Zobrazeno 1 - 10
of 288
pro vyhledávání: '"J. Breunig"'
Autor:
Emily A. Hatanaka, Joshua J. Breunig
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Ependymomas are rare brain tumors that can occur in both children and adults. Subdivided by the tumors’ initial location, ependymomas develop in the central nervous system in the supratentorial or infratentorial/posterior fossa region, or the spina
Externí odkaz:
https://doaj.org/article/b7c836d1f04649dea07e86982669f055
Publikováno v:
Frontiers in Oncology, Vol 13 (2024)
Pediatric low-grade gliomas represent the most common childhood brain tumor class. While often curable, some tumors fail to respond and even successful treatments can have life-long side effects. Many clinical trials are underway for pediatric low-gr
Externí odkaz:
https://doaj.org/article/b551ec4101c14035887d23ae0d75c117
Autor:
Robert M Prins, Katie B Grausam, Joshua J Breunig, Marissa S Pioso, Marissa Li, David A Nathanson
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/4b17f30236a6427288c29029fbd47557
Autor:
Katie B Grausam, Emily Hatanaka, Tahir B Dar, David Rincon Fernandez Pacheco, Joshua J Breunig, Stephen L Shiao
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/fb97104d937f4788abd65ef693233a34
Autor:
Antonio C. Fuentes-Fayos, Jesús M. Pérez-Gómez, Miguel E. G-García, Juan M. Jiménez-Vacas, Cristóbal Blanco-Acevedo, Rafael Sánchez-Sánchez, Juan Solivera, Joshua J. Breunig, Manuel D. Gahete, Justo P. Castaño, Raúl M. Luque
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-23 (2022)
Abstract Background Glioblastoma is one of the most devastating cancer worldwide based on its locally aggressive behavior and because it cannot be cured by current therapies. Defects in alternative splicing process are frequent in cancer. Recently, w
Externí odkaz:
https://doaj.org/article/302009fc920f44f29ce38b09cfabbfd1
Autor:
Huy Q. Dinh, Feng Pan, Geng Wang, Qing-Feng Huang, Claire E. Olingy, Zhi-Yong Wu, Shao-Hong Wang, Xin Xu, Xiu-E Xu, Jian-Zhong He, Qian Yang, Sandra Orsulic, Marcela Haro, Li-Yan Li, Guo-Wei Huang, Joshua J. Breunig, H. Phillip Koeffler, Catherine C. Hedrick, Li-Yan Xu, De-Chen Lin, En-Min Li
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
The microenvironment of oesophageal squamous cell carcinomas (ESCC) is heterogeneous and can strongly impact response to treatment. Here, the authors characterize the ESCC tumour microenvironment with single-cell RNA-seq, finding CST1 + myofibroblast
Externí odkaz:
https://doaj.org/article/2e80dc52b5e14a5c9cab19a0f4a82e35
Autor:
Ping Shi, Jia Tian, Julianne C. Mallinger, Dahao Ling, Loic P. Deleyrolle, Jeremy C. McIntyre, Tamara Caspary, Joshua J. Breunig, Matthew R. Sarkisian
Publikováno v:
Cells, Vol 12, Iss 19, p 2354 (2023)
ADP-ribosylation factor-like protein 13B (ARL13B), a regulatory GTPase and guanine exchange factor (GEF), enriches in primary cilia and promotes tumorigenesis in part by regulating Smoothened (SMO), GLI, and Sonic Hedgehog (SHH) signaling. Gliomas wi
Externí odkaz:
https://doaj.org/article/4ecbb8232b484655acc6682a38159c39
Autor:
Gustavo Garcia, Nikhil Chakravarty, Sophia Paiola, Estrella Urena, Priya Gyani, Christopher Tse, Samuel W. French, Moise Danielpour, Joshua J. Breunig, David A. Nathanson, Vaithilingaraja Arumugaswami
Publikováno v:
Cells, Vol 12, Iss 19, p 2384 (2023)
Glioblastoma (GBM), the most common primary malignant brain tumor, is a highly lethal form of cancer with a very limited set of treatment options. High heterogeneity in the tumor cell population and the invasive nature of these cells decrease the lik
Externí odkaz:
https://doaj.org/article/8926c3d6d90e4bebaeeb5b891a2f0d6c
Publikováno v:
STAR Protocols, Vol 1, Iss 3, Pp 100184- (2020)
Summary: Mosaic analysis by dual recombinase-mediated cassette exchange (MADR) is a technology that allows stable and locus-specific integration of transgenic elements into recipient cells carrying loxP and FRT sites. Nevertheless, most cell lines la
Externí odkaz:
https://doaj.org/article/14e116ee955e41a0be6b792398a964c1
Publikováno v:
STAR Protocols, Vol 1, Iss 3, Pp 100199- (2020)
Summary: This protocol focuses on the cloning and stable integration of sequences of interest by the use of a mosaic analysis with dual recombinases (MADR) plasmid that includes fusion proteins or independent proteins under the control of 2A peptide
Externí odkaz:
https://doaj.org/article/310f92108b4742e7b8bd9d49fcfacaec