Novel Zoonotic Avian Influenza A(H3N8) Virus in Chicken, Hong Kong, China

Autor: Thomas H.C. Sit, Wanying Sun, Anne C.N. Tse, Christopher J. Brackman, Samuel M.S. Cheng, Amy W. Yan Tang, Jonathan T.L Cheung, Malik Peiris, Leo L.M. Poon

Publikováno v: Emerging Infectious Diseases, Vol 28, Iss 10, Pp 2009-2015 (2022)

Zoonotic and pandemic influenza continue to pose threats to global public health. Pandemics arise when novel influenza A viruses, derived in whole or in part from animal or avian influenza viruses, adapt to transmit efficiently in a human population

Externí odkaz: https://doaj.org/article/21e04b799d7c43168e55e8e42d97e31b

SARS-CoV-2 in Quarantined Domestic Cats from COVID-19 Households or Close Contacts, Hong Kong, China

Autor: Vanessa R. Barrs, Malik Peiris, Karina W.S. Tam, Pierra Y.T. Law, Christopher J. Brackman, Esther M.W. To, Veronica Y.T. Yu, Daniel K.W. Chu, Ranawaka A.P.M. Perera, Thomas H.C. Sit

Publikováno v: Emerging Infectious Diseases, Vol 26, Iss 12, Pp 3071-3074 (2020)

We tested 50 cats from coronavirus disease households or close contacts in Hong Kong, China, for severe acute respiratory syndrome coronavirus 2 RNA in respiratory and fecal samples. We found 6 cases of apparent human-to-feline transmission involving

Externí odkaz: https://doaj.org/article/bcf654683a4341ecb31926a2335f8a66

Amine-Functionalized Quantum Dots as a Universal Fluorescent Nanoprobe for a One-Step Loop-Mediated Isothermal Amplification Assay with Single-Copy Sensitivity

Autor: Shiyao Wang, Ailin Qin, Li Yin Chau, Eunice W. T. Fok, Mei Yue Choy, Christopher J. Brackman, Gilman K. H. Siu, Chien-Ling Huang, Shea Ping Yip, Thomas M. H. Lee

Publikováno v: ACS Applied Materials & Interfaces. 14:35299-35308

Loop-mediated isothermal amplification (LAMP) has received considerable attention for decentralized (point-of-care and on-site) nucleic acid testing in view of its simple temperature control (60-65 °C) and short assay time (15-60 min). There remains

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::253241b679bc58bdf3df28021aacb572
https://doi.org/10.1021/acsami.2c02508

Transmission of SARS-CoV-2 delta variant (AY.127) from pet hamsters to humans, leading to onward human-to-human transmission: a case study

Autor: Hui-Ling Yen, Thomas H C Sit, Christopher J Brackman, Shirley S Y Chuk, Haogao Gu, Karina W S Tam, Pierra Y T Law, Gabriel M Leung, Malik Peiris, Leo L M Poon, Samuel M S Cheng, Lydia D J Chang, Pavithra Krishnan, Daisy Y M Ng, Gigi Y Z Liu, Mani M Y Hui, Sin Ying Ho, Wen Su, Sin Fun Sia, Ka-Tim Choy, Sammi S Y Cheuk, Sylvia P N Lau, Amy W Y Tang, Joe C T Koo, Louise Yung

Publikováno v: The Lancet. 399:1070-1078

Transmission of SARS-CoV-2 from humans to other mammals, including pet animals, has been reported. However, with the exception of farmed mink, there is no previous evidence that these infected animals can infect humans, resulting in sustained human-t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a113603c3dfff2c72df7f4d385202f4
https://doi.org/10.1016/s0140-6736(22)00326-9

Oxypurinol pharmacokinetics and pharmacodynamics in healthy volunteers: Influence of BCRP Q141K polymorphism and patient characteristics

Autor: Marina Sirota, Radojka M. Savic, Deanna J. Brackman, Kathleen M. Giacomini, Maria Garcia-Cremades, Ling Zou, Bianca Vora

Publikováno v: Clinical and Translational Science, Vol 14, Iss 4, Pp 1431-1443 (2021)
Clinical and Translational Science
Clinical and translational science, vol 14, iss 4

The missense variant, breast cancer resistance protein (BCRP) p.Q141K, which encodes a reduced function BCRP, has been linked to poor response to allopurinol. Using a multifaceted approach, we aimed to characterize the relationship(s) between BCRP p.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42d4c82d3a2e0212181aa9a5a1be7afb
https://doaj.org/article/98b41c06c2c44475a26d2040c01b000c