Zobrazeno 1 - 10
of 168
pro vyhledávání: '"J. Borovanský"'
Publikováno v:
Melanoma Research. 8:39-45
The total serum activity of gamma-glutamyl transpeptidase (GGT) was shown to increase with the growth of transplantable B16 and S91 melanomas in inbred mice. In an effort to define the source of the GGT shed into the bloodstream the physicochemical c
Autor:
N. P. M. Smit, A. Mieke Mommaas, J. Borovanský, Denise Eygendaal, Stan Pavel, A. J. Winder, Bert J. Vermeer
Publikováno v:
Archives of Dermatological Research. 289:145-150
Normal melanosome biogenesis requires the association of structural proteins with tyrosinase. 3T3 Swiss fibroblasts transfected with mouse tyrosinase cDNA (line 13.4, clone c) are a unique system in which melanogenesis takes place in the absence of m
Autor:
J, Vachtenheim, J, Borovanský
Publikováno v:
Prague medical report. 105(3)
The transcription factor microphthalmia (MITF) is required for the formation of normal melanocytes during embryonic development and for the expression of pigment cell-specific markers, which are the downstream transcriptional targets of MITF. It also
Autor:
M, Elleder, J, Borovanský
Publikováno v:
The Histochemical journal. 33(5)
The induction of autofluorescence of melanins by UV radiation (330-380 nm) and near UV (400-440 nm) light (jointly called UV light) was studied in tissue sections using three commercially available mounting media. Only Immu-Mount (Shandon) was found
Publikováno v:
Sbornik lekarsky. 101(2)
"Leucine aminopeptidase" (LAP, aminopolypeptidase, EC 3.4.11) activity has been recommended and widely used as a histochemical marker for the identification of contaminating LAP-positive fibroblasts in pigment cell cultures. Using a sensitive biochem
Publikováno v:
Folia biologica. 45(2)
Contradiction between repeatedly reported electron microscopic and histochemical observation of melanosome disintegration in the presence of lysosomal enzymes in vivo and failing attempts to induce such degradation by biochemical means in vitro with
Autor:
J, Borovanský, P, Hach
Publikováno v:
Cellular and molecular biology (Noisy-le-Grand, France). 45(7)
In addition to tyrosinase and its related proteins melanosomes contain a variety of further enzyme activities. Using spectrophotometric methods alpha-mannosidase and gamma-glutamyl-transferase (GGT) were studied in B 16 melanoma, in isolated melanoso
Publikováno v:
Melanoma research. 8(1)
The total serum activity of gamma-glutamyl transpeptidase (GGT) was shown to increase with the growth of transplantable B16 and S91 melanomas in inbred mice. In an effort to define the source of the GGT shed into the bloodstream the physicochemical c
Publikováno v:
Melanoma research. 7(6)
Previous studies have shown that sensitivity to high extracellular levels of Zn2+ is a general feature of cells in vitro and that a prerequisite of the toxic action of zinc is entry into cells via channels that are shared with iron or calcium. As the
Autor:
J, Borovanský
Publikováno v:
Sbornik lekarsky. 98(2)
The current state of art in the detection of metals in tissues, cells and their subcellular fractions has been reviewed. Both classic chemical techniques (including titration, spectrophotometric, electrochemical and isotope methods, neutron activatio