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Akademický článek

Publikováno v: The Cryosphere, Vol 18, Pp 3471-3494 (2024)

Mapping sea ice in the Arctic is essential for maritime navigation, and growing vessel traffic highlights the necessity of the timeliness and accuracy of sea ice charts. In addition, with the increased availability of satellite imagery, automation is

Externí odkaz: https://doaj.org/article/ebd874885f5744c2984cbf65109ab89b

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Akademický článek

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Akademický článek

Genome Wide Identification of SARS-CoV Susceptibility Loci Using the Collaborative Cross.

Autor: Lisa E Gralinski, Martin T Ferris, David L Aylor, Alan C Whitmore, Richard Green, Matthew B Frieman, Damon Deming, Vineet D Menachery, Darla R Miller, Ryan J Buus, Timothy A Bell, Gary A Churchill, David W Threadgill, Michael G Katze, Leonard McMillan, William Valdar, Mark T Heise, Fernando Pardo-Manuel de Villena, Ralph S Baric

Publikováno v: PLoS Genetics, Vol 11, Iss 10, p e1005504 (2015)

New systems genetics approaches are needed to rapidly identify host genes and genetic networks that regulate complex disease outcomes. Using genetically diverse animals from incipient lines of the Collaborative Cross mouse panel, we demonstrate a gre

Externí odkaz: https://doaj.org/article/b8f7d6c3b6f74bfd8dd8a1fd634eea07

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Akademický článek

Modeling host genetic regulation of influenza pathogenesis in the collaborative cross.

Publikováno v: PLoS Pathogens, Vol 9, Iss 2, p e1003196 (2013)

Genetic variation contributes to host responses and outcomes following infection by influenza A virus or other viral infections. Yet narrow windows of disease symptoms and confounding environmental factors have made it difficult to identify polymorph

Externí odkaz: https://doaj.org/article/7b65541d5dda41df84e78d9a797b012a

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Does Upper Limb Coordination Predict Walking Speed in Older Adults? A Cross-Sectional Study

Autor: Kenzie L. Schleicher, Desiree J. Lanzino, John H. Hollman, Ryan J. Buus, Katherine C. Beed

Publikováno v: Journal of Geriatric Physical Therapy. 37:106-115

Background and purpose: Walking speed is a measure of physical function in older adults. Older adults are sometimes nonambulatory, however, and proxy measures for walking speed may be indicated. Since limb coordination tests can be conducted in non-w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af005d827bd82cde01d4432a39caa9c4
https://doi.org/10.1519/jpt.0b013e3182abe793

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A Novel Intronic Single Nucleotide Polymorphism in the Myosin heavy polypeptide 4 Gene Is Responsible for the Mini-Muscle Phenotype Characterized by Major Reduction in Hind-Limb Muscle Mass in Mice

Autor: George M. Weinstock, Scott A. Kelly, Kunjie Hua, Sarah R. Selitsky, Daniel Pomp, Timothy A. Bell, Fernando Pardo-Manuel de Villena, Ryan J. Buus, Theodore Garland

Publikováno v: Genetics. 195:1385-1395

Replicated artificial selection for high levels of voluntary wheel running in an outbred strain of mice favored an autosomal recessive allele whose primary phenotypic effect is a 50% reduction in hind-limb muscle mass. Within the High Runner (HR) lin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bba0767c6de92c0a851cd8532ce277ec
https://doi.org/10.1534/genetics.113.154476

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Identification of quantitative trait loci influencing skeletal architecture in mice: Emergence of Cdh11 as a primary candidate gene regulating femoral morphology

Autor: Daniel Yu, Daniel Pomp, Ryan J. Buus, Fernando Pardo-Manuel de Villena, Scott A. Kelly, Theodore Garland, Kunjie Hua, Derrick L. Nehrenberg, Charles R. Farber, Ethan M. Baruch

Publikováno v: Journal of Bone and Mineral Research. 26:2174-2183

Bone strength is influenced by many properties intrinsic to bone, including its mass, geometry, and mineralization. To further advance our understanding of the genetic basis of bone-strength-related traits, we used a large (n ¼ 815), moderately (G4)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e00529e7d0356187bfc3547da7128e85
https://doi.org/10.1002/jbmr.436

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Subspecific origin and haplotype diversity in the laboratory mouse

Autor: Pierre Boursot, Priscilla K. Tucker, John P. Didion, Alex Hon Tsen Yu, Jaroslav Piálek, Franãois Bonhomme, Ryan J. Buus, Michael W. Nachman, Leonard McMillan, Catherine E. Welsh, Jeremy Wang, Timothy A. Bell, Gary A. Churchill, Hyuna Yang, Fernando Pardo-Manuel de Villena

Publikováno v: Nature genetics
Nature Genetics
Nature Genetics, Nature Publishing Group, 2011, 43 (7), pp.648-655. ⟨10.1038/ng.847⟩
Nature Genetics, 2011, 43 (7), pp.648-655. ⟨10.1038/ng.847⟩

Here we provide a genome-wide, high-resolution map of the phylogenetic origin of the genome of most extant laboratory mouse inbred strains. Our analysis is based on the genotypes of wild-caught mice from three subspecies of Mus musculus. We show that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af26c0e6e47de225d1f483ca642b4f42
https://doi.org/10.1038/ng.847

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Akademický článek

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Inhibition of Apomorphine-Induced Climbing in Mice by Cholinergic Drugs and Neuroleptics

Autor: J. Buus Lassen

Publikováno v: Acta Pharmacologica et Toxicologica. 45:161-165

Apomorphine (ap) was administered subcutaneously to mice kept in individual cages. Ap elicited an abnormal vertical climbing behaviour. The muscarinomimetics physostigmine and oxotremorine as well as the neuroleptics clozapine and haloperidol inhibit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9250f98b0b72e6c79f15eccd35f562d8
https://doi.org/10.1111/j.1600-0773.1979.tb02376.x

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