Zobrazeno 1 - 10
of 83
pro vyhledávání: '"J. Asmar"'
Autor:
Anthony J. Asmar, Shaun R. Abrams, Jenny Hsin, Jason C. Collins, Rita M. Yazejian, Youmei Wu, Jean Cho, Andrew D. Doyle, Samhitha Cinthala, Marleen Simon, Richard H. van Jaarsveld, David B. Beck, Laura Kerosuo, Achim Werner
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract The molecular mechanisms that coordinate patterning of the embryonic ectoderm into spatially distinct lineages to form the nervous system, epidermis, and neural crest-derived craniofacial structures are unclear. Here, biochemical disease-var
Externí odkaz:
https://doaj.org/article/3f2a910eb8564c0e87eee9613f5e8c06
Autor:
Anthony J Asmar, Zackery A Benson, Adele P Peskin, Joe Chalfoun, Mylene Simon, Michael Halter, Anne L Plant
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0298446 (2024)
To facilitate the characterization of unlabeled induced pluripotent stem cells (iPSCs) during culture and expansion, we developed an AI pipeline for nuclear segmentation and mitosis detection from phase contrast images of individual cells within iPSC
Externí odkaz:
https://doaj.org/article/8f8c5e557e5947c2a8f881bcb3391870
Autor:
Anthony J. Asmar, Rita M. Yazejian, Youmei Wu, Jason C. Collins, Jenny Hsin, Jean Cho, Andrew D. Doyle, Samhitha Cinthala, Marleen Simon, Richard H. van Jaarsveld, David B. Beck, Laura Kerosuo, Achim Werner
The molecular mechanisms that coordinate patterning of the embryonic ectoderm into spatially distinct lineages to form the nervous system, epidermis, and craniofacial structures are unclear. Here, biochemical disease-variant profiling reveals a postt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::065fcd290b515775eeaef4e6fc6bee03
https://doi.org/10.1101/2022.09.26.509591
https://doi.org/10.1101/2022.09.26.509591
Autor:
Sarthak Gupta, Amanda K. Ombrello, Emily Rominger, Megan Trick, Karyl S. Barron, Ryan S. Laird, Sinisa Savic, Shuichiro Nakabo, Daniela Ospina Cardona, Ivona Aksentijevich, Carmelo Carmona-Rivera, Gustaf Wigerblad, Mariana J. Kaplan, Emma M. Groarke, Laura W. Dillon, Chyi-Chia Richard Lee, Kalpana Manthiram, Kristina V. Wells, Nicholas Balanda, Zhijie Wu, Helen J. Lachmann, Daniel L. Kastner, Fernanda Gutierrez-Rodrigues, Achim Werner, Michele Nehrebecky, Lisha Xu, Alina Dulau-Florea, Wanxia L. Tsai, Bhavisha A Patel, Stefania Dell'Orso, Weixin Wang, Anthony J. Asmar, Danica Novacic, Katherine R. Calvo, David B. Beck, Robert A. Colbert, Massimo Gadina, William A. Gahl, Wendy Goodspeed, Natalie Deuitch, Dorota Rowczenio, Peter C. Grayson, Daron L. Ross, Sofia Rosenzweig, Anne Jones, Christopher S. Hourigan, James C. Mullikin, Stephen R. Brooks, Jason C. Collins, Wuhong Pei, May Christine V. Malicdan, Neal S. Young, Shawn M. Burgess, Keith A. Sikora, Mones Abu-Asab, Kyle Retterer, Patrycja Hoffmann, Hirotsugu Oda, Marcela A. Ferrada, Zuoming Deng, Benjamin D. Solomon, Jae Jin Chae
Publikováno v:
New England Journal of Medicine. 383:2628-2638
Background Adult-onset inflammatory syndromes often manifest with overlapping clinical features. Variants in ubiquitin-related genes, previously implicated in autoinflammatory disease, may...
Publikováno v:
Néphrologie & Thérapeutique. 18:426
Publikováno v:
Experimental and Molecular Pathology. 106:27-33
Costal cartilage is much understudied compared to the load bearing cartilages. Abnormally grown costal cartilages are associated with the inherited chest wall deformities pectus excavatum and pectus carinatum resulting in sunken or pigeon chest respe
Autor:
Sander Pajusalu, Inga Talvik, Raymond Y. Wang, Daniel L. Kastner, Achim Werner, Mohammed Abul Basar, Precilla D'Souza, Katrin Õunap, Yutaka Nishimura, Johji Inazawa, Ken Saida, Ellen Macnamara, David B. Beck, Anthony J. Asmar, Kristin W. Barañano, Hirotsugu Oda, Marlies Kempers, Weiyi Mu, Naomichi Matsumoto, Joann Bodurtha, Tomoki Kosho, Joyce J. Thompson, Pedro P. Rocha, Ivona Aksentijevich, Apratim Mitra, Magdalena Walkiewicz, Tomoko Tamada, Ryan K. Dale, Satoshi Okada, Daniela Tiaki Uehara, Noriko Miyake, Cynthia J. Tifft
Publikováno v:
Science Advances, 7, 4
Science Advances
Science Advances, 7
Science Advances
Science Advances, 7
Disease-causing mutations in a linkage-specific deubiquitylase provide insights into chromatin remodeling during embryogenesis.
Reversible modification of proteins with linkage-specific ubiquitin chains is critical for intracellular signaling. I
Reversible modification of proteins with linkage-specific ubiquitin chains is critical for intracellular signaling. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::685f6090f52ead44cd34ca0941bfa4a1
https://hdl.handle.net/2066/230561
https://hdl.handle.net/2066/230561
Autor:
David B, Beck, Marcela A, Ferrada, Keith A, Sikora, Amanda K, Ombrello, Jason C, Collins, Wuhong, Pei, Nicholas, Balanda, Daron L, Ross, Daniela, Ospina Cardona, Zhijie, Wu, Bhavisha, Patel, Kalpana, Manthiram, Emma M, Groarke, Fernanda, Gutierrez-Rodrigues, Patrycja, Hoffmann, Sofia, Rosenzweig, Shuichiro, Nakabo, Laura W, Dillon, Christopher S, Hourigan, Wanxia L, Tsai, Sarthak, Gupta, Carmelo, Carmona-Rivera, Anthony J, Asmar, Lisha, Xu, Hirotsugu, Oda, Wendy, Goodspeed, Karyl S, Barron, Michele, Nehrebecky, Anne, Jones, Ryan S, Laird, Natalie, Deuitch, Dorota, Rowczenio, Emily, Rominger, Kristina V, Wells, Chyi-Chia R, Lee, Weixin, Wang, Megan, Trick, James, Mullikin, Gustaf, Wigerblad, Stephen, Brooks, Stefania, Dell'Orso, Zuoming, Deng, Jae J, Chae, Alina, Dulau-Florea, May C V, Malicdan, Danica, Novacic, Robert A, Colbert, Mariana J, Kaplan, Massimo, Gadina, Sinisa, Savic, Helen J, Lachmann, Mones, Abu-Asab, Benjamin D, Solomon, Kyle, Retterer, William A, Gahl, Shawn M, Burgess, Ivona, Aksentijevich, Neal S, Young, Katherine R, Calvo, Achim, Werner, Daniel L, Kastner, Peter C, Grayson
Publikováno v:
Arthritis Rheumatol
Adult-onset inflammatory syndromes often manifest with overlapping clinical features. Variants in ubiquitin-related genes, previously implicated in autoinflammatory disease, may define new disorders.We analyzed peripheral-blood exome sequence data in
Publikováno v:
Experimental cell research. 396(2)
Metazoan development relies on intricate cell differentiation, communication, and migration pathways, which ensure proper formation of specialized cell types, tissues, and organs. These pathways are crucially controlled by ubiquitylation, a reversibl
Autor:
Precilla D'Souza, Anthony J. Asmar, Daniela Tiaki Uehara, Weiyi Mu, Marlies Kempers, Tomoki Kosho, Ryan K. Dale, David B. Beck, Pedro P. Rocha, Cynthia J. Tifft, Naomichi Matsumoto, Ellen Macnamara, Apratim Mitra, Satoshi Okada, Noriko Miyake, Raymond Y. Wang, Ken Saida, Daniel L. Kastner, Magdalena Walkiewicz, Achim Werner, Yutaka Nishimura, Joann Bodurtha, Joyce J. Thompson, Johi Inazawa, Ivona Aksentijevich, Hirotsugu Oda, Mohammed Abul Basar, Kristin W. Barañano
Embryonic development occurs through commitment of pluripotent stem cells to differentiation programs that require highly coordinated changes in gene expression. Chromatin remodeling of gene regulatory elements is a critical component of how such cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0678ea873ddff870447d80f09bd3133
https://doi.org/10.1101/2020.01.23.917450
https://doi.org/10.1101/2020.01.23.917450