Zobrazeno 1 - 10
of 649
pro vyhledávání: '"J. Banchereau"'
Autor:
Bernard A. Fox, Russell K. Hales, Ahmad A. Tarhini, Jeffrey S. Weber, Antoni Ribas, Charles G. Drake, J. Banchereau
Publikováno v:
Annals of Oncology. 21:1944-1951
Background: USA Food and Drug Administration approval for cancer therapy requires demonstration of patient benefit as a marker of clinical efficacy. Prolonged survival is the gold standard for demonstration of efficacy, but other end points such as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f193814ed8a70ca45ba57398b4d7fb8
https://doi.org/10.1093/annonc/mdq048
https://doi.org/10.1093/annonc/mdq048
Publikováno v:
The Journal of Immunology. 159:3347-3353
During T cell-dependent immune response, germinal center B cells accumulate somatic mutations in their Ig V(D)J genes and give rise to affinity-selected B cells. We tested several culture conditions for triggering somatic mutation in human tonsillar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aef8e6060b42401ec8141e210e704ea7
https://doi.org/10.4049/jimmunol.159.7.3347
https://doi.org/10.4049/jimmunol.159.7.3347
Autor:
Catherine Massacrier, Isabelle Durand, Antonio Lanzavecchia, J Banchereau, Marina Cella, Christophe Caux, Béatrice Vanbervliet, Bertrand Dubois
Publikováno v:
Blood. 90:1458-1470
In response to granulocyte-macrophage colony-stimulating factor plus tumor necrosis factor α, cord blood CD34+ hematopoietic progenitor cells differentiate along two unrelated dendritic cell (DC) pathways: (1) the Langerhans cells (LCs), which are c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae3c45d74e9b69f1ae5bec0a0f881c47
https://doi.org/10.1182/blood.v90.4.1458.1458_1458_1470
https://doi.org/10.1182/blood.v90.4.1458.1458_1458_1470
Publikováno v:
The Journal of Immunology. 156:4107-4113
In response to Ag encounter, B lymphocytes undergo a complex maturation process yielding phenotypically distinct subpopulations that are located in highly organized compartments of secondary lymphoid organs. This study describes the patterns of cytok
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14c1eeafb6e3e421a99f9ae9d26d3940
https://doi.org/10.4049/jimmunol.156.11.4107
https://doi.org/10.4049/jimmunol.156.11.4107
Publikováno v:
The Journal of Immunology. 155:4241-4247
It is now well established that interactions of CD40 on the B cells, along with its ligand (CD40-L) on the T cells, regulate B cell proliferation and differentiation. However, the functional significance of CD40 expression on cells known for most eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa53d010566f1d1b1a5d685f0300b538
https://doi.org/10.4049/jimmunol.155.9.4241
https://doi.org/10.4049/jimmunol.155.9.4241
Publikováno v:
The Journal of Immunology. 155:3645-3652
Rheumatoid synovitis is characterized by an infiltration of mononuclear cells and by the proliferation of synoviocytes. Monocytes and synoviocytes are major producers of cytokines, growth factors, and enzymes that contribute to the rheumatoid arthrit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fee0f7e63de5c091880a12665f0efde
https://doi.org/10.4049/jimmunol.155.7.3645
https://doi.org/10.4049/jimmunol.155.7.3645
Publikováno v:
The Journal of Immunology. 155:3345-3352
Germinal centers constitute microanatomic subunits within secondary follicles where B cells undergo somatic mutations, isotype switch and affinity selection. This allows the generation of memory B cells and plasma cells, whose Igs bind to the eliciti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2db66d91ed01369ad194821d47f2bcf5
https://doi.org/10.4049/jimmunol.155.7.3345
https://doi.org/10.4049/jimmunol.155.7.3345
Publikováno v:
Journal of Clinical Oncology. 34:3074-3074
3074Background: Humanized mice engrafted with tumors enable in vivo investigation of the interactions between the human immune system and human cancer. We have recently found that humanized NOD-sci...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::802c0fb7dd5fe0db1fbc63ef05743577
https://doi.org/10.1200/jco.2016.34.15_suppl.3074
https://doi.org/10.1200/jco.2016.34.15_suppl.3074
Publikováno v:
The Journal of Immunology. 152:1693-1701
Anti-CD3-activated human CD4+ T cell clones were found to induce proliferation of CD10+, CD19+, surface(s) Ig- B cell precursors (BCP) isolated from human fetal bone marrow. The great majority of the B lineage cells recovered in cocultures of BCP and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c19c658649b9d18456dc5285a406ab43
https://doi.org/10.4049/jimmunol.152.4.1693
https://doi.org/10.4049/jimmunol.152.4.1693
Autor:
J M, Munro, A S, Freedman, J C, Aster, J G, Gribben, N C, Lee, K K, Rhynhart, J, Banchereau, L M, Nadler
Publikováno v:
Blood. 83:793-798
The B-lymphocyte/accessory-cell activation antigen B7 (BB1) has been shown in vitro to stimulate T-lymphocyte proliferation and cytokine production via CD28 present on the latter cells. In this study, benign lymphoid tissues, lymphomas, and extralymp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5625734b039b712cc3f7051fec93ea8
https://doi.org/10.1182/blood.v83.3.793.bloodjournal833793
https://doi.org/10.1182/blood.v83.3.793.bloodjournal833793