Zobrazeno 1 - 10
of 23
pro vyhledávání: '"J. B. Ulmer"'
Publikováno v:
Journal of Drug Targeting. 11:481-488
The discovery that genes can be functionally transferred from bacteria to mammalian cells has suggested the possible use of bacterial vectors as gene delivery vehicles for vaccines. Attenuated invasive human intestinal bacteria, such as Salmonella an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2498134331956f2c152e7313f0b20e8a
https://doi.org/10.1080/10611860410001670053
https://doi.org/10.1080/10611860410001670053
Publikováno v:
Pharmacology & Therapeutics. 74:195-205
In just a few years, injection of plasmid DNA to elicit immune responses in vivo has developed from an interesting observation to a viable vaccine strategy. DNA vaccines have been shown to elicit both cellular and humoral immune responses and to be e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bddfeef8edd8f4fc29e1664a2f94cac4
https://doi.org/10.1016/s0163-7258(97)82003-7
https://doi.org/10.1016/s0163-7258(97)82003-7
Publikováno v:
Current Opinion in Immunology. 8:531-536
Preclinical DNA vaccine development has continued apace during the past year, with the investigation of several new infectious and non-infectious disease targets as well as advances in our understanding of some of the basic immunologic mechanisms, su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::101d2bd4a7fbabd30431033b4044661d
https://doi.org/10.1016/s0952-7915(96)80042-2
https://doi.org/10.1016/s0952-7915(96)80042-2
Publikováno v:
Methods in molecular medicine. 4
The use of DNA and mRNA as vectors for immunization is a relatively recent development in the field of vaccines. The first paper demonstrating the efficacy of a DNA vaccine in an animal model of viral disease was published in 1993 (1). The rationale
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f4edac515415375deac262887c2b6bba
https://pubmed.ncbi.nlm.nih.gov/21359711
https://pubmed.ncbi.nlm.nih.gov/21359711
Autor:
J B, Ulmer
Publikováno v:
Current opinion in drug discoverydevelopment. 4(2)
DNA vaccines have been extensively studied in the past ten years and much is now known about their effectiveness and mode of action in animal models. Several DNA vaccines have been tested in phase I clinical trials, with mixed results. That is, DNA v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9a6bab321c24032a773ca2f9c49d6e66
https://pubmed.ncbi.nlm.nih.gov/11378958
https://pubmed.ncbi.nlm.nih.gov/11378958
Autor:
A Y, Lee, W C, Manning, C L, Arian, N K, Polakos, J L, Barajas, J B, Ulmer, M, Houghton, X, Paliard
Publikováno v:
Hepatology (Baltimore, Md.). 31(6)
The immunology of hepatitis C virus (HCV) infection should be studied in the context of HCV antigen expression in the liver, because HCV primarily infects this organ. Indeed, the nature, function, and fate of T cells primed after antigen expression i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f216ead5c4135c4e7743f5188b08f4d9
https://pubmed.ncbi.nlm.nih.gov/10827159
https://pubmed.ncbi.nlm.nih.gov/10827159
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 162(7)
Intramuscular injection of BALB/c mice with a DNA plasmid encoding nucleoprotein (NP) from influenza virus A/PR/8/34 (H1N1) provides cross-strain protection against lethal challenge with influenza virus A/HK/68 (H3N2). CTL specific for the H-2Kd-rest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b93794b4316d2fb46f78ce2b5eb3a345
https://pubmed.ncbi.nlm.nih.gov/10201942
https://pubmed.ncbi.nlm.nih.gov/10201942
Publikováno v:
Advances in experimental medicine and biology. 452
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::783392e341c06c7d7734b55296651765
https://pubmed.ncbi.nlm.nih.gov/9889973
https://pubmed.ncbi.nlm.nih.gov/9889973
Publikováno v:
Vaccines ISBN: 9783642641961
DNA vaccination is a novel vaccine technology that is being developed for a variety of clinical applications, as well as being utilized as a tool for exploring basic questions related to antigen processing and presentation. DNA vaccines differ from t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::440f6701657d28c3606a8e524a0fcf25
https://doi.org/10.1007/978-3-642-59955-2_3
https://doi.org/10.1007/978-3-642-59955-2_3
Publikováno v:
Developments in biological standardization. 95
Immunization with plasmid DNA encoding antigenic proteins elicits both antibody and cell-mediated immune responses. This method of producing the protein antigens of interest directly in host cells can provide appropriate tertiary structure for the in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::427b00dafab5dcf1a0a568773593ed7a
https://pubmed.ncbi.nlm.nih.gov/9855413
https://pubmed.ncbi.nlm.nih.gov/9855413