Zobrazeno 1 - 10
of 21
pro vyhledávání: '"J. C. Troncoso"'
Autor:
J G, Shake, E A, Peck, E, Marban, V L, Gott, M V, Johnston, J C, Troncoso, J M, Redmond, W A, Baumgartner
Publikováno v:
The Annals of thoracic surgery. 72(6)
Ischemic preconditioning is an endogenous mechanism whereby brief periods of ischemia render neurons resistant to subsequent lethal insults. This protection appears to alter cellular apoptosis and can be induced by potassium channel openers acting on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8faafba2f2c04ac6b4543fd376427a2d
https://pubmed.ncbi.nlm.nih.gov/12173872
https://pubmed.ncbi.nlm.nih.gov/12173872
Publikováno v:
Annals of neurology. 46(3)
Perturbations in the microtubule-associated protein tau occur in several human neurodegenerative diseases. In Alzheimer's disease and progressive supranuclear palsy (PSP), tau proteins assemble into straight and paired helical filaments that form int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f95ec87e5de13349e0e43f2e78fee055
https://pubmed.ncbi.nlm.nih.gov/10482263
https://pubmed.ncbi.nlm.nih.gov/10482263
Publikováno v:
Journal of microscopy. 191(Pt 3)
Neurofilaments are cytoskeletal components of neurones that are thought to play an important structural role in the axon. Specific functions of neurofilaments are not yet well defined; however, other intermediate filaments are known to have structura
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::48cb7b86ad0db37c92821fa4f24e9fe2
https://pubmed.ncbi.nlm.nih.gov/9755496
https://pubmed.ncbi.nlm.nih.gov/9755496
Autor:
E E, Tseng, M V, Brock, M S, Lange, J C, Troncoso, M E, Blue, C J, Lowenstein, M V, Johnston, W A, Baumgartner
Publikováno v:
Surgery. 124(2)
Prolonged hypothermic circulatory arrest (HCA) causes clinical neurologic injury. This injury involves neuronal apoptosis, or programmed cell death. We have previously demonstrated that HCA causes glutamate excitotoxicity, increased nitric oxide (NO)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3c61181653c0dc4d2484740c33c27c48
https://pubmed.ncbi.nlm.nih.gov/9706152
https://pubmed.ncbi.nlm.nih.gov/9706152
Publikováno v:
Journal of cardiac surgery. 12
Central nervous system dysfunction continues to represent significant morbidity and associated mortality in patients undergoing cardiac surgery. Neurological dysfunction is most exaggerated in patients undergoing hypothermic circulatory arrest (HCA).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ee4c068c79fde6c540ef53e742cbf1a4
https://pubmed.ncbi.nlm.nih.gov/9271760
https://pubmed.ncbi.nlm.nih.gov/9271760
Publikováno v:
Connections, Cognition and Alzheimer’s Disease ISBN: 9783642645044
The hypothesis that Alzheimer’s disease is accelerated aging has been tested by comparing the patterns of neuron loss in the hippocampal region associated with normal aging and with Alzheimer’s disease. Qualitative differences were found in the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a48e0835a3fccf76a1cf8599e73128ad
https://doi.org/10.1007/978-3-642-60680-9_10
https://doi.org/10.1007/978-3-642-60680-9_10
Publikováno v:
Ugeskrift for laeger. 157(22)
The causal relationship between the neurodegenerative changes that accompany normal ageing and those that characterize Alzheimer's disease is unclear. The high incidence of Alzheimer's disease associated with old age and the presence of its neuropath
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::73e766c2c6e164976f1d29c0ee5c7107
https://pubmed.ncbi.nlm.nih.gov/7770982
https://pubmed.ncbi.nlm.nih.gov/7770982
Publikováno v:
Neurology. 45(4)
A 47-year-old white man with dementia, supranuclear ophthalmoplegia, and myoclonic ocular and facial jerks died in 1931. The case report in 1936 by Ford and Walsh diagnosed encephalitis. In 1993, we made a clinical diagnosis of Whipple's disease on t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d62ef83f0c0c221de2ced98e2c6dc88
https://pubmed.ncbi.nlm.nih.gov/7536902
https://pubmed.ncbi.nlm.nih.gov/7536902
Autor:
J M, Redmond, A M, Gillinov, K J, Zehr, M E, Blue, J C, Troncoso, B A, Reitz, D E, Cameron, M V, Johnston, W A, Baumgartner
Publikováno v:
The Journal of thoracic and cardiovascular surgery. 107(3)
Glutamate, the major central nervous system neurotransmitter, may have potent neurotoxic activity under conditions of metabolic stress. By receptor autoradiography, we have demonstrated that brain regions most vulnerable to injury during prolonged hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::172ca164d7563cef29d33d7616866b11
https://pubmed.ncbi.nlm.nih.gov/8127107
https://pubmed.ncbi.nlm.nih.gov/8127107
Autor:
J M, Redmond, A M, Gillinov, M E, Blue, K J, Zehr, J C, Troncoso, D E, Cameron, M V, Johnston, W A, Baumgartner
Publikováno v:
Surgery. 114(2)
Neurologic injury associated with prolonged hypothermic circulatory arrest (HCA) may be mediated by calcium-dependent glutamate excitotoxicity (GE). The monosialoganglioside GM1 has been shown in vitro to limit GE in conditions of metabolic stress. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2c913720110d756ca03c549ed0dec071
https://pubmed.ncbi.nlm.nih.gov/8393596
https://pubmed.ncbi.nlm.nih.gov/8393596