Zobrazeno 1 - 10
of 74
pro vyhledávání: '"J. Bole"'
Publikováno v:
Polar Organometallic Reagents. :271-316
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::344cab19a4956d4e50f386a632dacd2b
https://doi.org/10.1002/9781119448877.ch6
https://doi.org/10.1002/9781119448877.ch6
Autor:
Andreu Tortajada, Leonie J. Bole, Manting Mu, Martin Stanford, Marconi N. Peñas-Defrutos, Max García-Melchor, Eva Hevia
Producción Científica
The deprotonative metalation of organic molecules has become a convenient route to prepare functionalised aromatic substrates. Amongst the different metallating reagents available, sodium bases have recently emerged as a
The deprotonative metalation of organic molecules has become a convenient route to prepare functionalised aromatic substrates. Amongst the different metallating reagents available, sodium bases have recently emerged as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3386ba4c5dbef0c2535648666af1d151
https://doi.org/10.1039/d3sc01705b
https://doi.org/10.1039/d3sc01705b
Autor:
Leonie J. Bole, Alberto Hernán-Gómez, Alan R. Kennedy, Marina Uzelac, Charles T. O'Hara, Eva Hevia
Publikováno v:
Inorganic Chemistry. 60:13784-13796
Exploiting the steric incompatibility of the tris-(alkyl)gallium GaR3 (R = CH2SiMe3) and the bulky N-heterocyclic carbene (NHC) 1,3-bis(tert-butyl)imidazol-2-ylidene (ItBu), here we report the B−H bond activation of pinacolborane (HBPin), which has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a50d7713d732639f2e4820f512b9eff
https://doi.org/10.1021/acs.inorgchem.1c01276
https://doi.org/10.1021/acs.inorgchem.1c01276
Autor:
Alexander Kremsmair, Alisa S. Sunagatullina, Leonie J. Bole, Pasquale Mastropierro, Simon Graßl, Henrik R. Wilke, Edouard Godineau, Eva Hevia, Paul Knochel
Publikováno v:
Kremsmair, Alexander; Sunagatullina, Alisa S.; Bole, Leonie J; Mastropierro, Pasquale; Graßl, Simon; Wilke, Henrik R.; Godineau, Edouard; Hevia, Eva; Knochel, Paul (2022). Exploiting Coordination Effects for the Regioselective Zincation of Diazines Using TMPZnX⋅LiX (X=Cl, Br). Angewandte Chemie International Edition, 61(40), e202210491. GDCh 10.1002/anie.202210491
A new method for regioselective zincations of challenging N-heterocyclic substrates such as pyrimidines and pyridazine was reported using bimetallic bases TMPZnX⋅LiX (TMP=2,2,6,6-tetramethylpiperidyl; X=Cl, Br). Reactions occurred under mild condit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07aa595137d1137781e7dbea5860be74
https://pubmed.ncbi.nlm.nih.gov/35943036
https://pubmed.ncbi.nlm.nih.gov/35943036
Publikováno v:
Angewandte Chemie International Edition. 60:7626-7631
While it is known that the addition of Group 1 alkoxides to s-block organometallics can have an activating effect on reactivity, the exact nature of this effect is not that well understood. Here we describe the activation of sBu2 Mg towards substitut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73f94ae8afe40c5f51aa88abffefa1bc
https://doi.org/10.1002/anie.202016422
https://doi.org/10.1002/anie.202016422
Publikováno v:
Desaintjean, Alexandre; Haupt, Tobias; Bole, Leonie J.; Judge, Neil R.; Hevia, Eva; Knochel, Paul (2021). Regioselective Bromine/Magnesium Exchange for the Selective Functionalization of Polyhalogenated Arenes and Heterocycles. Angewandte Chemie (International ed.), 60(3), pp. 1513-1518. Wiley-VCH 10.1002/anie.202012496
Angewandte Chemie (International Ed. in English)
Angewandte Chemie (International Ed. in English)
Using the bimetallic combination sBu2Mg⋅2 LiOR (R=2‐ethylhexyl) in toluene enables efficient and regioselective Br/Mg exchanges with various dibromo‐arenes and ‐heteroarenes under mild reaction conditions and provides bromo‐substituted magn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::579c0e7e3be12be5a09fe95dce01f83d
https://doi.org/10.1002/anie.202012496
https://doi.org/10.1002/anie.202012496
Publikováno v:
Angewandte Chemie. 133:1536-1541
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78169e5b83458a840710ff00823cafc8
https://doi.org/10.1002/ange.202012496
https://doi.org/10.1002/ange.202012496
Publikováno v:
Judge, Neil R.; Bole, Leonie J.; Hevia, Eva (2022). Assessing Alkali-Metal Effects in the Structures and Reactivity of Mixed-Ligand Alkyl/Alkoxide Alkali-Metal Magnesiates. Chemistry-a European journal, 28(10), e202104164. Wiley-VCH 10.1002/chem.202104164
Advancing the understanding of using alkali-metal alkoxides as additives to organomagnesium reagents in Mg-Br exchange reactions, a homologous series of mixed-ligand alkyl/alkoxide alkali-metal magnesiates [MMg(CH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae934bef280e846178b16310dcf5b626
https://pubmed.ncbi.nlm.nih.gov/34939701
https://pubmed.ncbi.nlm.nih.gov/34939701
Autor:
Alexandre Desaintjean, Paul Knochel, Eva Hevia, Dorothée Ziegler, Moritz Balkenhohl, Alan R. Kennedy, Leonie J. Bole
Publikováno v:
Angewandte Chemie. 131:13030-13034
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1270f6039a47a20b4214a61a312097f3
https://doi.org/10.1002/ange.201906898
https://doi.org/10.1002/ange.201906898
Publikováno v:
Chemical Communications. 55:4339-4342
A series of new Mg(ii) amides featuring a bulky β-diketiminate backstop ligand, has been synthesised. These complexes are demonstrated to be excellent sources of nucleophilic amides that can participate in rapid C-F activation of several fluoroarene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c970ea169cbc9ba6ec5a36f2285009a5
https://doi.org/10.1039/c9cc01670h
https://doi.org/10.1039/c9cc01670h