Zobrazeno 1 - 10
of 352
pro vyhledávání: '"J. C. Harris"'
Autor:
J. C. Harris, S. T. Grilli
Publikováno v:
Nonlinear Processes in Geophysics, Vol 21, Iss 6, Pp 1169-1184 (2014)
Wave-induced boundary layer (BL) flows over sandy rippled bottoms are studied using a numerical model that applies a one-way coupling of a "far-field" inviscid flow model to a "near-field" large eddy simulation (LES) Navier–Stokes (NS) model. Th
Externí odkaz:
https://doaj.org/article/8670ecc6dd8f496b9c49d78e3ba6ae87
Autor:
Junior J West, Tony J C Harris
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0239357 (2020)
Cytohesin Arf-GEFs promote actin polymerization and protrusions of cultured cells, whereas the Drosophila cytohesin, Steppke, antagonizes actomyosin networks in several developmental contexts. To reconcile these findings, we analyzed epidermal leadin
Externí odkaz:
https://doaj.org/article/7c9f3fb76a934aceb07d077c8e0a8f34
Autor:
Tony J. C. Harris
Publikováno v:
F1000Research, Vol 6 (2017)
The scaffold protein Par-3 (Drosophila Bazooka) is a central organizer of cell polarity across animals. This review focuses on how the clustering of Par-3 contributes to cell polarity. It begins with the Par-3 homo-oligomerization mechanism and its r
Externí odkaz:
https://doaj.org/article/9207b6e446a74a42a66badc7b70969ec
Publikováno v:
Molecular Biology of the Cell. 33
During Drosophila dorsal closure, the SCAR/WAVE complex localizes to adherens junctions of the leading edge actomyosin cable in response to myosin activators and the junctional Arf-GEF Steppke.
Publikováno v:
British Dental Journal. 228:93-97
Introduction: Preformed metal crowns (PMC) placed using the Hall Technique (HT) are effective for managing carious lesions in primary molars and might be tolerable and successful for children with learning disabilities (CLD), possibly avoiding the ne
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142562 (2015)
The recruitment of GDP/GTP exchange factors (GEFs) to specific subcellular sites dictates where they activate small G proteins for the regulation of various cellular processes. Cytohesins are a conserved family of plasma membrane GEFs for Arf small G
Externí odkaz:
https://doaj.org/article/0093012d9c134956bd429f9803d77a94
Autor:
Tony J. C. Harris, Tao Jiang
Publikováno v:
The Journal of Cell Biology
The cell cortex is populated by various proteins, but it is unclear how they interact to change cell shape. Jiang and Harris find that the kinase Par-1 is required for Diaphanous-based actin bundles, and that these bundles intersperse with separately
Autor:
Milena Pellikka, Norbert Perrimon, Frederik Wirtz-Peitz, Ulrich Tepass, Takashi Nishimura, Dong Yan, Jordan T. Silver, Yan Li, Tony J. C. Harris, Sérgio Simões, Richard Binari
Publikováno v:
The Journal of Cell Biology
Silver et al. show that the RhoGEF Cysts links apical polarity proteins to Rho1 and myosin activation at adherens junctions to support junctional and epithelial integrity in the Drosophila ectoderm.
The spatio-temporal regulation of small Rho GT
The spatio-temporal regulation of small Rho GT
Publikováno v:
Molecular Biology of the Cell
Tissue dynamics require regulated interactions between adherens junctions and cytoskeletal networks. For example, myosin-rich adherens junctions recruit the cytohesin Arf-GEF Steppke, which down-regulates junctional tension and facilitates tissue str