Zobrazeno 1 - 10
of 49
pro vyhledávání: '"J. C. Izpisúa-Belmonte"'
Publikováno v:
Nature. 350:585-589
The chicken Hox-4 homeogenes, like those of the mouse, are coordinately expressed in partially overlapping domains during wing development. Local application of retinoic acid, a putative endogenous morphogen, induces de novo transcription of Hox-4 ge
Autor:
L. da F. Costa, B. A. N. Travençolo, A. Azeredo, M. E. Beletti, G. B. Müller, D. Rasskin-Gutman, G. Sternik, M. Ibañes, J. C. Izpisúa-Belmonte
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
We present a vector field method for obtaining the spatial organization of 3D patterns of gene expression based on gradients and lines of force obtained by numerical integration. The convergence of these lines of force in local maxima are identified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ee65955d2dd4c01e00d6f0e9a6b26b3
Autor:
J, Capdevila, J C, Izpisúa Belmonte
Publikováno v:
The Journal of experimental zoology. 288(4)
The study of the origin and evolution of the tetrapod limb has benefited enormously from the confluence of molecular and paleontological data. In the last two decades, our knowledge of the basic molecular mechanisms that control limb development has
Autor:
B, Blumberg, J C, Izpisúa Belmonte
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 97
Publikováno v:
The Journal of experimental zoology. 284(2)
Sonic hedgehog (shh) expression is detectable in the posterior mesenchyme of many developing vertebrate limbs. We have isolated an RT-PCR fragment from the axolotl, Ambystoma mexicanum, that has high identity to other vertebrate shh genes. We describ
Publikováno v:
Current topics in developmental biology. 41
The body plan is generated by cells and tissues that become arranged precisely in the embryo. This process, termed pattern formation, involves cell interactions in which a particular group of cells produce signals that specify new cell types or patte
Publikováno v:
Developmental genetics. 19(1)
Several polydactylous mutants affect the pattern of asymmetry along the anteroposterior axis of the vertebrate limb. In talpid2, diplopodia1, and diplopodia4 chick limb mutants, there is a preaxial extension that results in broader limb buds. Talpid2
Publikováno v:
Nature. 378(6558)
The positional cues that govern the fate of cells along the dorsoventral axis of the developing vertebrate limb are established in the mesoderm before outgrowth of limb buds. In Drosophila, a LIM/-homeodomain gene, apterous, expressed in the dorsal c
Autor:
Cheryll Tickle, C. Rodriguez, D.A. Ede, Paul M. Brickell, Philippa H. Francis-West, K. E. Robertson, David W. Burt, J. C. Izpisúa-Belmonte, C. Gribbin, B. Houston
Publikováno v:
ResearcherID
The chicken mutant talpid3 (ta3) has polydactylous limbs with up to 7-8 morphologically similar digits. This lack of antero-posterior polarity in digit pattern is correlated with symmetrical expression of genes of the HoxD complex. We determined the