Zobrazeno 1 - 10
of 117
pro vyhledávání: '"J. C. Biggs"'
Publikováno v:
Arthritis & Rheumatism. 42:2286-2292
Objective. Based on animal studies and anecdotal case reports, high-dose therapy and autologous blood stem cell rescue have been proposed as an experimental treatment for severe, refractory rheumatoid arthritis (RA). This study aimed to establish the
Autor:
Sam Milliken, John A. Snowden, F. Passuello, J. Renwick, Peter Brooks, A. Fuller, J. C. Biggs, D. Staniforth
Publikováno v:
Bone Marrow Transplantation. 22:1035-1041
Autologous haemopoietic stem cell transplantation (HSCT) represents a potential therapy for severe rheumatoid arthritis (RA). As a prelude to clinical trails, the safety and efficacy of haemopoietic stem cell (HSC) mobilisation required investigation
Autor:
John A. Snowden, John Zaunders, V Nink, M Keir, Louise Wright, J. C. Biggs, Peter Brooks, Margaret A. Cooley, Sam Milliken
Publikováno v:
British Journal of Haematology. 103:601-609
High-dose chemotherapy with autologous stem cell rescue has been proposed as an intensive therapy for severe rheumatoid arthritis (RA). In view of previous observations of abnormal haemopoiesis in RA patients, the composition and function of peripher
Publikováno v:
Immunology and Cell Biology. 75:289-294
A granulocyte/macrophage colony-stimulating factor (GM-CSF)-Pseudomonas exotoxin (PE) 40 fusion protein was constructed for potential use in the treatment of myeloid leukaemias, as a conditioning agent prior to allogeneic bone marrow transplantation
Publikováno v:
Journal of Clinical Immunology. 17:502-509
Proteins with glycosylphosphatidylinositol (GPI) anchors exhibit a range of activities and some of these proteins exist in both a membrane-associated and a soluble form. CD48 is a 47-kd GPI-linked glycoprotein which is expressed on T and B lymphocyte
Autor:
A. J. Henniker, Kenneth F. Bradstock, J. C. Biggs, Kerry Atkinson, Glenn M. Smith, Robyn L. Ward
Publikováno v:
Immunology and Cell Biology. 72:49-55
WM65 is a murine mAb which recognizes a novel surface membrane antigen present on leukaemic and normal leucocytes. The present study further investigates the nature of this antigen, especially those features which relate to the possible therapeutic a
Publikováno v:
Australian and New Zealand Journal of Medicine. 23:151-156
A retrospective analysis of 125 consecutive lupus anticoagulant (LA) positive patients and 125 age, sex matched lupus anticoagulant negative controls is reported with the aims of defining further the clinical spectrum of disease, determining at-risk
Autor:
Kerry Atkinson, P. Tutschka, K. Downs, Alan J. Concannon, Isadore Brodsky, Jeff Szer, N. Kapoor, J. C. Biggs, P. Crilley, Edward A. Copelan, David Topolsky, B. Avalos, Anthony J. Dodds, S Bulova
Publikováno v:
Scopus-Elsevier
One hundred fifteen patients with chronic myelocytic leukemia (CML) were administered busulphan 4 mg/kg for 4 days and cyclophosphamide 60 mg/kg on each of 2 days (BuCy2) followed by allogeneic bone marrow transplantation from histocompatible sibling
Autor:
K. Downs, J. L. Klein, Isabel Cunningham, Jeff Szer, Kapoor N, Edward A. Copelan, Kerry Atkinson, John P. Klein, J. C. Biggs, Belinda R. Avalos
Publikováno v:
Journal of Clinical Oncology. 10:237-242
PURPOSE The study was undertaken to investigate the effectiveness of allogeneic bone marrow transplantation from HLA-identical siblings after preparation with busulfan and cyclophosphamide in adults with acute lymphoblastic leukemia (ALL). PATIENTS A
Autor:
John P. Klein, J. C. Biggs, Kapoor N, Edward A. Copelan, Jeff Szer, Belinda R. Avalos, J. M. Thompson, Isabel Cunningham, Pamela Crilley, K Atkinson
Publikováno v:
Blood. 78:838-843
One hundred twenty-seven patients with acute myelocytic leukemia (AML) were given busulfan 4 mg/kg on each of 4 days and cyclophosphamide 60 mg/kg on each of 2 days (BuCy2) followed by allogeneic bone marrow transplantation from an HLA-identical or o