18158

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