Zobrazeno 1 - 10
of 256
pro vyhledávání: '"J. Axel Zeitler"'
Autor:
Prince Bawuah, Mike Evans, Ard Lura, Daniel J. Farrell, Patrick J. Barrie, Peter Kleinebudde, Daniel Markl, J. Axel Zeitler
Publikováno v:
International Journal of Pharmaceutics: X, Vol 5, Iss , Pp 100186- (2023)
Fully automated at-line terahertz time-domain spectroscopy in transmission mode is used to measure tablet porosity for thousands of immediate release tablets. The measurements are rapid and non-destructive. Both laboratory prepared tablets and commer
Externí odkaz:
https://doaj.org/article/8f9989308d494dcf80b7a71bb5279f75
Autor:
Mithushan Soundaranathan, Mohammed Al-Sharabi, Thomas Sweijen, Prince Bawuah, J. Axel Zeitler, S. Majid Hassanizadeh, Kendal Pitt, Blair F. Johnston, Daniel Markl
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 489 (2023)
Pharmaceutical tablet disintegration is a critical process for dissolving and enabling the absorption of the drug substance into the blood stream. The tablet disintegration process consists of multiple connected and interdependent mechanisms: liquid
Externí odkaz:
https://doaj.org/article/5b47c3f334f8441cb2c784533d271611
Autor:
Daniel A. Davis, Jr, Dave A. Miller, Supawan Santitewagun, J. Axel Zeitler, Yongchao Su, Robert O. Williams, III
Publikováno v:
International Journal of Pharmaceutics: X, Vol 3, Iss , Pp 100092- (2021)
We seek to further addresss the questions posed by Moseson et al. regarding whether any residual crystal level, size, or characteristic is acceptable in an amorphous solid dispersion (ASD) such that its stability, enhanced dissolution, and increased
Externí odkaz:
https://doaj.org/article/99a533e6ece349858e1b1e00f0811dc7
Publikováno v:
International Journal of Pharmaceutics: X, Vol 3, Iss , Pp 100079- (2021)
Terahertz time-domain spectroscopy (THz-TDS) is a novel technique which has been applied for pore structure analysis and porosity measurements. For this, mainly the anisotropic Bruggeman (AB-EMA) model is applied to correlate the effective refractive
Externí odkaz:
https://doaj.org/article/c16380a99d854f4b845ddedc0b22aead
Autor:
Sandra Stranzinger, Eva Faulhammer, Jingyi Li, Runqiao Dong, J. Axel Zeitler, Stefano Biserni, Vittorio Calzolari, Johannes G. Khinast, Daniel Markl
Publikováno v:
International Journal of Pharmaceutics: X, Vol 1, Iss , Pp - (2019)
The manufacturing of the majority of solid oral dosage forms is based on the densification of powder. A good understanding of the powder behavior is therefore essential to assure high quality drug products. This is particularly relevant for the capsu
Externí odkaz:
https://doaj.org/article/31ed90cbf5c04c77a32c92e36b1ea008
Autor:
Talia A. Shmool, P.J. Woodhams, Markus Leutzsch, Amberley D. Stephens, Mario U. Gaimann, Michael D. Mantle, Gabriele S. Kaminski Schierle, Christopher F. van der Walle, J. Axel Zeitler
Publikováno v:
International Journal of Pharmaceutics: X, Vol 1, Iss , Pp - (2019)
Characterising the structural dynamics of proteins and the effects of excipients are critical for optimising the design of formulations. In this work we investigated four lyophilised formulations containing bovine serum albumin (BSA) and three formul
Externí odkaz:
https://doaj.org/article/e1faea46313e4533852be0c1c8f39ea7
Autor:
Runqiao Dong, James C. DiNunzio, Brian P. Regler, Walter Wasylaschuk, Adam Socia, J. Axel Zeitler
Publikováno v:
Pharmaceutics, Vol 13, Iss 7, p 933 (2021)
The kinetics of water transport into tablets, and how it can be controlled by the formulation as well as the tablet microstructure, are of central importance in order to design and control the dissolution and drug release process, especially for imme
Externí odkaz:
https://doaj.org/article/38d40c28e5a94f18a86a7ded85730b63
Autor:
Décio Alves-Lima, Jun Song, Xiaoran Li, Alessia Portieri, Yaochun Shen, J. Axel Zeitler, Hungyen Lin
Publikováno v:
Sensors, Vol 20, Iss 5, p 1441 (2020)
Terahertz pulsed imaging (TPI) was introduced approximately fifteen years ago and has attracted a lot of interest in the pharmaceutical industry as a fast, non-destructive modality for quantifying film coatings on pharmaceutical dosage forms. In this
Externí odkaz:
https://doaj.org/article/be3ea378a341431685ad1bb1a012f387
Autor:
Talia A. Shmool, Philippa J. Hooper, Gabriele S. Kaminski Schierle, Christopher F. van der Walle, J. Axel Zeitler
Publikováno v:
Pharmaceutics, Vol 11, Iss 6, p 291 (2019)
Biodegradable poly lactic-co-glycolic acid (PLGA) microspheres can be used to encapsulate peptide and offer a promising drug-delivery vehicle. In this work we investigate the dynamics of PLGA microspheres prepared by freeze-drying and the molecular m
Externí odkaz:
https://doaj.org/article/63b6ff2ff8ad45f9a0cc90403d990138
Publikováno v:
Applied Sciences, Vol 8, Iss 12, p 2700 (2018)
Optical coherence tomography (OCT) has recently attracted a lot of interest in the pharmaceutical manufacturing industry as a fast, contactless and non-destructive modality for quantifying thin film coatings on pharmaceutical dosage forms, which cann
Externí odkaz:
https://doaj.org/article/6fb2d1f581ed4e59bb9b5a8e9f8b9c21