Zobrazeno 1 - 10
of 44
pro vyhledávání: '"J. C. Kingswood"'
Autor:
M. Smeaton, Patrick Bolton, Ingram Wright, Julian R. Sampson, J. C. Kingswood, Alasdair Parker, Sam Amin, Daniel P. Gale, Frances Elmslie, Finbar O'Callaghan, C. Harland, Simon R. Johnson
Publikováno v:
QJM: An International Journal of Medicine. 112:171-182
Background\ud The severity of Tuberous Sclerosis Complex (TSC) can vary among affected individuals. Complications of TSC can be life threatening, with significant impact on patients’ quality of life. Management may vary dependent on treating physic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5157561246fb251bef2d8c6ed5c103f8
https://doi.org/10.1093/qjmed/hcy215
https://doi.org/10.1093/qjmed/hcy215
Autor:
Michael Frost, Shweta R. Urva, David Chen, John J. Bissler, Klemens Budde, Bernard A. Zonnenberg, Karen Stein, Wing Cheung, Thomas Brechenmacher, J. C. Kingswood
Publikováno v:
British Journal of Clinical Pharmacology. 81:958-970
Aims The purpose was to determine the exposure-response relationship of everolimus in patients with angiomyolipoma from the EXIST-2 trial and to analyze the correlation between exposure and plasma concentrations of angiogenic biomarkers in these pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::680292dae007703ac29ba44aa778ebf7
https://doi.org/10.1111/bcp.12834
https://doi.org/10.1111/bcp.12834
Publikováno v:
Orphanet Journal of Rare Diseases
Tuberous sclerosis complex (TSC) is a genetic disorder characterised by highly variable comorbid dysfunction and subsequent morbidity. The mTOR inhibitor everolimus is indicated for the treatment of adult TSC patients with renal angiomyolipomas (AMLs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e76b2571588417b1ed8864efa26a7d66
https://orca.cardiff.ac.uk/id/eprint/102634/1/0530.pdf
https://orca.cardiff.ac.uk/id/eprint/102634/1/0530.pdf
Autor:
Pamela Crawford, Matthew Magestro, Simon R. Johnson, Melissa Myland, Alun Pinnegar, Charles Shepherd, Dirk Demuth, Keyur Patel, Julian R. Sampson, Clement Erhard, Elizabeth Gray, P Nasuti, J. C. Kingswood
Publikováno v:
Journal of medical economics. 19(11)
Tuberous sclerosis complex (TSC) is a multi-system genetic disorder characterized by the development of diverse clinical manifestations. The complexity of this disease is likely to result in substantial challenges and costs in disease management thro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eaa80363cd51c16954aeeb25733b77e
https://pubmed.ncbi.nlm.nih.gov/27267148
https://pubmed.ncbi.nlm.nih.gov/27267148
Autor:
John J. Bissler, J. C. Kingswood
Publikováno v:
Therapeutic Advances in Urology, Vol 8 (2016)
Renal angiomyolipomata associated with tuberous sclerosis complex are often bilateral, multiple and progressive. They cause significant morbidity and mortality in older children and adults. Surveillance and pre-emptive treatment reduce this risk. Rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c65884c7ba95b497f42888621b7554fa
https://doaj.org/article/65b3d559fac342a59a70edd5d112455b
https://doaj.org/article/65b3d559fac342a59a70edd5d112455b
Publikováno v:
Journal of medical economics. 19(12)
Tuberous sclerosis complex (TSC) is a multi-system genetic disorder in which renal manifestations occur in ∼50% of children and 80% of adults. Since these often present alongside other manifestations, renal TSC is likely to incur significant costs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2bf0594740f97be43700157aa4caa36
https://pubmed.ncbi.nlm.nih.gov/27310569
https://pubmed.ncbi.nlm.nih.gov/27310569
Autor:
John J. Bissler, J. C. Kingswood, Norio Nonomura, Bernard A. Zonnenberg, Severine Peyrard, Petrus J. de Vries, Michael Frost, Elżbieta Radzikowska, Noah Berkowitz, Elena Belousova, Susanne Brakemeier, Klemens Budde, Matthias Sauter
Publikováno v:
Journal of Urology. 193
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8cd66111c5ebe201917647a21db91d3c
https://doi.org/10.1016/j.juro.2015.02.2233
https://doi.org/10.1016/j.juro.2015.02.2233
Autor:
Susanne Brakemeier, Klemens Budde, Bernard A. Zonnenberg, Michael Frost, Scott Segal, Matthias Sauter, John J. Bissler, J. C. Kingswood, Elena Belousova, Petrus J. de Vries, Severine Peyrard, Elżbieta Radzikowska, Noah Berkowitz, Norio Nonomura, Sara Miao
Publikováno v:
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 31(1)
Mammalian target of rapamycin (mTOR) inhibitors are recommended as first-line treatment of renal angiomyolipoma associated with tuberous sclerosis complex (TSC) or sporadic lymphangioleiomyomatosis (sporadic LAM), but follow-up is limited. Longer ter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfc006bafe95dfb09ba5a8b72a6716c0
https://pubmed.ncbi.nlm.nih.gov/26156073
https://pubmed.ncbi.nlm.nih.gov/26156073
Autor:
Sergiusz Jozwiak, Christoph Hertzberg, Stefania Crippa, José C Ferreira, Paolo Curatolo, Rima Nabbout, Sotirios Youroukos, Maria Dahlin, Petrus J. de Vries, Mirjana P Benedik, Silvia Comis, J. C. Kingswood, Tom Carter, Renaud Touraine, Finbar O'Callaghan, Ramon Castellana, Paolo Bruzzi, Bernard A. Zonnenberg, Valentin Sander, Alfons Macaya, Anna Jansen, Martha Feucht, Vincent Cottin, Matthias Sauter, Elena Belousova, Bulent Ulker, Carla Fladrowski, Guillaume Beaure d'Augères
Publikováno v:
Orphanet Journal of Rare Diseases
Background Tuberous sclerosis complex (TSC) is a rare, multisystem, genetic disorder with an estimated prevalence between 1/6800 and 1/15000. Although recent years have seen huge progress in understanding the pathophysiology and in the management of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0669b3fa2f11798d3253b6ce6e67b994
https://hdl.handle.net/11427/13610
https://hdl.handle.net/11427/13610