Zobrazeno 1 - 10
of 17
pro vyhledávání: '"J. C. Fitzpatrick"'
Publikováno v:
Acta Horticulturae. :193-202
Publikováno v:
Journal of Surgical Research. 49:293-297
Carcinine (beta-alanylhistamine) is an imidazole dipeptide that exists in mammalian hearts, increases cardiac contractility, and is metabolically linked to carnosine (beta-alanylhistidine), a non-mast cell histidine and histamine precursor during str
Autor:
J. C. Fitzpatrick, David N. Brotman, Theodorus van Es, E. Kasziba, Hans Fisher, Louis Flancbaum
Publikováno v:
Life Sciences. 47:1587-1593
Carcinine (β-alanylhistamine) was synthesized in vitro from histamine and β-alanine. It was detected quantitatively using an HPLC method previously described for the quantification of the related compounds histamine, histidine, carnosine and 3-meth
Publikováno v:
Agents and actions. 31(3-4)
Histamine is known to exert profound effects on the cardiovascular system in many mammals. Carnosine (beta-alanyl-L-histidine) is a dipeptide previously known to be present only in a few tissues. It is our hypothesis that carnosine serves as a non-ma
Publikováno v:
The Journal of surgical research. 49(4)
Carcinine (beta-alanylhistamine) is an imidazole dipeptide that exists in mammalian hearts, increases cardiac contractility, and is metabolically linked to carnosine (beta-alanylhistidine), a non-mast cell histidine and histamine precursor during str
Publikováno v:
Circulatory shock. 32(2)
The roles of histamine and H1 and H2 receptors in shock are uncertain. We have found that treatment of aged rats with compound 48/80 (a mast cell degranulator) produced lethal (LD99) shock which was completely prevented by lodoxamide (LOD), a mast ce
Publikováno v:
Circulatory shock. 30(2)
Histamine exerts profound effects on the cardiovascular system during shock mediated by H1 and H2 receptors. The source of histamine is uncertain. It is our hypothesis that carnosine serves as a nonmast-cell reservoir for histidine, utilized for hist
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 432:315-320
Publikováno v:
Experimental Biology and Medicine. 191:90-92
Compound 48/80 has previously been shown to improve wound healing in rats, presumably through stimulation of histidine decarboxylase activity and mobilization of histamine from mast cells. In the present study, C57Bl/6 mice were wounded by dorsal ski
Publikováno v:
Circulatory shock. 27(2)
The precise roles of carnosine and histamine in the physiologic response of the cardiovascular system to stress are unknown. We have previously shown in skeletal and cardiac muscle that carnosine serves as a histidine reservoir available for subseque