Zobrazeno 1 - 10
of 30
pro vyhledávání: '"J. Anthony Thompson"'
Autor:
Mario Vilatobá, Devin E. Eckhoff, Carlton J. Young, José A. Fernández, Cheryl A. Smyth, Christopher Eckstein, Guadalupe Bilbao, J. Anthony Thompson, Sharman E. Ringland, Juan L. Contreras, John H. Griffin
Publikováno v:
Diabetes. 53:2804-2814
Clinical studies indicate that significant loss of functional islet mass occurs in the peritransplant period. Islets are injured as a result of detrimental effects of brain death, pancreas preservation, islet isolation, hypoxia, hyperglycemia, and im
Autor:
David T. Curiel, Firoz G. Rahemtulla, Carlton J. Young, Christopher Eckstein, Devin E. Eckhoff, Guadalupe Bilbao, Juan L. Contreras, Cheryl A. Smyth, Dong Xie, J. Anthony Thompson, Jimmy W. Mays
Publikováno v:
Surgery. 136:537-547
Effective cytoprotection to xenoislets would circumvent the major tissue limitation for pancreatic islet transplantation (PIT). Cell-surface engineering with poly[ethylene glycol] (PEG) derivatives can successfully prevent antibody binding to the sur
Autor:
Carlton J. Young, Mario Vilatobá, Cheryl A. Smyth, Devin E. Eckhoff, Irshad H. Chaudry, Juan L. Contreras, J. Anthony Thompson, Guadalupe Bilbao, Firoz G. Rahemtulla, Christopher Eckstein
Publikováno v:
Surgery. 136:336-345
Background. Current isolation techniques recover only 20% to 50% of the pancreatic islets. Brain death (BI)) is characterized by activation of proinflammatory cytokines (PICs) with reduced islet yields and functionality. We previously reported that 1
Autor:
Devin E. Eckhoff, Christopher Eckstein, Juan L. Contreras, Guadalupe Bilbao, Mario Vilatobá, J. Anthony Thompson
Publikováno v:
Surgery. 136:390-400
Background Ischemia/reperfusion injury (I/R injury) of the liver remains a significant problem during liver surgery and transplantation. I/R injury is associated with liver apoptosis, which is mediated by death receptors such as Fas and tumor necrosi
Autor:
Irshad H. Chaudry, Cheryl A. Smyth, Carlton J. Young, Juan L. Contreras, Mario Vilatobá, Christopher Eckstein, Marty T. Sellers, Devin E. Eckhoff, Guadalupe Bilbao, Firoz G. Rahemtulla, J. Anthony Thompson
Publikováno v:
Diabetes. 52:2935-2942
Although approximately 1 million islets exist in the adult human pancreas, current pancreas preservation and islet isolation techniques recover50%. Presently, cadaveric donors remain the sole source of pancreatic tissue for transplantation. Brain dea
Autor:
Carlton J. Young, Guadalupe Bilbao, Devin E. Eckhoff, Juan L. Contreras, J. Anthony Thompson, Cheryl A. Smyth
Publikováno v:
Transplantation. 74:1252-1259
INTRODUCTION: Proinflammatory cytokines (PIC) (interleukin-1beta, interferon-gamma, and tumor necrosis factor alpha) are released after intraportal islet transplantation lead to functional suppression and islet apoptosis. Estradiol has been shown to
Publikováno v:
Surgery. 132:302-309
Ischemia/reperfusion injury (I/R injury) to the liver can occur in low-flow states associated with trauma and shock and surgical procedures such as liver transplantation. Recent studies have shown that the administration of the female sex hormone 17-
Autor:
Alvaro G. Estévez, Andrés Kamaid, Luis Barbeito, Rafael Radi, J. Anthony Thompson, Trudy L. Cornwell, Joseph S. Beckman
Publikováno v:
Neuroscience Letters. 326:201-205
Deprivation of trophic factors induces expression of neuronal nitric oxide synthase (NOS) and nitric oxide production in cultured motor neurons, leading to apoptosis. Motor neuron apoptosis requires the simultaneous production of nitric oxide and sup
Autor:
Ines Batinic-Haberle, Dale A. Parks, J. Anthony Thompson, Mark T. Gladwin, Thomas M. Ryan, Mutay Aslan, Tim M. Townes, Bruce A. Freeman, Albert Tousson, Brian Adler, C. Roger White, Margaret M. Tarpey, Rakesh P. Patel
Publikováno v:
Proceedings of the National Academy of Sciences. 98:15215-15220
Plasma xanthine oxidase (XO) activity was defined as a source of enhanced vascular superoxide (O \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrs
Autor:
Mark H. Deierhoi, Carlton J. Young, J. Stevenson Bynon, Michael H. Gallichio, Marty T. Sellers, Sharon L. Hudson, J. Anthony Thompson, Devin E. Eckhoff, Arnold G. Diethelm
Publikováno v:
Clinical Transplantation. 14:543-549
Background: Early immunologic and non-immunologic injury of renal allografts adversely affects long-term graft survival. Some degree of preservation injury is inevitable in cadaveric renal transplantation, and, with the reduction in early acute rejec