Zobrazeno 1 - 10
of 2 716
pro vyhledávání: '"J. Azad"'
Autor:
Chris Denning, Andrew P Holmes, Katja Gehmlich, Nguyen T N Vo, Paulus Kirchhof, Jonas Euchner, Amar J Azad, Max J Cumberland
Publikováno v:
F1000Research, Vol 12 (2024)
Animal models have proven integral to broadening our understanding of complex cardiac diseases but have been hampered by significant species-dependent differences in cellular physiology. Human-induced pluripotent stem cell-derived cardiomyocytes (hiP
Externí odkaz:
https://doaj.org/article/5188b66493974968b86ab2bed156276c
Autor:
Chris Denning, Andrew P Holmes, Katja Gehmlich, Nguyen T N Vo, Paulus Kirchhof, Jonas Euchner, Amar J Azad, Max J Cumberland
Publikováno v:
F1000Research, Vol 12 (2023)
Animal models have proven integral to broadening our understanding of complex cardiac diseases but have been hampered by significant species-dependent differences in cellular physiology. Human-induced pluripotent stem cell-derived cardiomyocytes (hiP
Externí odkaz:
https://doaj.org/article/b68b92aa18c34d3196d8b3400e33af08
Autor:
Sophie Broadway-Stringer, He Jiang, Kirsty Wadmore, Charlotte Hooper, Gillian Douglas, Violetta Steeples, Amar J. Azad, Evie Singer, Jasmeet S. Reyat, Frantisek Galatik, Elisabeth Ehler, Pauline Bennett, Jacinta I. Kalisch-Smith, Duncan B. Sparrow, Benjamin Davies, Kristina Djinovic-Carugo, Mathias Gautel, Hugh Watkins, Katja Gehmlich
Publikováno v:
Cells, Vol 12, Iss 5, p 721 (2023)
Pathogenic variants in ACTN2, coding for alpha-actinin 2, are known to be rare causes of Hypertrophic Cardiomyopathy. However, little is known about the underlying disease mechanisms. Adult heterozygous mice carrying the Actn2 p.Met228Thr variant wer
Externí odkaz:
https://doaj.org/article/0ba42ffd89aa445d9501041c0b0f406d
Publikováno v:
Journal of Agricultural and Crop Research. 8:176-186
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::687a3a554c181c202fe74898175d5c89
https://doi.org/10.33495/jacr_v8i9.20.159
https://doi.org/10.33495/jacr_v8i9.20.159
Autor:
Amar J. Azad, He Jiang, Charlotte Hooper, Sophie Broadway-Stringer, Violetta Steeples, Benjamin Davies, Hugh Watkins, Katja Gehmlich
Publikováno v:
Journal of Molecular and Cellular Cardiology. 173:16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72a3a8b74065b303e80932eeb45b9cb7
https://doi.org/10.1016/j.yjmcc.2022.08.033
https://doi.org/10.1016/j.yjmcc.2022.08.033
Autor:
Garry Meakin, R Ellis, Jennifer White, Hywel C Williams, Kim S Thomas, Rachel H. Haines, John R. Ingram, Andrew Wright, A Perways, Anthony Bewley, J. M. R. Goulding, J Azad, H Hamad, Jonathan M. Batchelor, Alan A Montgomery, Miriam Santer, Nick J. Levell, A Makrygeorgou, Adam Ferguson, S T Cheung, Shyamal Wahie, M. Ogboli, Wei Tan, Anne Rogers, Joanne R Chalmers, Maxine E Whitton, Jane Ravenscroft, Tracey Sach, Lelia Duley, Viktoria Eleftheriadou, A Rajasekaran, J Stainforth, B. Laguda
Background: Economic evidence for vitiligo treatments is absent. Objectives: To determine the cost-effectiveness of (i) handheld narrowband ultraviolet B (NB-UVB) and (ii) a combination of topical corticosteroid (TCS) and NB-UVB compared with TCS alo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::453264072e4e4a135d3f4fe169fe7960
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 3058, p 3058 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 3058, p 3058 (2021)
The Z-disc acts as a protein-rich structure to tether thin filament in the contractile units, the sarcomeres, of striated muscle cells. Proteins found in the Z-disc are integral for maintaining the architecture of the sarcomere. They also enable it t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f40ee23bcaf1c311f9438eb36d93cb38
https://ora.ox.ac.uk/objects/uuid:4ab75e80-0455-49b3-814a-19c0705e76ab
https://ora.ox.ac.uk/objects/uuid:4ab75e80-0455-49b3-814a-19c0705e76ab
Autor:
Julia Beglov, Henrik Isackson, Elisabeth Ehler, Jacinta I. Kalisch-Smith, Violetta Steeples, Duncan B. Sparrow, Katja Gehmlich, Pauline M. Bennett, Norbert Huebner, Charlotte Hooper, Raphael Heilig, Giannino Patone, Benjamin Davies, Hugh Watkins, Amar J. Azad, He Jiang, Mehroz Ehsan, Lisa Leinhos, Jillian N. Simon, Roman Fischer, Matthew Kelly
Publikováno v:
Basic Research in Cardiology
Titin truncating variants are a well-established cause of cardiomyopathy; however, the role of titin missense variants is less well understood. Here we describe the generation of a mouse model to investigate the underlying disease mechanism of a prev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd9bae3d34d47f484f0c6895019203df
https://doi.org/10.1007/s00395-021-00853-z
https://doi.org/10.1007/s00395-021-00853-z
Autor:
A Makrygeorgou, Viktoria Eleftheriadou, J. M. R. Goulding, Joanne R Chalmers, Hywel C Williams, Jennifer White, J Azad, H Hamad, B. Laguda, Jonathan M. Batchelor, Andrew Wright, Miriam Santer, Garry Meakin, M. Ogboli, J Stainforth, Anthony Bewley, Adam Ferguson, Jane Ravenscroft, Nick J. Levell, John R. Ingram, Perways Akram, R Ellis, A Rajasekaran, Lelia Duley, S T Cheung, Alan A Montgomery, Rachel H. Haines, Anne Rogers, Wei Tan, Kim S Thomas, Shyamal Wahie, Maxine E Whitton, Tracey Sach
Publikováno v:
The British Journal of Dermatology
Background: Evidence for the effectiveness of vitiligo treatments is limited. Objectives: To determine the effectiveness of (i) handheld narrowband UVB (NB-UVB) and (ii) a combination of potent topical corticosteroid (TCS) and NB-UVB, compared with T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c3f669ff46666565357b7dfb94fa7fe
https://pubmed.ncbi.nlm.nih.gov/33523459
https://pubmed.ncbi.nlm.nih.gov/33523459
Publikováno v:
Clinical and experimental dermatologyReferences. 46(1)
Nail involvement is estimated to affect 80-90% of patients with psoriasis at some point in their lives and is often associated with severe disease. Patients with nail involvement experience pain, functional impairment and social stigma, with signific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::714fa72dcebec74a84ac437c6d599c20
https://pubmed.ncbi.nlm.nih.gov/32741010
https://pubmed.ncbi.nlm.nih.gov/32741010