Zobrazeno 1 - 10
of 776
pro vyhledávání: '"J. Bristow"'
Autor:
Nina Dedic, Lien Wang, Eva Hajos-Korcsok, Jacob Hecksher-Sørensen, Urmas Roostalu, Steven P. Vickers, Serena Wu, Christoph Anacker, Colleen Synan, Philip G. Jones, Snezana Milanovic, Seth C. Hopkins, Linda J. Bristow, Kenneth S. Koblan
Publikováno v:
Molecular Metabolism, Vol 80, Iss , Pp 101883- (2024)
Objective: Metabolic Syndrome, which can be induced or exacerbated by current antipsychotic drugs (APDs), is highly prevalent in schizophrenia patients. Recent preclinical and clinical evidence suggest that agonists at trace amine-associated receptor
Externí odkaz:
https://doaj.org/article/b7fe5a8971f046fa9b051d0ee080c127
Autor:
Brian R. Anderson, Marianne L. Jensen, Peter H. Hagedorn, Sean C. Little, Richard E. Olson, Ron Ammar, Bernadette Kienzle, John Thompson, Ivar McDonald, Stephen Mercer, Jonas Vikesaa, Bettina Nordbo, Larry Iben, Yang Cao, Joanne Natale, Greg Dalton-Kay, Angela Cacace, Bo R. Hansen, Maj Hedtjärn, Troels Koch, Linda J. Bristow
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 19, Iss , Pp 1290-1298 (2020)
Hundreds of dominant-negative myosin mutations have been identified that lead to hypertrophic cardiomyopathy, and the biomechanical link between mutation and disease is heterogeneous across this patient population. To increase the therapeutic feasibi
Externí odkaz:
https://doaj.org/article/ebaf673f331045b1903490834433fa8c
Autor:
Lora J. Bristow
Publikováno v:
Humboldt Journal of Social Relations. 1:146-148
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8ab8c9ea4a41052b834ac1de5fb0eca
https://doi.org/10.55671/0160-4341.1193
https://doi.org/10.55671/0160-4341.1193
Autor:
Michael R Weed, Joseph Polino, Laura Signor, Mark Bookbinder, Deborah Keavy, Yulia Benitex, Daniel G Morgan, Dalton King, John E Macor, Robert Zaczek, Richard Olson, Linda J Bristow
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0187609 (2017)
Agonists at the nicotinic acetylcholine alpha 7 receptor (nAChR α7) subtype have the potential to treat cognitive deficits in patients with Alzheimer's disease (AD) or schizophrenia. Visuo-spatial paired associates learning (vsPAL) is a task that ha
Externí odkaz:
https://doaj.org/article/7092e6186ae346de8340928c86171e4b
Autor:
Nina Dedic, Philip G. Jones, Eva Hajos-Korcsok, Colleen Synan, Serena Wu, Christoph Anacker, Steve P. Vickers, Jacob Hecksher-Sørensen, Courtney Zeni, Snezana Milanovic, Seth C. Hopkins, Linda J. Bristow, Kenneth S. Koblan
Publikováno v:
CNS Spectrums. 28:259-259
IntroductionPreclinical evidence has identified the trace amine-associated receptor 1 (TAAR1) as a novel regulator of metabolic control. Ulotaront is a TAAR1 and 5-HT1A agonist currently in Phase 3 clinical trials for the treatment of schizophrenia.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::225a940737db1f6bfc2cae7a1a081c59
https://doi.org/10.1017/s1092852923002079
https://doi.org/10.1017/s1092852923002079
Publikováno v:
Journal of Attention Disorders
Objective: To synthesize the evidence on the efficacy of ADHD teacher training interventions for teachers’ ADHD knowledge and reducing pupils’ ADHD-type behaviors. Method: Six electronic databases were systematically searched up to 14/04/20. Meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7683d1fe77fcb47cca86a8a6f3990ac1
https://doi.org/10.1177/1087054720972801
https://doi.org/10.1177/1087054720972801
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Autor:
Linda J Bristow, Amy E Easton, Yu-Wen Li, Digavalli V Sivarao, Regina Lidge, Kelli M Jones, Debra Post-Munson, Christopher Daly, Nicholas J Lodge, Lizbeth Gallagher, Thaddeus Molski, Richard Pieschl, Ping Chen, Adam Hendricson, Ryan Westphal, James Cook, Christiana Iwuagwu, Daniel Morgan, Yulia Benitex, Dalton King, John E Macor, Robert Zaczek, Richard Olson
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159996 (2016)
The development of alpha7 nicotinic acetylcholine receptor agonists is considered a promising approach for the treatment of cognitive symptoms in schizophrenia patients. In the present studies we characterized the novel agent, (2R)-N-(6-(1H-imidazol-
Externí odkaz:
https://doaj.org/article/cb2d80cbb97446c297511d2d30823d16
Autor:
Deborah Keavy, Linda J Bristow, Digavalli V Sivarao, Margaret Batchelder, Dalton King, Srinivasan Thangathirupathy, John E Macor, Michael R Weed
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0152729 (2016)
The antidepressant activity of the N-methyl-D-aspartate (NMDA) receptor channel blocker, ketamine, has led to the investigation of negative allosteric modulators (NAMs) selective for the NR2B receptor subtype. The clinical development of NR2B NAMs wo
Externí odkaz:
https://doaj.org/article/4fb081f3921e4d76b643f063687b31cb
Autor:
Bo Hansen, Brian R. Anderson, Linda J. Bristow, Jonas Vikesaa, Sean C. Little, JoAnne E Natale, Maj Hedtjarn, Greg Dalton-Kay, John Ryan Thompson, Yang Cao, Peter Hagedorn, Marianne Lerbech Jensen, Ivar M. McDonald, Bernadette Kienzle, Larry Iben, Stephen E. Mercer, Bettina Nordbo, Angela Cacace, Troels Koch, Richard E. Olson, Ron Ammar
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 19, Iss, Pp 1290-1298 (2020)
Molecular Therapy. Nucleic Acids
Molecular Therapy. Nucleic Acids
Hundreds of dominant-negative myosin mutations have been identified that lead to hypertrophic cardiomyopathy, and the biomechanical link between mutation and disease is heterogeneous across this patient population. To increase the therapeutic feasibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::939dd82832ab3389515df63ef0ae4e69
http://www.sciencedirect.com/science/article/pii/S2162253120300470
http://www.sciencedirect.com/science/article/pii/S2162253120300470