Výsledky vyhledávání - "J. Aznar-Salatti"

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Concentrates containing factor IX could improve haemostasis under conditions of thrombocytopenia: studies in an in vitro model

Autor: A M Galan, M. R. Hernández, J. Aznar-Salatti, Juan Carlos Reverter, Gines Escolar, J. Bozzo, M. Pino, Antonio Ordinas, M Vinas

Publikováno v: Vox Sanguinis. 82:113-118

Background and Objectives We explored the effect on haemostasis of different factor IX (FIX) concentrates under thrombocytopenic conditions using an in vitro perfusion technique. Materials and Methods A moderate experimental thrombocytopenia (25 000�

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1e848b26e6837221c590a4d4d8b45e27
https://doi.org/10.1046/j.1423-0410.2002.00157.x

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Uremic Medium Disturbs the Hemostatic Balance of Cultured Human Endothelial Cells

Autor: Antonio Ordinas, Mireia Serradell, Gines Escolar, J Aznar-Salatti, Maribel Diaz-Ricart, María J. Zurbano, Aleix Cases, José Lopez-Pedret

Publikováno v: Scopus-Elsevier

SummaryWe have investigated the ability of serum from uremic patients to modify the thrombogenic properties of the endothelium. The effects of uremic medium on the morphology of endothelial cells (ECs), and their resistance to flow was analyzed. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70e5ad0829c8d145230fd52e1fb80e6f
https://doi.org/10.1055/s-0037-1616539

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Assessment of Potential Thrombogenicity of Coagulation Factor IX Concentrates in an in Vitro Model of Human Thrombogenesis

Autor: Gines Escolar, M. Rosa Hernandez, J. Bozzo, Juan Carlos Reverter, Ana M. Galan, J Aznar-Salatti

Publikováno v: Thrombosis Research. 96:383-389

We have investigated the potential use of perfusion techniques in the evaluation of the thrombogenic profile of factor IX concentrates. Blood from healthy donors was anticoagulated with low molecular weight heparin and incubated with one of the follo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b18adec8725bd46d414493f16db8da91
https://doi.org/10.1016/s0049-3848(99)00134-6

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An intermediate-purity factor VIII concentrate supports platelet adhesion under flow conditions

Autor: C Arnau, James G. White, A. Ordinas, M Carretero, Escolar G, Castillo R, J Aznar-Salatti, J García-Barbal

Publikováno v: Haemophilia. 3:14-20

Von Willebrand factor (vWF) binds to platelets and mediates platelet adhesion to subendothelium to support haemostasis. Factor VIII concentrates containing vWF have been recommended for treatment of bleeding episodes in von Willebrand disease (vWD) t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04ca5e9e657b13677dafc4cd60747084
https://doi.org/10.1046/j.1365-2516.1997.00067.x

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Uraemic medium causes endothelial cell dysfunction characterized by an alteration of the properties of its subendothelial matrix

Autor: Aleix Cases, Ricardo Castillo, J Aznar-Salatti, Gines Escolar, Antonio Ordinas, Antón P, G. Gómez-Ortiz, Revert L

Publikováno v: Nephrology Dialysis Transplantation. 10:2199-2204

Uraemic patients suffer from haemorrhagic disorders and accelerated atherosclerosis. To evaluate the possible role of the vessel wall in these haemostatic alterations associated with uraemia, we investigated the effect of a uraemic milieu on human en

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99e6b084daeca834efdae4e74d6a767c
https://doi.org/10.1093/ndt/10.12.2199

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Comparison between Human Umbilical Artery and Rabbit Abdominal Aorta as Substrata for Platelet Adhesion and Platelet Thrombus Formation under Flow Conditions

Autor: J Aznar-Salatti, Antonio Ordinas, Gines Escolar, Eva Bastida, Marta Garrido

Publikováno v: Scopus-Elsevier

Rabbit abdominal aortas and human umbilical arteries are currently used as substrata for the study of platelet adhesion and aggregate formation under flow conditions. Using immunohistochemical and ultrastructural methods, we have analyzed both vessel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27e259ef60e0a67ac393876a0164d7fc
https://doi.org/10.1159/000158898

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Akademický článek

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Thrombin facilitates primary platelet adhesion onto vascular surfaces in the absence of plasma adhesive proteins: studies under flow conditions

Autor: M, Díaz-Ricart, E, Estebanell, M, Lozano, J, Aznar-Salatti, J G, White, A, Ordinas, G, Escolar

Publikováno v: Haematologica. 85(3)

The effect of local and circulating thrombin on platelet adhesion onto vascular surfaces was explored in the absence of plasma adhesive proteins using flow conditions.To study the local effects of thrombin, denuded rabbit aorta segments were incubate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c81e525a32db7f727708fb084e974cef
https://pubmed.ncbi.nlm.nih.gov/10702817

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Hemostasis in patients with severe von Willebrand disease improves after normal platelet transfusion and normalizes with further correction of the plasma defect

Autor: Ricardo Castillo, J. Monteagudo, Juan Carlos Reverter, Antonio Ordinas, J Aznar-Salatti, Gines Escolar

Publikováno v: Scopus-Elsevier

BACKGROUND: A defective hemostatic effect of plasma concentrate infusion in patients with severe von Willebrand disease (vWD) has been ascribed to the absence of platelet von Willebrand factor (vWF) STUDY DESIGN AND METHODS: The role of platelet vWF

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd438b458218a1019b0f4f622b0fe39f
https://pubmed.ncbi.nlm.nih.gov/9280321

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