Zobrazeno 1 - 10
of 44
pro vyhledávání: '"J. B. C. Findlay"'
Publikováno v:
Hormone and Metabolic Research. 38:269-278
Retinol (vitamin A) is an example of a small molecule that is essential for higher organisms; its utilisation has been involved in the evolution of a number of proteins. In mammalian species, retinol is obtained from the diet and controls the release
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :3227-3231
The synthesis and reactivity of fully protected thioamide analogues of asparagine and glutamine are described. A key feature of the synthetic strategies employed was the ability to perform selective thiations on multiple carbonyl-containing substrate
Publikováno v:
British Journal of Pharmacology. 124:675-684
1. Repeated applications of neurokinin A (NKA) to oocytes injected with 25 ng wild-type hNK2 receptor cRNA caused complete attenuation of second and subsequent NKA-induced responses while analogous experiments using repeated applications of GR64349 a
Publikováno v:
Biophysical Journal. 73(5):2588-2594
Lipid-peptide interactions with the 27-residue peptide of sequence KLEALYILMVLGFFGFFTLGIMLSYIR reconstituted as beta-sheet assemblies in dimyristoylphosphatidylcholine bilayers have been studied by electron spin resonance (ESR) spectroscopy with spin
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 7:715-718
The highly efficient preparation of two optically pure phenylalanine analogues containing p-N-aryl thiobenzamide moieties are described. These amino acids are readily incorporated into peptides via standard solid-phase strategies.
Autor:
Eugene M. Barnes, Patricia A. Calkin, Satoshi Kuroda, Shigemi Norioka, Masanori Mitta, Ikunoshin Kato, Fumio Sakiyama, Heinz Nika, David T. Chow, Daniel Hess, Edward J. Bures, Hamish D. Morrison, Ruedi Aebersold, G. Marius Clore, Angela M. Gronenborn, Bengt Persson, Patrick Argos, Peter James, Andrew C. Cannons, Larry P. Solomonson, Kenneth E. Dombrowski, William E. Moddeman, Stephen E. Wright, Winona C. Barker, David G. George, Subhendra N. Mattagajasingh, Hara P. Misra, Shuan Shian Huang, Jung San Huang, Y. C. Lee, Wolfgang H. Fischer, A. Grey Craig, Philip N. McFadden, Jonathan A. Lind-quist, M. Bartlet-Jones, W. Jeffery, H. F. Hansen, D. J. C. Pappin, Tomas Bergman, Lars Hjelmqvist, Mats Estonius, Hans Jörnvall, Donna S. Dorow, H. Tschesche, V. Knäuper, T. Kleine, P. Reinemer, S. Schnierer, F. Grams, W. Bode, Christopher Southan, Kenneth Fantom, Patric Lavery, J. B. C. Findlay, D. Akrigg, T. K. Attwood, M. J. Beck, A. J. Bleasby, A. C. T. North, D. J. Parry-Smith, D. N. Perkins, A. Aitken, Y. Patel, H. Martin, D. Jones, K. Robinson, J. Madrazo, S. Howell, Tom Yungwirth, Michael Affolter, Lawrence Amankwa, Harold A. Scheraga, Chao -Yuh Yang, Natalia V. Valentinova, Manlan Yang, Zi -Wei Gu, Antonio M. Gotto, Norman J. Dovichi, Karen C. Waldron, Min Chen, Ian Ireland, Akira Omori, Sachiyo Yoshida, Johann Schaller, Stephan Lengweiler, Egon E. Rickli, José Bubis, Julio O. Ortiz, Carolina Möller, Enrique J. Millán, Victoria L. Boyd, MeriLisa Bozzini, Jindong Zhao, Robert J. DeFranco, Pau -Miau Yuan, G. Marc Loudon, Duy Nguyen, Masaharu Kamo, Takao Kawakami, Norifumi Miyatake, Akira Tsugita, Keiji Takamoto, Kazuo Satake, Oliver Bischof, Mirko Hechenberger, Bernd Thiede, Volker Kruft, Brigitte Wittmann-Liebold, Albrecht Otto, Rainer Benndorf, Peter Jungblut, Monika Ühlein, Henning Urlaub, Rita Berhardt, Regine Kraft, Heike Uhlmann, Vita Beckert, Toshifumi Akizawa, Takaaki Ayabe, Motomi Matsukawa, Michiyasu Itoh, Masatoshi Nishi, Hiroshi Sato, Motoharu Seiki, Masanori Yoshioka, Michal Lebl, Viktor Krchňák, Nikolai F. Sepetov, Petr Kočiš, Marcel Pátek, Zuzana Flegelová, Ronald Ferguson, Kit S. Lam, Robert L. Moritz, James Eddes, Hong Ji, Gavin E. Reid, Richard J. Simpson, William Seffens, C. Dale Poulter, Julia M. Dolence, Pamela D. Bond, Kiyoshi Nokihara, Kazuo Ikegaya, Naoki Morita, Takao Ohmura, S. I. Salikhov, N. J. Sagdiev, A. S. Korneev, Behzod Z. Dolimbek, M. Zhouhair Atassi, J. S. Rosenberg, Z. Yun, P. R. Wyde, M. Z. Atassi, Simon J. Gaskell, Kalyan Rao Anumula, David P. Goldenberg, Ettore Appella, Michelle Fiscella, Nicola Zambrano, Stephen J. Ullrich, Kazuyasu Sakaguchi, Hiroshi Sakamoto, Marc S. Lewis, David Lin, W. Edward Mercer, Carl W. Anderson, Marjorie A. Connelly, Hong Zhang, John D. Sipley, Susan P. Lees-Miller, Stephen P. Jackson, Yong-hong Xie, Jun A. Quion, Chao-yuh Yang, W. F. Brandt, H. Alk, R. Bhaskaran, Chin Yu, C. C. Yang, Agnes H. Henschen, Keith Ashman, Matthias Mann, Juan Guevara, Hung Michael Nguyen, Daniel B. Davison, Joel D. Morrisett, Richard N. Perham, Donald A. Marvin, Martyn F. Symmons, Tamsin D. Terry, Z. H. Beg, J. A. Stonik, J. M. Hoeg, H. B. Brewer, Boris M. Gorovits, C. S. Raman, Paul M. Horowtiz
Publikováno v:
Journal of Protein Chemistry. 13:431-512
Publikováno v:
Tetrahedron Letters. 35:4611-4614
An extremely efficient synthesis of optically pure photoactivatable phenylalanine derivative 1 is described. The key step involves a highly diastereoselective alkylation of a chiral glycine equivalent.
Autor:
J. O. Dolly, Jens Rettig, J. N. Keen, J. B. C. Findlay, O. Pongs, D. N. Parcej, V. E. S. Scott
Publikováno v:
Proceedings of the National Academy of Sciences. 91:1637-1641
Voltage-dependent cation channels are large heterooligomeric proteins. Heterologous expression of cDNAs encoding the alpha subunits alone of K+, Na+, or Ca2+ channels produces functional multimeric proteins; however, coexpression of those for the lat
Autor:
J. B. C. Findlay, Teresa K. Attwood
Publikováno v:
"Protein Engineering, Design and Selection". 7:195-203
Recently we reported the design of a discriminating fingerprint for rhodopsin-like G-protein-coupled receptors (GPCRs). The fingerprint encodes the seven putative membrane-spanning motifs and was potently diagnostic of all GPCRs (52 in all) in versio