Zobrazeno 1 - 10
of 34
pro vyhledávání: '"J. C. Lacal"'
Autor:
M P Moyer, J C Lacal Sanjuan, Elsa Sanchez-Lopez, T Zimmerman, Arancha Cebrián, T Gomez del Pulgar
Publikováno v:
Cell death & disease, vol 4, iss 11
Digital.CSIC. Repositorio Institucional del CSIC
instname
Cell Death & Disease
Digital.CSIC. Repositorio Institucional del CSIC
instname
Cell Death & Disease
11 p.-6 fig.
Endoplasmic reticulum (ER) is a central organelle in eukaryotic cells that regulates protein synthesis and maturation.Perturbation of ER functions leads to ER stress, which has been previously associated with a broad variety of dise
Endoplasmic reticulum (ER) is a central organelle in eukaryotic cells that regulates protein synthesis and maturation.Perturbation of ER functions leads to ER stress, which has been previously associated with a broad variety of dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91cea0dbc07605c317b9b6b6f515413d
https://escholarship.org/uc/item/4gp5f8bk
https://escholarship.org/uc/item/4gp5f8bk
Publikováno v:
Journal of Biological Chemistry. 265:19405-19408
rap1B is a member of the ras superfamily of low molecular weight GTP binding proteins which constitutes a focal point of GTP and cAMP signal transduction systems. Like other members of this superfamily, rap1B is membrane-associated in resting platele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feac6b89566b07f7da98fbb33ddc45c2
https://doi.org/10.1016/s0021-9258(17)45385-3
https://doi.org/10.1016/s0021-9258(17)45385-3
Autor:
J C, Lacal
Publikováno v:
IDrugs : the investigational drugs journal. 4(4)
Malignant cells are characterized by the accumulation of genetic alterations, which result in the disregulation of signal transduction pathways that control proliferation, differentiation and apoptosis. The identification of the molecular components
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1dd9047ac7003ecf8723728b0965f863
https://pubmed.ncbi.nlm.nih.gov/16015482
https://pubmed.ncbi.nlm.nih.gov/16015482
Publikováno v:
Progress in molecular and subcellular biology. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::648e04787e9ed4504e67a516172e9246
https://pubmed.ncbi.nlm.nih.gov/15171618
https://pubmed.ncbi.nlm.nih.gov/15171618
Publikováno v:
Viruses and Apoptosis ISBN: 9783540742630
The knowledge of the cellular events that take place during the development of a disease is crucial for establishing effective therapies. During the last three decades, the design of antitumoral agents has been primarily based on the fact that tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8408711234ac07e5d70dd67fd6b8f94d
https://doi.org/10.1007/978-3-540-74264-7_15
https://doi.org/10.1007/978-3-540-74264-7_15
Autor:
S, Aznar, J C, Lacal
Publikováno v:
Progress in nucleic acid research and molecular biology. 67
The Ras superfamily of low-molecular-weight GTPases are proteins that, in response to diverse stimuli, control key cellular processes such as cell growth and development, apoptosis, lipid metabolism, cytoarchitecture, membrane trafficking, and transc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::204d6ff6f7ed4eea450d6042a3b95635
https://pubmed.ncbi.nlm.nih.gov/11525383
https://pubmed.ncbi.nlm.nih.gov/11525383
Publikováno v:
Cancer research. 59(13)
Transformation by some oncogenes is associated with increased activity of choline kinase (ChoK), resulting in elevated constitutive levels of phosphorylcholine, a proposed second messenger required for DNA synthesis induced by growth factors. Here we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::12e862dd2f043ab0e5987adffd89125d
https://pubmed.ncbi.nlm.nih.gov/10397253
https://pubmed.ncbi.nlm.nih.gov/10397253
Publikováno v:
Microinjection ISBN: 9783764360191
Microinjection of macromolecules into living cells has proved to be a powerful technique for the functional analysis of gene products in living somatic cells. This approach is useful for the introduction of functional proteins, genes, inhibitors of e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21d21dcc6bbcb69b94bd5af149a1209f
https://doi.org/10.1007/978-3-0348-8705-2_2
https://doi.org/10.1007/978-3-0348-8705-2_2
Autor:
J. C. Lacal, A. Carnero
Publikováno v:
Microinjection ISBN: 9783764360191
The mammalian ras genes (H-ras, K-ras and N-ras) encode a family of closely related 21 kDa proteins that are members of the superfamily of GTP binding proteins (G-proteins). Ras proteins participate in a number of intracellular signalling pathways, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4db47dd1c27edd3631ba20b73faec640
https://doi.org/10.1007/978-3-0348-8705-2_13
https://doi.org/10.1007/978-3-0348-8705-2_13
Autor:
J. C. Lacal, A. Carnero
Publikováno v:
Microinjection ISBN: 9783764360191
As indicated in the previous chapter, Xenopus laevis oocytes are arrested at the G2/M border of the first meiotic prophase. After progesterone treatment, a complex process of intracellular signals is activated which ends in the maturation of the oocy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc3fd354fb59473faef29cb8e66a26b4
https://doi.org/10.1007/978-3-0348-8705-2_12
https://doi.org/10.1007/978-3-0348-8705-2_12