Zobrazeno 1 - 10
of 400
pro vyhledávání: '"J. Brochier"'
Publikováno v:
British journal of haematology. 114(2)
Human multiple myeloma (MM) purified tumour cells readily undergo apoptosis in vitro. Interleukin 6 (IL-6), a main growth factor of tumour cells, has enabled the development of IL-6-dependent MM cell lines. Recently, we developed anti-gp130 monoclona
Publikováno v:
European cytokine network. 10(3)
Interleukin-6 (IL-6) is used as a growth factor by various tumor cells. It binds to a gp80 specific receptor (IL-6R) and then to a gp130 transducing chain. Both receptor chains are released as soluble functional proteins which circulate in biological
Autor:
B, Klein, X Y, Li, Z Y, Lu, M, Jourdan, K, Tarte, J, Brochier, E, Claret, J, Wijdenes, J F, Rossi
Publikováno v:
Current topics in microbiology and immunology. 246
Publikováno v:
European cytokine network. 10(1)
Interleukin-6 (IL-6) is a major survival factor for malignant plasma cells. In patients with multiple myeloma (MM), cell lines whose survival and proliferation are dependent upon addition of exogenous IL-6 have been obtained. We show here that tumor
Publikováno v:
European cytokine network. 10(1)
Interleukin-6 (IL-6) is used as a growth factor by various tumor cells. It binds to a gp80 specific receptor (IL-6R) and then to a gp130 transducing chain. Both receptor chains are released as soluble functional proteins which circulate in biological
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 161(6)
IFN-alpha is used as a maintenance therapy in patients with multiple myeloma, but its benefit is a matter of controversy. In vitro studies show that IFN-alpha can both stimulate and inhibit myeloma cell proliferation. We have tested the effect of IFN
Autor:
M, Jourdan, M, Ferlin, E, Legouffe, M, Horvathova, J, Liautard, J F, Rossi, J, Wijdenes, J, Brochier, B, Klein
Publikováno v:
British journal of haematology. 100(4)
Syndecan-1 is a cell membrane proteoglycan that binds extracellular matrix components and various growth factors. It is expressed only on malignant plasma cells in bone marrow samples from patients with multiple myeloma (MM). Several reports have sug
Publikováno v:
Journal of clinical pathology. 50(10)
AIMS: Interleukin 6 (IL-6) is expressed in the majority of renal cell carcinomas and has an important role in the proliferation of some renal cell carcinoma cell lines. This action is mediated by two membrane proteins, gp80 (the IL-6 receptor; IL-6R)
Publikováno v:
Clinical and experimental immunology. 106(1)
The aim of this study was to assess regulation of mononuclear cell (MNC) traffic to human synovial tissue by TNF-alpha and IL-1 and the involvement of ICAM-1 in MNC retention in rheumatoid synovial tissue. Human rheumatoid arthritis synovium was engr
Publikováno v:
Clinical and experimental rheumatology. 14(3)
To study the clinical, biological and radiological characteristics of RA with a predominant increase of IgA isotype rheumatoid factor (IgA-RF) over IgM-RF.The presence of IgA-RF was determined by a sandwich-type ELISA with an antibody against the hum