Zobrazeno 1 - 10
of 176
pro vyhledávání: '"J. Belehradek"'
Autor:
Lluis M. Mir, Gregor Sersa, Maja Cemazar, J. Belehradek, Marc Bonnay, Damijan Miklavčič, D Fourcault
Publikováno v:
European Journal of Cancer. 37:1166-1172
The aim of the study was to determine whether electrochemotherapy with cisplatin could be implemented in treatment of cisplatin-resistant solid tumours. For this purpose, we used cisplatin-sensitive TBL.Cl2 cells and their cisplatin-resistant subclon
Publikováno v:
Anti-Cancer Drugs. 9:551-556
Murine Lewis lung (3LL) tumors are characterized by the appearance of lung metastases after a regular period following their s.c. transplantation. We tested the respective efficiencies of various antitumor treatments: (i) electrochemotherapy (ECT), i
Publikováno v:
Bioelectrochemistry and Bioenergetics. 43:253-256
A single-shot electrotherapy with 0,6 rnA direct current for 60 minutes delivered via two needle electrodes placed subcutaneously on opposite sides of a tumor induced statistically significant tumor growth delay in SA-l and LPB murine fibrosarcoma tu
Autor:
Lluis M. Mir, F. Delisle, S. Doliger, Didier Fradelizi, J. Belehradek, F. Quintin-Colonna, Stéphane Orlowski, P. Devauchelle
Publikováno v:
British Journal of Cancer
Electrochemotherapy combines bleomycin and local electric pulses that allow cell permeabilization and free access of bleomycin to its intracellular target. We report the first veterinarian clinical trial of electrochemotherapy in 12 cats with spontan
Autor:
Marie-Pierre Rols, J. Belehradek, Damijan Miklavčič, Justin Teissié, Stéphane Orlowski, Richard Gilbert, Richard Heller, Gregor Sersa, Lluis M. Mir
Publikováno v:
Bioelectrochemistry and Bioenergetics. 38:203-207
Short and intense electric pulses (EP) are regularly used in almost all molecular and cellular biology laboratories to introduce foreign DNA, as well as other exogeneous molecules, into living cells. Besides these in vitro applications, some in vivo
Autor:
B Psaume, JM Saucier, M Monnot, Violaine Simon, Jr J Belehradek, O Mauffret, E Lescot, S Fermandjian, Monique Charra
Publikováno v:
Journal of Biological Chemistry. 266:1820-1829
Cytotoxic effects and topoisomerase II-mediated DNA breaks induced in vitro by ellipticine derivatives were examined in connection with 1H NMR and circular dichroism (CD) studies on molecular structures and interactions of drugs with DNA. The compoun
Publikováno v:
European Journal of Cancer and Clinical Oncology. 27:73-76
Electrochemotherapy delivers external electric pulses to the tumour site to induce local potentiation of the antitumour activity of intramuscular injections of bleomycin. C3H/Bi mice with spontaneous mammary carcinomas received weekly injections of 5
Publikováno v:
European journal of cancer (Oxford, England : 1990). 37(9)
The aim of the study was to determine whether electrochemotherapy with cisplatin could be implemented in treatment of cisplatin-resistant solid tumours. For this purpose, we used cisplatin-sensitive TBL.Cl2 cells and their cisplatin-resistant subclon
Publikováno v:
Cancer biochemistry biophysics. 16(1-2)
P-glycoprotein (P-gp), a plasma membrane glycoprotein associated with the multidrug resistance phenotype, is responsible for the ATP-dependent efflux of various amphiphilic drugs. Using membrane vesicles prepared from the multidrug resistant cell lin
Publikováno v:
European cytokine network. 8(3)
Electrotherapy by low level direct current has been demonstrated to have antitumor effects in different murine tumor models and in clinics. Electrotherapy in "field" configuration, where electrodes are placed subcutaneously outside of the tumor in a