Zobrazeno 1 - 5
of 5
pro vyhledávání: '"J. Allen Zhang"'
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 51:947-951
Cationic lipid-mediated drug delivery of small pharmaceutical molecules and biological molecules, such as proteins and DNA, has gained increasing popularity for many in vitro and in vivo applications. For this purpose, 1,2-dioleoyl-3-trimethylammoniu
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 41:582-588
A simple HPLC method was developed for quantification of SN-38, 7-ethyl-10-hydroxycamptothecin, in a novel liposome-based formulation (LE-SN38). The chromatographic separation was achieved on an Agilent Zorbax SB-C18 (4.6 mmx250 mm, 5 microm) analyti
Publikováno v:
International Journal of Pharmaceutics. 270:93-107
SN-38, 7-ethyl-10-hydroxycamptothecin, is the active metabolite of Irinotecan (CPT-11), a topoisomerase I inhibitor commercially available as Camptosar. SN-38 is approximately 200-2000-fold more cytotoxic than CPT-11. Despite its promising anticancer
Autor:
Yasmine Amitay, J. Allen Zhang, Dina Tzemach, Alberto Gabizon, Lidia Mak, Hilary Shmeeda, Kumar Saran, Jenny Gorin, Joerge Ogorka
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 146(1)
Introduction Zoledronic acid (ZOL), a nitrogen-containing bisphosphonate, is a potent inhibitor of farnesyl-pyrophosphate synthase with poor in vitro cytotoxic activity as a result of its limited diffusion into tumor cells. The purpose of this study
Autor:
Lan Ma, Tommaso Sardone, Gopal Anyarambhatla, Imran Ahmad, J. Allen Zhang, Tong Xuan, Sydney Ugwu
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 59(1)
Taxol is a marketed product for the treatment of ovarian, breast, non-small cell lung cancer and AIDS-related Kaposi's Sarcoma. It is thus far one of the most effective anticancer drugs available on the market. However, paclitaxel is only sparingly s