Zobrazeno 1 - 10
of 66
pro vyhledávání: '"J. C. Street"'
Publikováno v:
Biochemical Journal. 291:485-492
1. Heteronuclear 1H/15N n.m.r. experiments are described in which 15N labelling of cellular metabolites is detected via their proton resonances. 2. These n.m.r. experiments have been used to monitor label redistribution amongst extracellular metaboli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::297344b83c2e59b66f1f24ecdce76cb2
https://doi.org/10.1042/bj2910485
https://doi.org/10.1042/bj2910485
Publikováno v:
Cancer research. 57(18)
6-Aminonicotinamide (6AN) can be metabolized to 6-amino-NAD(P+), a competitive inhibitor of NAD(P+)-requiring processes, especially the pentose phosphate pathway (PPP) enzyme, 6-phosphogluconate dehydrogenase. The effect of 6AN on the flux of 1 and 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::40318e06c0dfa155f4b2a1ac3d82becb
https://pubmed.ncbi.nlm.nih.gov/9307279
https://pubmed.ncbi.nlm.nih.gov/9307279
Publikováno v:
NMR in biomedicine. 9(3)
The chemotherapeutic regimen of N-(phosphonacetyl)-L-aspartate (PALA) followed 17 h later by 6-methylmercaptopurine riboside (MMPR) and 6-aminonicotanamide (6AN) has been shown to be a potent sensitizer of anti-neoplastic therapy. We undertook this s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::177fba8ec7ea1670c1e60b1f0a20ba49
https://pubmed.ncbi.nlm.nih.gov/8892397
https://pubmed.ncbi.nlm.nih.gov/8892397
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 26(4)
1. Human cytochrome P450 2A6 is expressed in Chinese hamster lung fibroblasts. The isozyme hydroxylates coumarin at the 7-position. 2. Metabolism of coumarin in these lung fibroblasts was monitored using 1H-nmr. Media samples were taken from cells gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::513ccaf4d0fe0c016312d5483ac76521
https://pubmed.ncbi.nlm.nih.gov/9173685
https://pubmed.ncbi.nlm.nih.gov/9173685
Publikováno v:
Journal of Clinical Oncology. 28:9057-9057
9057 Background: While improvements in the complete control of emesis with NK1s in pts receiving cisplatin (DDP) have been well demonstrated, efficacy reports of this antiemetic class in pts given carboplatin (carbo) or oxaliplatin (oxali) have only
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::126910f759613e4f18ec9a7c5a889b59
https://doi.org/10.1200/jco.2010.28.15_suppl.9057
https://doi.org/10.1200/jco.2010.28.15_suppl.9057
Publikováno v:
Environmental Health Perspectives
Distribution of cadmium (Cd) into the edible products of three species of food-producing animals was investigated during long-term dietary administration of supplemental cadmium chloride. Cows were exposed to 0.2 (control), 2.4, and 11.3 ppm Cd on wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45a8c29a89cef538cd5bb2050a06ce10
https://doi.org/10.1289/ehp.792859
https://doi.org/10.1289/ehp.792859
Autor:
J. C. Street, R. P. Sharma
Publikováno v:
Comprehensive Physiology
The sections in this article are: 1 General Pharmacodynamics of Environmental Chemicals 2 Rates of Accumulation and Release for Different Chemicals 2.1 Short-Lived Chemicals 2.2 Long-Lived Chemicals 3 Physiological Factors in Accumulation and Release
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb70f4ebc4db88078e81402bdfcf6bfe
https://doi.org/10.1002/cphy.cp090130
https://doi.org/10.1002/cphy.cp090130
Publikováno v:
Journal of Food Safety. 2:247-255
Bush beans, carrots and tomatoes were shown to absorb 1,3-dichloro-propene from vermiculite, solution culture and sand. The dichloropro-pene was translocated and metabolized rapidly in the plant to 3-chloroallyl alcohol. The 3-chloroallyl alcohol its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c6e09b0a8be0f2a249897bfb22c6bec
https://doi.org/10.1111/j.1745-4565.1980.tb00401.x
https://doi.org/10.1111/j.1745-4565.1980.tb00401.x
Publikováno v:
Physical Review. 118:579-588
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61efa1982210bdd74b444d7bc3a80f4c
https://doi.org/10.1103/physrev.118.579
https://doi.org/10.1103/physrev.118.579
Publikováno v:
Bulletin of Environmental Contamination and Toxicology. 1:6-15
Selected drugs were tested for effectiveness in reducing dieldrin retention by rats. Female rats were fed diets treated to contain 1 ppm dieldrin. The drugs were administered as feed additives or by i.p. injections. The rats were sacrificed after 10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::945d228052db9a91adbee98d943e4fd8
https://doi.org/10.1007/bf01684070
https://doi.org/10.1007/bf01684070