Zobrazeno 1 - 10
of 149
pro vyhledávání: '"J. Autio"'
Autor:
M. Tanvir Rahman, M. Kristian Koski, Joanna Panecka-Hofman, Werner Schmitz, Alexander J. Kastaniotis, Rebecca C. Wade, Rik K. Wierenga, J. Kalervo Hiltunen, Kaija J. Autio
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Mitochondrial fatty acid synthesis (mtFAS) is essential for respiratory function. MtFAS generates the octanoic acid precursor for lipoic acid synthesis, but the role of longer fatty acid products has remained unclear. The structurally well-c
Externí odkaz:
https://doaj.org/article/d16d0b2bf48f43899654c6293ec0c770
Autor:
Aleksi Laajala, Paulus Tokola, Timo J. Autio, Timo Koskenkorva, Mikko Tastula, Pasi Ohtonen, Esa Läärä, Olli-Pekka Alho
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-2 (2023)
Externí odkaz:
https://doaj.org/article/53a787bf424540f6a67870866240b99e
Autor:
Aleksi Laajala, Paulus Tokola, Timo J. Autio, Timo Koskenkorva, Mikko Tastula, Pasi Ohtonen, Esa Läärä, Olli-Pekka Alho
Publikováno v:
Trials, Vol 22, Iss 1, Pp 1-13 (2021)
Abstract Background Tonsillar surgery has been used for decades to treat recurrent and chronic tonsillitis in adults. Recurrent and chronic tonsillitis result in disturbing symptoms, treatment costs, sick leave, and impaired quality of life (QoL). Th
Externí odkaz:
https://doaj.org/article/3572a7d370c94aa68ee210819d296ffa
Autor:
Yasmin ElTahir, Amna Al-Araimi, Remya R. Nair, Kaija J. Autio, Hongmin Tu, Jack C. Leo, Waleed Al-Marzooqi, Eugene H. Johnson
Publikováno v:
BMC Molecular and Cell Biology, Vol 20, Iss 1, Pp 1-12 (2019)
Abstract Background Brucella is a facultative intracellular pathogen responsible for zoonotic disease brucellosis. Little is known about the molecular basis of Brucella adherence to host cells. In the present study, the possible role of Bp26 protein
Externí odkaz:
https://doaj.org/article/0a615cfc184f4bbdba199a707254974c
CoA‐dependent activation of mitochondrial acyl carrier protein links four neurodegenerative diseases
Autor:
Roald A Lambrechts, Hein Schepers, Yi Yu, Marianne van der Zwaag, Kaija J Autio, Marcel A Vieira‐Lara, Barbara M Bakker, Marina A Tijssen, Susan J Hayflick, Nicola A Grzeschik, Ody CM Sibon
Publikováno v:
EMBO Molecular Medicine, Vol 11, Iss 12, Pp 1-21 (2019)
Abstract PKAN, CoPAN, MePAN, and PDH‐E2 deficiency share key phenotypic features but harbor defects in distinct metabolic processes. Selective damage to the globus pallidus occurs in these genetic neurodegenerative diseases, which arise from defect
Externí odkaz:
https://doaj.org/article/d8554242c8ae4af6849ce730ce21786d
Autor:
Timo J. Autio, Timo Atula, Lauri Jouhi, Heikki Irjala, Elina Halme, Anna Jouppila-Mättö, Antti Mäkitie, Petri Koivunen
Publikováno v:
Acta Oto-Laryngologica. 143:334-339
Autor:
Kristiina A. Suominen, Marit Björkstrand, Jukka Ollgren, Tiina J. Autio, Ruska Rimhanen-Finne
Publikováno v:
Infectious Diseases. 55:116-124
Cryptosporidiosis is gastroenteritis caused byWe describe demographics of cryptosporidiosis cases notified to Finnish Infectious Disease Register (FIDR) during a 21-year surveillance period, 1995-2020, and a retrospective investigation of increased c
Autor:
Yasmin ElTahir, Amna Al-Araimi, Remya R. Nair, Kaija J. Autio, Hongmin Tu, Jack C. Leo, Waleed Al-Marzooqi, Eugene H. Johnson
Publikováno v:
BMC Molecular and Cell Biology, Vol 21, Iss 1, Pp 1-1 (2020)
Following publication of the original article [1], an error was reported in the tagging of Eugene H. Johnson and Remya R. Nair in the author group.
Externí odkaz:
https://doaj.org/article/95925607b7f649dc9c463a6103cd8445
Autor:
Kaija J. Autio, Rajaram Venkatesan, F.T. Rahman, J. Alam, M.K. Koski, J.K. Hiltunen, Alexander J. Kastaniotis, Shiv K. Sah-Teli
Publikováno v:
Acta Crystallographica. Section D, Structural Biology
'Acta Crystallographica D ', vol: 77, pages: 840-853 (2021)
'Acta Crystallographica D ', vol: 77, pages: 840-853 (2021)
Rsm22-family proteins are conserved putative SAM-dependent methyltransferases with important functions in mitochondrial translation. Here, the results of a comparative bioinformatics analysis of Rsm22-type proteins are presented, the expression, biop
Publikováno v:
The Neuroscientist. 27:143-158
Fatty acids in mitochondria, in sensu stricto, arise either as β-oxidation substrates imported via the carnitine shuttle or through de novo synthesis by the mitochondrial fatty acid synthesis (mtFAS) pathway. Defects in mtFAS or processes involved i