Zobrazeno 1 - 10
of 98
pro vyhledávání: '"J. Brecht"'
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Tinnitus is the phantom perception of sound that has no external source. A neurological signature of tinnitus, and the frequently associated hyperacusis, is an imbalance between excitatory and inhibitory activity in the central auditory system (CAS),
Externí odkaz:
https://doaj.org/article/0f63544f12704db1aac11bf3932d80c5
Publikováno v:
Neurobiology of aging. 110
Recent evidence suggests that modulation of the large-conductance, calcium-activated potassium (BK) channel regulates auditory processing in the brain. Because ion channel expression often changes during aging, this could be a factor in age-related h
Publikováno v:
EDIS, Vol 2004, Iss 8 (2004)
Tropical spiderwort is an aggressive weed that produces aerial (above ground) and subterranean (below ground) flowers. This results in viable seed being produced both above and below ground. Tropical spiderwort also possesses the ability to root at t
Externí odkaz:
https://doaj.org/article/378c313477be4aee99444bb811d9759a
Publikováno v:
Neurobiology of Aging. 56:87-99
A key feature of age-related hearing loss is a reduction in the expression of inhibitory neurotransmitters in the central auditory system. This loss is partially responsible for changes in central auditory processing, as inhibitory receptive fields p
Publikováno v:
Journal of Materials Processing Technology. 229:139-148
Continuously increasing demands for consumption-optimized automotive concepts require steady development of weight-saving potentials. In the area of steel lightweight design, flexible rolling of tailor-rolled blanks, TRB, is a well-established techno
Publikováno v:
Acta Horticulturae. :459-464
The current Florida peach industry is predominantly located in a subtropical climate, and fertilization regimes developed in temperate climates may not fulfill the nutritional demand for extended postharvest vegetative growth. The objective of this r
Autor:
Jonathan T. Pierce, S. J. Mihic, Ashley E. Philpo, Elliott J. Brecht, Luisa L. Scott, Sangeetha Iyer, N. S. Wu, Richard W. Aldrich, Joseph P. Walton
Publikováno v:
Scientific Reports
Large conductance calcium-activated (BK) channels are broadly expressed in neurons and muscle where they modulate cellular activity. Decades of research support an interest in pharmaceutical applications for modulating BK channel function. Here we re
Autor:
Katsuhiko Yanagisawa, Hui Zhang, Walter J. Brecht, Makoto Michikawa, Yadong Huang, Jacob Corn, Tony Wyss-Coray, Ina Tesseur, Karl H. Weisgraber, Jian-Sheng Gong
Publikováno v:
Journal of Neurochemistry. 110:1254-1262
Transforming growth factor-beta1 (TGF-beta1) has central functions in development, tissue maintenance, and repair and has been implicated in major diseases. We discovered that TGF-beta1 contains several amphipathic helices and hydrophobic domains sim
Publikováno v:
Gesundheitsökonomie & Qualitätsmanagement. 11:292-301
Publikováno v:
Journal of Biological Chemistry. 279:44795-44801
Although apolipoprotein (apo) E4 is present in amyloid plaques and neurofibrillary tangles, its pathogenic role in Alzheimer's disease (AD) is unclear. Neuronal expression of apoE4 or apoE4 fragments in transgenic mice increases tau phosphorylation.