Zobrazeno 1 - 10
of 646
pro vyhledávání: '"J. Beesley"'
Autor:
George E. Ronson, Katarzyna Starowicz, Elizabeth J. Anthony, Ann Liza Piberger, Lucy C. Clarke, Alexander J. Garvin, Andrew D. Beggs, Celina M. Whalley, Matthew J. Edmonds, James F. J. Beesley, Joanna R. Morris
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract A synthetic lethal relationship exists between disruption of polymerase theta (Polθ), and loss of either 53BP1 or homologous recombination (HR) proteins, including BRCA1; however, the mechanistic basis of these observations are unclear. Her
Externí odkaz:
https://doaj.org/article/9fe50622466f46da85132eed80fe32f1
Autor:
Kathryn W Hendrickson, Meghan M Cirulis, Rebecca E Burk, Michael J Lanspa, Ithan D Peltan, Hunter Marshall, Danielle Groat, Al Jephson, Sarah J Beesley, Samuel M Brown
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0299876 (2024)
IntroductionSeptic shock is a severe form of sepsis that has a high mortality rate, and a substantial proportion of these patients will develop cardiac dysfunction, often termed septic cardiomyopathy (SCM). Some SCM patients may develop frank cardiac
Externí odkaz:
https://doaj.org/article/8b2afe9580884cdc85f1ddb72bc8368b
Autor:
E. J. Zirnstein, T. K. Kim, J. S. Rankin, M. A. Dayeh, D. J. McComas, P. Swaczyna, L. J. Beesley, D. B. Reisenfeld
Publikováno v:
The Astrophysical Journal, Vol 974, Iss 2, p 213 (2024)
Interstellar Boundary Explorer (IBEX) observations of energetic neutral atom (ENA) fluxes from the heliosphere have greatly enriched our understanding of the interaction of the solar wind (SW) with the local interstellar medium (LISM). However, there
Externí odkaz:
https://doaj.org/article/4d010e90f0724cc09f4e1370410aea52
Autor:
Kelly R. Moran, Dave Osthus, Brian P. Weaver, Lauren J. Beesley, Madeline A. Stricklin, Paul H. Janzen, Daniel B. Reisenfeld
Publikováno v:
The Astrophysical Journal, Vol 969, Iss 2, p 166 (2024)
Space scientists often face the question of whether data collected by different instruments are measurements of the same source population. This paper proposes a statistical validation method for evaluating the agreement between such related data set
Externí odkaz:
https://doaj.org/article/f568db39ba6d43e88b2ddf1615628eb2
Autor:
D. J. McComas, M. Alimaganbetov, L. J. Beesley, M. Bzowski, H. O. Funsten, P. H. Janzen, M. A. Kubiak, J. S. Rankin, D. B. Reisenfeld, N. A. Schwadron, J. R. Szalay
Publikováno v:
The Astrophysical Journal Supplement Series, Vol 270, Iss 2, p 17 (2024)
The Interstellar Boundary Explorer (IBEX) has been observing the outer heliosphere and its interactions with the very local interstellar medium (VLISM) via measurements of energetic neutral atoms (ENAs) for over 14 yr. We discovered the IBEX Ribbon
Externí odkaz:
https://doaj.org/article/81d31aa8f9cc4b21bf1bcaad83062785
Autor:
Madeline R Abbott, Lauren J Beesley, Emily L Bellile, Andrew G Shuman, Laura S Rozek, Jeremy M G Taylor
Publikováno v:
Cancer Informatics, Vol 22 (2023)
Background: In recent years, interest in prognostic calculators for predicting patient health outcomes has grown with the popularity of personalized medicine. These calculators, which can inform treatment decisions, employ many different methods, eac
Externí odkaz:
https://doaj.org/article/3f5b633bab184c0cb9758a452da2c330
Autor:
Lauren J. Beesley, Kelly R. Moran, Kshitij Wagh, Lauren A. Castro, James Theiler, Hyejin Yoon, Will Fischer, Nick W. Hengartner, Bette Korber, Sara Y. Del Valle
Publikováno v:
EBioMedicine, Vol 91, Iss , Pp 104534- (2023)
Summary: Background: Throughout the COVID-19 pandemic, the SARS-CoV-2 virus has continued to evolve, with new variants outcompeting existing variants and often leading to different dynamics of disease spread. Methods: In this paper, we performed a re
Externí odkaz:
https://doaj.org/article/7bf6c6b4176b4ee7af3f10c02346694f
Autor:
Nicola J Beesley, Krystyna Cwiklinski, Katherine Allen, Rebecca C Hoyle, Terry W Spithill, E James La Course, Diana J L Williams, Steve Paterson, Jane E Hodgkinson
Publikováno v:
PLoS Pathogens, Vol 19, Iss 1, p e1011081 (2023)
Fasciola hepatica infection is responsible for substantial economic losses in livestock worldwide and poses a threat to human health in endemic areas. The mainstay of control in livestock and the only drug licenced for use in humans is triclabendazol
Externí odkaz:
https://doaj.org/article/47274f3eaf804c1e88d60db0e5999538
Autor:
Lauren J Beesley, Paolo Patelli, Kimberly Kaufeld, Jon Schwenk, Kaitlyn M Martinez, Travis Pitts, Martha Barnard, Ben McMahon, Sara Y Del Valle
Publikováno v:
PLoS ONE, Vol 18, Iss 1, p e0279894 (2023)
The COVID-19 pandemic has highlighted a need for better understanding of countries' vulnerability and resilience to not only pandemics but also disasters, climate change, and other systemic shocks. A comprehensive characterization of vulnerability ca
Externí odkaz:
https://doaj.org/article/a3ad4d8271734835963eeb169ca91008
Autor:
Rupam Bhattacharyya, Ritoban Kundu, Ritwik Bhaduri, Debashree Ray, Lauren J. Beesley, Maxwell Salvatore, Bhramar Mukherjee
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Susceptible-Exposed-Infected-Removed (SEIR)-type epidemiologic models, modeling unascertained infections latently, can predict unreported cases and deaths assuming perfect testing. We apply a method we developed to account for the high false
Externí odkaz:
https://doaj.org/article/6e66c701cd454551b2ea2f3c69c4e4cd