Zobrazeno 1 - 10
of 18
pro vyhledávání: '"J. Ann Mccay"'
Autor:
Tai L. Guo, Kimber L. White, J. Ann McCay, Dori R. Germolec, Ling X. Zhang, Elizabeth K. Leffel, N. A. Karrow
Publikováno v:
American Journal of Contact Dermatitis. 12:6-17
Background: Although the Murine Local Lymph Node Assay (LLNA) is efficient in identifying chemicals with sensitizing potential, there is increasing need for alternative end points. Cinnamaldehyde (CIN) was chosen for evaluation based on its moderate
Autor:
Robert W. Luebke, Tai L. Guo, Kimber L. White, D. L. Musgrove, Dori R. Germolec, N. A. Karrow, J. Ann McCay, R. D. Brown
Publikováno v:
Drug and Chemical Toxicology. 24:129-149
Bromate is one of the water disinfection by-products (DBPs) produced during the process of ozonation. The purpose of this study was to evaluate the immunotoxic potential of sodium bromate (SB) in female B6C3F1 mice. SB was administered in the drinkin
Autor:
Jennifer S. Parris, Patricia A. Horn, Edwin D. Clark, Katherine Sarlo, J. Ann McCay, Michael K. Robinson, Vanessa L. Peachee, Kimber L. White, Yvonne L. Veloso
Publikováno v:
Toxicological Sciences. 58:299-305
b/d ), a cross of C57Bl/6 (H-2 b ) 3 DBA/2 (H-2 d ) has been used for most of the development work. Preliminary data in the CB6F1(H-2 d/b ), a cross of Balb/c (H-2 d ) 3 C57Bl/6 showed that this strain was similar to the BDF1 in its response to enzym
Autor:
Paal Christian Klykken, Peter C. Mann, Richard W. Mast, Kimber L. White, Dennis J. Naas, Leigh Ann Burns-Naas, J. Ann McCay
Publikováno v:
Toxicological Sciences. 43:28-38
D5 is a low-molecular-weight cyclic siloxane used for industrial and consumer product applications. The objective of the present study was to assess potential toxic and immunomodulatory consequences of inhalation exposure to D5. Male and female Fisch
Autor:
Leigh Ann Burns-Naas, Richard W. Mast, Paal C. Klykken, J. Ann McCay, Kimber L. White, Peter C. Mann, Dennis J. Naas
Publikováno v:
Toxicological Sciences. 43:28-38
Autor:
DAVID G. LEVIER, RONNETTA D. BROWN, DEBORAH L. MUSGROVE, LEON F. BUTTERWORTH, J. ANN MCCAY, KIMBER L. WHITE, LOUIS S. HARRIS, ALBERT E. MUNSON
Publikováno v:
Toxicological Sciences. 24:275-284
Autor:
Felix A. de la Iglesia, Monique M. Fouant, J. Ann Mccay, Kimber L. White, Albert E. Munson, Michael R. Bleavins, Ronald A. Martin
Publikováno v:
Fundamental and Applied Toxicology. 17:723-732
The effect of CI-949, a novel inhibitor of allergic mediator release, on immune function was assessed with holistic mouse models of immunocompetence. Resistance to the bacterial pathogens Listeria monocytogenes and Streptococcus pneumoniae and the B1
Autor:
Leigh Ann Burns-Naas, J. Ann McCay, Mark Zorbas, Kimber L. White, James L Ivett, Stephanie Webber
Publikováno v:
Humanexperimental toxicology. 24(2)
The objective of these investigations was to determine whether exposure to the HIV-1 protease inhibitor nelfinavir compromises immune function in Sprague Dawley rats. Animals (20/sex per group) were exposed orally for 1 or 6 months to nelfinavir at d
Autor:
Tai L. Guo, Kimber L. White, J. Ann McCay, Niel A. Karrow, R.R. Newbold, C. Weis, K.B Delclos, Dori R. Germolec
Publikováno v:
Toxicology. 196(3)
Nonylphenol (NP) has been identified at low levels in surface waters throughout North America. This industrial chemical is primarily used for the production of certain non-ionic surfactants, and has been reported to have weak estrogen-like activity.
Publikováno v:
Toxicology and applied pharmacology. 177(3)
A number of methods have been developed to assess the impact of a xenobiotic on the various components of the immune system. For risk analysis, it is necessary to determine what degree of chemically induced immune perturbation translates into altered