Zobrazeno 1 - 10
of 202
pro vyhledávání: '"J. Andrew Bradley"'
Autor:
Irum Amin, Charlotte Rutter, Adam Barlow, Neil K. Russell, J. Andrew Bradley, Andrew Jackson, Andrew J. Butler
Publikováno v:
Journal of Investigative Surgery, Vol 32, Iss 4, Pp 283-289 (2019)
Aim of the study: Intestinal transplantation (IT) is a life-saving procedure for carefully selected patients with intestinal failure. We evaluated patients who had undergone simultaneous intestinal and kidney transplantation (SIKT) to determine wheth
Externí odkaz:
https://doaj.org/article/93a459dc6bce464a971c665c82a809f5
Augmentation of Recipient Adaptive Alloimmunity by Donor Passenger Lymphocytes within the Transplant
Autor:
Ines G. Harper, Jason M. Ali, Simon J.F. Harper, Elizabeth Wlodek, Jawaher Alsughayyir, Margaret C. Negus, M. Saeed Qureshi, Reza Motalleb-Zadeh, Kourosh Saeb-Parsy, Eleanor M. Bolton, J. Andrew Bradley, Menna R. Clatworthy, Thomas M. Conlon, Gavin J. Pettigrew
Publikováno v:
Cell Reports, Vol 15, Iss 6, Pp 1214-1227 (2016)
Chronic rejection of solid organ allografts remains the major cause of transplant failure. Donor-derived tissue-resident lymphocytes are transferred to the recipient during transplantation, but their impact on alloimmunity is unknown. Using mouse car
Externí odkaz:
https://doaj.org/article/07a9ed976d0c42a78866dd7854f9ab85
Autor:
Jason M. Ali, Margaret C. Negus, Thomas M. Conlon, Ines G. Harper, M. Saeed Qureshi, Reza Motallebzadeh, Richard Willis, Kourosh Saeb-Parsy, Eleanor M. Bolton, J. Andrew Bradley, Gavin J. Pettigrew
Publikováno v:
Cell Reports, Vol 14, Iss 5, Pp 1232-1245 (2016)
Summary: MHC alloantigen is recognized by two pathways: “directly,” intact on donor cells, or “indirectly,” as self-restricted allopeptide. The duration of each pathway, and its relative contribution to allograft vasculopathy, remain unclear.
Externí odkaz:
https://doaj.org/article/4d21d09f7ab64d809b676569f934b23c
Autor:
Sarah Tonkin-Crine, PhD, Rishi Pruthi, MBBS, Dominic M. Taylor, MbCHb, Geraldine M. Leydon, PhD, Melania Calestani, PhD, Gabriel C. Oniscu, MD, J. Andrew Bradley, PhD, Charles R. Tomson, DM, Clare Bradley, PhD, Christopher Dudley, MD, Christopher J.E. Watson, MD, Heather Draper, PhD, Rachel J. Johnson, MSc, Wendy Metcalfe, MD, Damian G. Fogarty, MD, Rommel Ravanan, MD, Paul Roderick, MD
Publikováno v:
Transplantation Direct, Vol 4, Iss 5, p e343 (2018)
Background. It is well recognized that there is significant variation between centers in access to kidney transplantation. In the absence of high-grade evidence, it is unclear whether variation is due to patient case mix, other center factors, or ind
Externí odkaz:
https://doaj.org/article/04ca78c52afe45ab8aefffcb7d2247ed
Autor:
Anna J. Dare, Eleanor A. Bolton, Gavin J. Pettigrew, J. Andrew Bradley, Kourosh Saeb-Parsy, Michael P. Murphy
Publikováno v:
Redox Biology, Vol 5, Iss , Pp 163-168 (2015)
Ischemia–reperfusion (IR) injury to the kidney occurs in a range of clinically important scenarios including hypotension, sepsis and in surgical procedures such as cardiac bypass surgery and kidney transplantation, leading to acute kidney injury (A
Externí odkaz:
https://doaj.org/article/b948ee983cd14295ba4d80bc728e4979
Autor:
Charles R.V. Tomson, Rommel Ravanan, John Cairns, Rachel J. Johnson, Diana A. Wu, Matthew Robb, Paul Roderick, Wendy Metcalfe, Clare Bradley, Heather Draper, J. Andrew Bradley, Christopher J.E. Watson, John Forsythe, Christopher Dudley, Gabriel C Oniscu
Publikováno v:
Transplantation. 104:1246-1255
Background Comorbidity is increasingly common in kidney transplant recipients, yet the implications for transplant outcomes are not fully understood. We analyzed the relationship between recipient comorbidity and survival outcomes in a UK-wide prospe
Autor:
Christopher Dudley, Andrea Gibbons, Marco Cinnirella, Rommel Ravanan, Gabriel C Oniscu, Clare Bradley, Rachel J. Johnson, Christopher J.E. Watson, Charles R.V. Tomson, J. Andrew Bradley, Wendy Metcalfe, Heather Draper, Janet Bayfield, Paul Roderick, John Forsythe
Publikováno v:
BMJ Open, Vol 11, Iss 4 (2021)
BMJ Open
Gibbons, A, Bayfield, J, Cinnirella, M, Draper, H, Johnson, R J, Oniscu, G, Ravanan, R, Tomson, C R V, Roderick, P, Metcalfe, W, Forsythe, J L R, Dudley, C, Watson, C J E, Bradley, J A & Bradley, C 2021, ' Changes in quality of life (QoL) and other patient-reported outcome measures (PROMs) in living-donor and deceased-donor kidney transplant recipients and those awaiting transplantation in the UK ATTOM programme: a longitudinal cohort questionnaire survey with additional qualitative interviews. ', BMJ Open . https://doi.org/10.1136/bmjopen-2020-047263
BMJ Open
Gibbons, A, Bayfield, J, Cinnirella, M, Draper, H, Johnson, R J, Oniscu, G, Ravanan, R, Tomson, C R V, Roderick, P, Metcalfe, W, Forsythe, J L R, Dudley, C, Watson, C J E, Bradley, J A & Bradley, C 2021, ' Changes in quality of life (QoL) and other patient-reported outcome measures (PROMs) in living-donor and deceased-donor kidney transplant recipients and those awaiting transplantation in the UK ATTOM programme: a longitudinal cohort questionnaire survey with additional qualitative interviews. ', BMJ Open . https://doi.org/10.1136/bmjopen-2020-047263
ObjectiveTo examine quality of life (QoL) and other patient-reported outcome measures (PROMs) in kidney transplant recipients and those awaiting transplantation.DesignLongitudinal cohort questionnaire surveys and qualitative semi-structured interview
Autor:
Rommel Ravanan, Paul Roderick, J. Andrew Bradley, Christopher J.E. Watson, Rachel J. Johnson, Charles R.V. Tomson, Gabriel C Oniscu, Dominic Taylor, Heather Draper, Geraldine Leydon, Matthew Robb, Damian Fogarty, Wendy Metcalfe, Christopher Dudley, Clare Bradley
Publikováno v:
2019, ' Limited health literacy is associated with reduced access to kidney transplantation ', Kidney International, vol. 95, no. 5, pp. 1244-1252 . https://doi.org/10.1016/j.kint.2018.12.021
Limited health literacy is common in patients with chronic kidney disease (CKD) and has been variably associated with adverse clinical outcomes. The prevalence of limited health literacy is lower in kidney transplant recipients than in individuals st
Publikováno v:
Transplantation Surgery ISBN: 9783030552435
Exciting the imaginations of doctors and patients for millennia, transplantation has struggled to overcome significant technical and biological barriers. Over the course of the last 150 years, physicians have worked in laboratories and operatories to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b135678f2bf52b4d9a0dd0201c1952bd
https://doi.org/10.1007/978-3-030-55244-2_1
https://doi.org/10.1007/978-3-030-55244-2_1
Autor:
Shreya Kulkarni, Kenneth Lim, Dihua Xu, Inez Schoenmakers, Kaido Paapstel, Carmel M. McEniery, Thomas F. Hiemstra, Laurie A. Tomlinson, John Bradley, J. Andrew Bradley, J. Smith, Ian B. Wilkinson
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 7, p e0235082 (2020)
PLoS ONE, Vol 15, Iss 7, p e0235082 (2020)
Kidney donation results in reductions in kidney function and lasting perturbations in phosphate homeostasis, which may lead to adverse cardiovascular sequelae. However, the acute effects of kidney donation on bone mineral parameters including regulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f47730a6d91cbbc1690aa15eb62691d9