Výsledky vyhledávání - "J. C. Renauld"

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Signals from the IL-9 Receptor Are Critical for the Early Stages of Human Intrathymic T Cell Development

Autor: Evelien Naessens, Georges Leclercq, Tessa Kerre, Dominique Vanhecke, Bruno Verhasselt, J Van Snick, Jean Plum, J.-C. Renauld, M De Smedt

Publikováno v: Ghent University Academic Bibliography
Scopus-Elsevier

Highly purified human CD34+ hemopoietic precursor cells differentiate into mature T cells when seeded in vitro in isolated fetal thymic lobes of SCID mice followed by fetal thymus organ culture (FTOC). Here, this chimeric human-mouse FTOC was used to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::722ab74e0318b091b0384cb27ee92a5a
https://doi.org/10.4049/jimmunol.164.4.1761

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Interleukin-9 Enhances Resistance to the Intestinal Nematode Trichuris muris

Autor: Richard K. Grencis, Helen Faulkner, J.-C. Renauld, J Van Snick

Publikováno v: Infection and Immunity. 66:3832-3840

Upon infection with the cecum-dwelling nematode Trichuris muris , the majority of inbred strains of mice launch a Th2-type immune response and in doing so expel the parasite before patency. In contrast, there are a few mouse strains which develop a n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b77d24697c21320f38f744372760d78
https://doi.org/10.1128/iai.66.8.3832-3840.1998

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Intraepithelial Infiltration by Mast Cells with Both Connective Tissue-Type and Mucosal-Type Characteristics in Gut, Trachea, and Kidneys of IL-9 Transgenic Mice

Autor: C, Godfraind, J, Louahed, H, Faulkner, A, Vink, G, Warnier, R, Grencis, J C, Renauld

Publikováno v: The Journal of Immunology. 160:3989-3996

IL-9 transgenic mice were analyzed for the presence of mast cells in different tissues. In these mice, increased mast cell infiltration was found in the gastric and intestinal epithelium as well as in the upper airways and kidney epithelium, but not

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fdc6f50ed51ee2fb392b07aa34057ad
https://doi.org/10.4049/jimmunol.160.8.3989

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Costimulation with B7-1, IL-6, and IL-12 is sufficient for primary generation of murine antitumor cytolytic T lymphocytes in vitro

Autor: T F Gajewski, J C Renauld, A Van Pel, T Boon

Publikováno v: The Journal of Immunology. 154:5637-5648

The requirements for generating CD8+ CTLs against the mastocytoma P815 were first defined by using an allogeneic mixed lymphocyte tumor culture (MLTC). Both the expansion of effector lymphocytes and the acquisition of lytic activity were dependent on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9d4f76bd0f35dcb384efd0329cb614f8
https://doi.org/10.4049/jimmunol.154.11.5637

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Cloning and chromosomal localization of a pseudogene corresponding to a mRNA for a soluble IL-6 receptor

Autor: L. Snyers, J. C. Renauld, C. Szpirer, J. Content

Publikováno v: DNA Sequence. 5:311-314

A polymerase chain reaction assay (Lust J.A. et al. (1992). Cytokine 4:96-100) was used to detect a mRNA coding for a soluble IL-6 receptor in human hepatoma cells. In addition to the expected amplification product, we found a sequence (SR4) which co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d25582aebfe747161caa234e6e725985
https://doi.org/10.3109/10425179509030986

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[Role of interleukin-9 in asthma and allergic reactions]

Autor: J-C, Renauld

Publikováno v: Bulletin et memoires de l'Academie royale de medecine de Belgique. 162(5-6)

Interleukin 9 (IL-9) is a cytokine produced by activated T lymphocytes and that activates in vitro mast cells as well as T and B lymphocytes. In vivo, transgenic mice overexpressing the gene encoding IL-9 show several of the hallmarks of human allerg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8f541950f9e42fccf49980d670c03b61
https://pubmed.ncbi.nlm.nih.gov/18404997

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Human P40/IL-9. Expression in activated CD4+ T cells, genomic organization, and comparison with the mouse gene

Autor: J C Renauld, A Goethals, F Houssiau, H Merz, E Van Roost, J Van Snick

Publikováno v: The Journal of Immunology. 144:4235-4241

P40 is a cytokine that was originally identified in the mouse as a T cell growth factor, but whose spectrum of potential targets was recently shown to include mast cells as well as megakaryoblastic leukemic cells. Given these multiple activities, it

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a06db942d0187560677215f15c97539d
https://doi.org/10.4049/jimmunol.144.11.4235

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Interleukin-22 deficiency accelerates the rejection of full major histocompatibility complex-disparate heart allografts

Autor: Lionel F. Poulin, Michel Goldman, Michel Y Braun, Panayota Kapessidou, J.-C. Renauld, Laure Dumoutier

Publikováno v: Transplantation proceedings. 40(5)

Interleukin-22 (IL-22) was recently described as an effector cytokine produced by TH17 CD4(+) T lymphocytes that, cooperatively with IL-17, mediates IL-23-driven inflammation. Because there was experimental evidence for the role of IL-17 in acute rej

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f98baeaec78e17bddb9b41b158a7798e
https://pubmed.ncbi.nlm.nih.gov/18589157

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