Zobrazeno 1 - 10
of 15
pro vyhledávání: '"J. C. M. Stewart"'
Autor:
Hans-Beat Ris, H. J. Altermatt, J. C. M. Stewart, A. McGuinness, M. L. De Jode, M. F. Grahn, A. Giger, Norman S. Williams
Publikováno v:
Lasers in Medical Science. 14:40-46
The in vivo photodynamic activities of four poly(ethylene glycol) (PEG) conjugates of the photosensitiser 5,10,15,20-tetrakis-(m-hydroxyphenyl)chlorin (mTHPC, temoporfin, Foscan(®)) were compared with that of mTHPC over a range of drug-light interva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b472f0b0bccd0f3d1514d21dee36ac1
https://doi.org/10.1007/s101030050019
https://doi.org/10.1007/s101030050019
Autor:
A. Giger, Thorsten Krueger, J. C. M. Stewart, Chang Kee Lim, Hans-Beat Ris, H. J. Altermatt, Ulrich Althaus
Publikováno v:
British Journal of Cancer
British Journal of Cancer, vol. 79, no. 7-8, pp. 1061-1066
British Journal of Cancer, vol. 79, no. 7-8, pp. 1061-1066
The photosensitizing properties of m-tetrahydroxyphenylchlorin (mTHPC) and polyethylene glycol-derivatized mTHPC (pegylated mTHPC) were compared in nude mice bearing human malignant mesothelioma, squamous cell carcinoma and adenocarcinoma xenografts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::110df4937278e464dffba5039b4101b9
https://doi.org/10.1038/sj.bjc.6690170
https://doi.org/10.1038/sj.bjc.6690170
Autor:
K. Gharehbaghi, W. Grünberger, Barbara Krammer, J. C. M. Stewart, F. Wierrani, Dagmar Fiedler, Gerlinde Schnitzhofer
Publikováno v:
Journal of Photochemistry and Photobiology B: Biology. 38:241-244
The efficiency of a new photosensitizer of the second generation, meso-tetra-hydroxyphenyl-chlorin (mTHPC), which has a strong absorption at 652 nm, was investigated by oxygen consumption measurements and membrane integrity testing. The experiments p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::616d0b0d2a451b168981ed9da6d14011
https://doi.org/10.1016/s1011-1344(96)07463-5
https://doi.org/10.1016/s1011-1344(96)07463-5
Autor:
Helmut Messmann, C. E. Millson, J. C. M. Stewart, Sg Bown, A. J. MacRobert, M. Pauer, P Mlkvy
Publikováno v:
British Journal of Cancer
Photodynamic therapy (PDT) has the potential to destroy small tumours with safe healing of adjacent normal tissue. This study looks at the effects of PDT on the normal pancreas and adjacent tissues in hamsters using the photosensitiser meso-tetrahydr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2600aeaedadae98e8e5b3d1bb0f8b62
https://doi.org/10.1038/bjc.1996.279
https://doi.org/10.1038/bjc.1996.279
Autor:
R. Bonnett, Hans-Beat Ris, B. Nachbur, J. C. M. Stewart, Chang Kee Lim, Ulrich Althaus, Qiang Wang, H. J. Altermatt
Publikováno v:
International Journal of Cancer. 53:141-146
The influence of the time interval (TI) between drug administration and laser activation on selectivity of meta-tetrahydroxy- phenylchlorin(mTHPC)-mediated photodynamic therapy (PDT) for tumour tissue was assessed in BALB/c nude mice bearing human ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5013ba8abc3fac2fba364ebe9d8daa2
https://doi.org/10.1002/ijc.2910530126
https://doi.org/10.1002/ijc.2910530126
Autor:
Raymond Bonnett, Q. Wang, Hans-Beat Ris, H. J. Altermatt, B. Nachbur, R. Hess, R. Inderbitzi, M. C. Berenbaum, J. C. M. Stewart, Chang Kee Lim
Publikováno v:
British Journal of Cancer
Four patients underwent intraoperative photodynamic therapy after surgery with meso-tetra-(hydroxyphenyl)-chlorin (mTHPC-PDT) for diffuse malignant mesothelioma. Preliminary procedures were performed in two patients in order to establish the efficacy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7fa27a4fedd39826b4dd9072a277d07
https://doi.org/10.1038/bjc.1991.474
https://doi.org/10.1038/bjc.1991.474
Autor:
Daniel Mettler, A. Giger, H. J. Altermatt, Hans-Beat Ris, Vinzenz Im Hof, Ulrich Althaus, J. C. M. Stewart
Publikováno v:
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery. 12(4)
Objective: Photodynamic therapy (PDT) with two chlorin sensitisers was assessed on nude mice bearing human mesothelioma xenografts, and on intrathoracic tissues of minipigs with the same drug-light conditions to optimise the antitumour activity of PD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1686c887552d1827e8053ba5da49bb0b
https://pubmed.ncbi.nlm.nih.gov/9370396
https://pubmed.ncbi.nlm.nih.gov/9370396
Autor:
Stephen G. Bown, J. C. M. Stewart, Peter Mlkvy, Alexander J. MacRobert, Helmut Messmann, C. E. Millson, M. Pauer
Publikováno v:
SPIE Proceedings.
Experimental study has been carried out using metatetrahydroxyphenylchlorin (m-THPC) in female Syrian golden hamsters. For quantitative fluorescence study, using a CCD camera, the dose of 1.0 mg/kg bodyweight of mTHPC was given intracaval and animals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2bfc596c812525cf1bfe43c8096ea357
https://doi.org/10.1117/12.203355
https://doi.org/10.1117/12.203355
Autor:
Raymond Bonnett, H. J. Altermatt, J. C. M. Stewart, Brenda Reynolds, Hans-Beat Ris, Chang Kee Lim, Qiang Wang
Publikováno v:
Biomedical chromatography : BMC. 7(1)
A high performance liquid chromatographic method for the determination of the photodynamic chemotherapeutic agent 5,10,15,20-tetra(m-hydroxyphenyl)chlorin (m-THPC) in human plasma following intravenous infusion is described. The procedure involves ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7765e5c365ba20fdaad64c8f5b41b3b8
https://pubmed.ncbi.nlm.nih.gov/8431680
https://pubmed.ncbi.nlm.nih.gov/8431680
Publikováno v:
The Lancet. 339:1232-1233
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7552ea28245676746d165441cd16c527
https://doi.org/10.1016/0140-6736(92)91173-6
https://doi.org/10.1016/0140-6736(92)91173-6