Zobrazeno 1 - 10
of 17
pro vyhledávání: '"J. Andrew Keightley"'
Publikováno v:
Journal of Biological Chemistry. 292:13658-13671
Hemopexin protects against heme toxicity in hemolytic diseases and conditions, sepsis, and sickle cell disease. This protection is sustained by heme-hemopexin complexes in biological fluids that resist oxidative damage during heme-driven inflammation
Publikováno v:
Tetrahedron. 65:1247-1256
Conjugated dendrons based on triphenylene building blocks have been synthesized. Such dendrons exhibit broader absorption wavelength range and higher absorption coefficients than their phenyl analogs. They also possess extended excited state lifetime
Autor:
Sarah L. Dallas, Dinah Lovitch, Cui Chaoying, Nichole T. Huffman, J. Andrew Keightley, Patricia A. Veno, Ronald J. Midura, Jeffrey P. Gorski
Publikováno v:
Journal of Biological Chemistry. 282:26002-26013
Mineral crystal nucleation in UMR 106-01 osteoblastic cultures occurs within 15-25-microm extracellular vesicle-containing biomineralization foci (BMF) structures. We show here that BAG-75 and BSP, biomarkers for these foci, are specifically enriched
Publikováno v:
Molecular & Cellular Proteomics. 3:167-175
We are using a proteomic approach that combines two-dimensional electrophoresis and tandem mass spectrometry to detect and identify proteins that are differentially expressed in a cell line that is resistant to oxidative stress. The resistant cell li
Autor:
Nancy G. Kennaway, J. Andrew Keightley, Neil R. M. Buist, Roberto Anitori, Franklin Quan, Miriam D. Burton
Publikováno v:
The American Journal of Human Genetics. 67(6):1400-1410
We have reinvestigated a young woman, originally reported by us in 1983, who presented with exercise intolerance and lactic acidosis associated with severe deficiency of complex III and who responded to therapy with menadione and ascorbate. Gradually
Autor:
Angels Navarro, J. Andrew Keightley, Mo Rezaiekhaligh, Sherry M Mabry, Ricardo E. Perez, Ikechukwu I. Ekekezie
Publikováno v:
American journal of physiology. Lung cellular and molecular physiology. 296(6)
Acute lung injury involving extremely immature lungs often heals without excessive fibrosis unlike later in gestation and in adults. Several factors may be involved, but fibroblast contraction of collagen has been linked to the level of wound fibrosi
The extracellular adherence protein (Eap) of Staphylococcus aureus participates in a wide range of protein–protein interactions that facilitate the initiation and dissemination of Staphylococcal disease. In this report, we describe the use of a mul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::202e51f0224d602578a28eced5bcde7f
https://europepmc.org/articles/PMC2222813/
https://europepmc.org/articles/PMC2222813/
Publikováno v:
Analytical chemistry. 79(13)
The prevailing method of analyzing tandem-MS data for protein identification involves the comparison of peptide molecular weight and fragmentation data to theoretically predicted values, based on known protein sequences in databases. This is generall
Publikováno v:
Molecularcellular proteomics : MCP. 3(2)
We are using a proteomic approach that combines two-dimensional electrophoresis and tandem mass spectrometry to detect and identify proteins that are differentially expressed in a cell line that is resistant to oxidative stress. The resistant cell li
Site-specific quantitation of protein nitration using liquid chromatography/tandem mass spectrometry
Publikováno v:
Analytical chemistry. 75(10)
The native reference peptide (NRP) method has been adapted to the measure of the degree of protein nitration at a specific tyrosine residue. In these experiments, human serum albumin was modified in a myeloperoxidase-mediated reaction in the presence