Zobrazeno 1 - 10 of 17 pro vyhledávání: '"J. C. Clapham"'
1
Excess recovery heat production by isolated muscles from mice overexpressing uncoupling protein‐3
Autor: Nancy A. Curtin, Christopher John Barclay, J. C. Clapham
Publikováno v: The Journal of Physiology. 542:231-235
Contractile and energetic performance of bundles of muscle fibres from the soleus of mice overexpressing uncoupling protein 3 (UCP-3tg) were compared with the performance of bundles from wild-type mice. Force and heat production were measured during
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88622027700297a4e5fe6cda80f81c02
https://doi.org/10.1113/jphysiol.2002.021964
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3
Elevated Renal Endothelin-1 Clearance and mRNA Levels Associated with Albuminuria and Nephropathy in Non-Insulin-Dependent Diabetes Mellitus: Studies in Obese fa/fa Zucker Rats
Autor: J. C. Clapham, M. Vidgeon-Hart, A. C. Haynes, P. J. Morgan, N. Toseland, N. C. Turner
Publikováno v: Clinical Science. 93:565-571
1. The obese fa/fa Zucker rat is a genetic model of obesity and insulin resistance which develops a number of metabolic and endocrine features of non-insulin-dependent diabetes, including hypertension, proteinuria and glomerular sclerosis. 2. We have
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2168fa2864986bbb61e752865b6497a9
https://doi.org/10.1042/cs0930565
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5
Feeding behaviour in galanin knockout mice supports a role of galanin in fat intake and preference
Autor: A C, Adams, J C, Clapham, D, Wynick, J R, Speakman
Publikováno v: Journal of neuroendocrinology. 20(2)
It has been widely suggested that saturated fat consumption has fuelled the current obesity epidemic. Macronutrient choices appear to be important not only as potential factors influencing obesity, but also independently as risk factors for diabetes,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f34edcfdc2a761602ac08c9e4eb23dcf
https://pubmed.ncbi.nlm.nih.gov/18088361
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7
Increased fatty acid oxidation in transgenic mice overexpressing UCP3 in skeletal muscle
Autor: S, Wang, A, Subramaniam, M A, Cawthorne, J C, Clapham
Publikováno v: Diabetes, obesitymetabolism. 5(5)
To determine the rates of substrate oxidation by skeletal muscle in vitro as well as tissue-specific glucose uptake in vivo in transgenic mice overexpressing uncoupling protein-3 (UCP3) in skeletal muscle.Soleus muscle was isolated from transgenic mi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d22634b3d3ba32bb39ea131997293df2
https://pubmed.ncbi.nlm.nih.gov/12940866
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8
A longitudinal magnetic resonance imaging (MRI) study of differences in abdominal fat distribution between normal mice, and lean overexpressers of mitochondrial uncoupling protein-3 (UCP-3)
Autor: K K, Changani, A, Nicholson, A, White, J K, Latcham, D G, Reid, J C, Clapham
Publikováno v: Diabetes, obesitymetabolism. 5(2)
To characterize evolution and distribution of abdominal adipose fat between 6 and 18 weeks of age in an animal model of energy consumption based on mice overexpressing the mitochondrial uncoupler protein 3 (UCP-3).T2-weighted multislice MRI was perfo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c989bcee4deb5fc0ab18de9c8818b6ba
https://pubmed.ncbi.nlm.nih.gov/12630934
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9
Insulin resistance, impaired glucose tolerance and non-insulin-dependent diabetes, pathologic mechanisms and treatment: current status and therapeutic possibilities
Autor: N C, Turner, J C, Clapham
Publikováno v: Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques. 51
Impaired glucose tolerance and non-insulin-dependent diabetes (NIDDM) are the pathologic consequence of two co-incident and interacting conditions, namely insulin resistance and relative insulin deficiency. Recognised by the World Health Authority as
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::426b4dd4e736e0482bc6646718359ef6
https://pubmed.ncbi.nlm.nih.gov/9949859
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10
Elevated renal endothelin-I clearance and mRNA levels associated with albuminuria and nephropathy in non-insulin-dependent diabetes mellitus: studies in obese fa/fa Zucker rats
Autor: N C, Turner, P J, Morgan, A C, Haynes, M, Vidgeon-Hart, N, Toseland, J C, Clapham
Publikováno v: Clinical science (London, England : 1979). 93(6)
1. The obese fa/fa Zucker rat is a genetic model of obesity and insulin resistance which develops a number of metabolic and endocrine features of non-insulin-dependent diabetes, including hypertension, proteinuria and glomerular sclerosis. 2. We have
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1a6986cdc0623f7153ab748acf3fdf63
https://pubmed.ncbi.nlm.nih.gov/9497794
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