Zobrazeno 1 - 10
of 172
pro vyhledávání: '"J. Brozmanová"'
Publikováno v:
Genetics and Molecular Biology, Vol 21, Iss 1 (1998)
Molecular and functional homology between yeast proteins pRad51 and pRad52 and Escherichia coli pRecA involved in recombinational DNA repair led us to investigate possible effects of recA gene expression on DNA repair in rad51 and rad52 mutants of Sa
Externí odkaz:
https://doaj.org/article/54f4af17730b410a866bb034973a293e
Publikováno v:
Archives of Toxicology. 84:919-938
Selenium (Se) is an essential dietary component for animals including humans and is regarded as a protective agent against cancer. Although the mode of anticancer action of Se is not fully understood yet, several mechanisms, such as antioxidant prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5f1293c58e6ddbb14894eb20b380d9c
https://doi.org/10.1007/s00204-010-0595-8
https://doi.org/10.1007/s00204-010-0595-8
Autor:
Eva Krascsenitsová, Dominika Mániková, Viera Vlčková, Lucia Letavayová, J. Brozmanová, Dana Vigasova, Danuša Vlasáková, Jana Loduhová, Miroslav Chovanec
Publikováno v:
Mutagenesis. 25:155-162
Selenium (Se) belongs to nutrients that are essential forhuman health. Biological activity of this compound, how-ever, mainly depends on its dose, with a potential of Se toinduce detrimental effects at high doses. Although mech-anisms lying behind de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a389f073a3bb22337e2cabf18dc28241
https://doi.org/10.1093/mutage/gep056
https://doi.org/10.1093/mutage/gep056
Publikováno v:
Toxicology. 227:1-14
Selenium (Se) is a dietary essential trace element with important biological roles. Accumulating evidence indicates that Se compounds possess anticancer properties. Se is specifically incorporated into proteins in the form of selenocysteine and non-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32de68be6e6ad13d193ed439772543a8
https://doi.org/10.1016/j.tox.2006.07.017
https://doi.org/10.1016/j.tox.2006.07.017
Autor:
Viera Vlčková, Lucia Letavayová, J. Brozmanová, Miroslav Chovanec, Eva Markova, Danuša Vlasáková, Katarína Hermanská
Publikováno v:
DNA Repair. 5:602-610
Oxidative damage to DNA seems to be an important factor in developing many human diseases including cancer. It involves base and sugar damage, base-free sites, DNA-protein cross-links and DNA single-strand (SSB) and double-strand (DSB) breaks. Oxidat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9e9d9f96bda3be0d5f5d0fd5e2e4583
https://doi.org/10.1016/j.dnarep.2006.01.004
https://doi.org/10.1016/j.dnarep.2006.01.004
Autor:
Miroslav Chovanec, Danuša Vlasáková, Milan Skorvaga, J. Brozmanová, Geoffrey P. Margison, L Cernáková, K. Kleibl, Jolyon H Hendry
Publikováno v:
International Journal of Radiation Biology. 79:747-755
To examine the contribution of endonuclease III (Nth)-repairable lesions to the cytotoxicity of ionizing radiation (IR) and hydrogen peroxide (H2O2) in the yeast Saccharomyces cerevisiae.A selectable expression vector containing the E. coli nth gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3378ee973f18d0c5a0c70e2d6a8b9efa
https://doi.org/10.1080/09553000310001606849
https://doi.org/10.1080/09553000310001606849
Autor:
Ada Kolman, Miroslav Chovanec, Eva Markova, Zdena Bartosova, Danuša Vlasáková, Andrej Dudáš, J. Brozmanová
Publikováno v:
Yeast. 20:389-396
The Saccharomyces cerevisiae rad52 mutants are sensitive to many DNA damaging agents, mainly to those that induce DNA double-strand breaks (DSBs). In the yeast, DSBs are repaired primarily by homologous recombination (HR). Since almost all HR events
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64a8fe9fd08b42dc651b4ea745c88df5
https://doi.org/10.1002/yea.971
https://doi.org/10.1002/yea.971
Publikováno v:
Folia Microbiologica. 44:587-624
Oxidative stress in microbial cells shares many similarities with other cell types but it has its specific features which may differ in prokaryotic and eukaryotic cells. We survey here the properties and actions of primary sources of oxidative stress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a38c09e21f2ff563bcb1b03079ac0388
https://doi.org/10.1007/bf02825650
https://doi.org/10.1007/bf02825650
Publikováno v:
Mutation Research/DNA Repair. 408:19-25
We have examined the hypersensitivity of Escherichia coli recA13 mutant cells to killing by N-methyl-N'-nitro-N-nitro-soguanidine (MNNG) and have shown out that despite MNNG-induced adaptation they remained vastly more sensitive to the cytotoxic effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec8637ac644b82360041c3fcfb783edd
https://doi.org/10.1016/s0921-8777(98)00014-7
https://doi.org/10.1016/s0921-8777(98)00014-7
Autor:
J. Brozmanová, João Antonio Pêgas Henriques, Viera Vlčková, M. Chovanec, Eva Farkašová, M. Nälund, Miroslava Slaninová
Publikováno v:
Folia Microbiologica. 40:257-262
Construction of E. coli-yeast shuttle plasmids containing the neo selection gene is described. The protein-coding regions of the E. coli ada or recA genes under the control of the ADH1 promoter and terminator were ligated into the SphI unique site of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dff9c6d47f34a29813a1cd29a24f410c
https://doi.org/10.1007/bf02814203
https://doi.org/10.1007/bf02814203