Zobrazeno 1 - 10
of 58
pro vyhledávání: '"J. Alejandro Lopez"'
Autor:
Nicholas L. Dooley, Tinashe G. Chabikwa, Zuleima Pava, Jessica R. Loughland, Julianne Hamelink, Kiana Berry, Dean Andrew, Megan S. F. Soon, Arya SheelaNair, Kim A. Piera, Timothy William, Bridget E. Barber, Matthew J. Grigg, Christian R. Engwerda, J. Alejandro Lopez, Nicholas M. Anstey, Michelle J. Boyle
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract Plasmodium falciparum malaria drives immunoregulatory responses across multiple cell subsets, which protects from immunopathogenesis, but also hampers the development of effective anti-parasitic immunity. Understanding malaria induced tolero
Externí odkaz:
https://doaj.org/article/d4f0ae647bca412fa846c8d4ab492791
Autor:
Yulin Wang, Fabian De Labastida Rivera, Chelsea L. Edwards, Teija C.M. Frame, Jessica A. Engel, Luzia Bukali, Jinrui Na, Susanna S. Ng, Dillon Corvino, Marcela Montes de Oca, Patrick T. Bunn, Megan S.F. Soon, Dean Andrew, Jessica R. Loughland, Jia Zhang, Fiona H. Amante, Bridget E. Barber, James S. McCarthy, J. Alejandro Lopez, Michelle J. Boyle, Christian R. Engwerda
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 19 (2023)
The development of highly effective malaria vaccines and improvement of drug-treatment protocols to boost antiparasitic immunity are critical for malaria elimination. However, the rapid establishment of parasite-specific immune regulatory networks fo
Externí odkaz:
https://doaj.org/article/3c2a3ba4c5594fffbb78ac8fa7298d0d
Autor:
Xue Lu, Yaowu He, Rebecca L. Johnston, Devathri Nanayakarra, Sivanandhini Sankarasubramanian, J. Alejandro Lopez, Michael Friedlander, Murugan Kalimutho, John D. Hooper, Prahlad V. Raninga, Kum Kum Khanna
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-17 (2022)
Abstract Background High-grade serous ovarian carcinomas (HGSCs) are a heterogeneous subtype of epithelial ovarian cancers and include serous cancers arising in the fallopian tube and peritoneum. These cancers are now subdivided into homologous recom
Externí odkaz:
https://doaj.org/article/fc0340ce6f43428181428979968908a9
Autor:
Behnam Rashidieh, Belal Shohayeb, Amanda Louise Bain, Patrick R. J. Fortuna, Debottam Sinha, Andrew Burgess, Richard Mills, Rachael C. Adams, J. Alejandro Lopez, Peter Blumbergs, John Finnie, Murugan Kalimutho, Michael Piper, James Edward Hudson, Dominic C. H. Ng, Kum Kum Khanna
Publikováno v:
PLoS Genetics, Vol 17, Iss 10 (2021)
Homozygous nonsense mutations in CEP55 are associated with several congenital malformations that lead to perinatal lethality suggesting that it plays a critical role in regulation of embryonic development. CEP55 has previously been studied as a cruci
Externí odkaz:
https://doaj.org/article/ca113dc23d2f42909600bf1b070bc7e6
Autor:
Rachael Y. M. Ryan, Jamie Seymour, Alex Loukas, J. Alejandro Lopez, Maria P. Ikonomopoulou, John J. Miles
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Venoms are complex mixtures of toxic compounds delivered by bite or sting. In humans, the consequences of envenomation range from self-limiting to lethal. Critical host defence against envenomation comprises innate and adaptive immune strategies targ
Externí odkaz:
https://doaj.org/article/0283ca8fcf964bd0b4f10cb44072ea55
Autor:
Rachael Y. M. Ryan, Viviana P. Lutzky, Volker Herzig, Taylor B. Smallwood, Jeremy Potriquet, Yide Wong, Paul Masci, Martin F. Lavin, Glenn F. King, J. Alejandro Lopez, Maria P. Ikonomopoulou, John J. Miles
Publikováno v:
Toxins, Vol 12, Iss 11, p 674 (2020)
Venoms act with remarkable specificity upon a broad diversity of physiological targets. Venoms are composed of proteins, peptides, and small molecules, providing the foundation for the development of novel therapeutics. This study assessed the effect
Externí odkaz:
https://doaj.org/article/4c8e9527220b430a98472d3e3d68b10c
Autor:
Chanel E. Smart, Brian J. Morrison, Jodi M. Saunus, Ana Cristina Vargas, Patricia Keith, Lynne Reid, Leesa Wockner, Marjan Askarian-Amiri, Debina Sarkar, Peter T. Simpson, Catherine Clarke, Chris W. Schmidt, Brent A. Reynolds, Sunil R. Lakhani, J. Alejandro Lopez
Publikováno v:
PLoS ONE, Vol 8, Iss 7 (2013)
Externí odkaz:
https://doaj.org/article/50137bcb52864532abec0b2bbe3a6aef
Autor:
Isobel P. Taylor, J. Alejandro Lopez
Publikováno v:
Journal of Cancer Research and Clinical Oncology.
Purpose Pancreatic ductal adenocarcinoma (PDAC) remains a common and difficult cancer to treat. Surgical resection and chemotherapy are standard of care and clinical outcomes remain poor. Oncolytic adenoviruses are a unique approach to the treatment
Autor:
Christopher W. Schmidt, Thomas Wölfel, Volker Lennerz, Martina Fatho, J. Alejandro Lopez, Nicholas K. Hayward, Michelle A. Neller, Julie G. Burel, Antonia L. Pritchard
Raw scanned data from ELISpot plate scanning reader (AID ELISpot Reader Classic); data was then processed using the AID ELISpot software to standardise and analyse the spot counts using intensity and size measurements, to provide the final data prese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f580ab641ae6da059c96170d5e577e3
https://doi.org/10.1158/2326-6066.22538444
https://doi.org/10.1158/2326-6066.22538444
Autor:
Christopher W. Schmidt, Thomas Wölfel, Volker Lennerz, Martina Fatho, J. Alejandro Lopez, Nicholas K. Hayward, Michelle A. Neller, Julie G. Burel, Antonia L. Pritchard
The ability to use circulating peripheral blood cells and matched tumor sequencing data as a basis for neoantigen prediction has exciting possibilities for application in the personalized treatment of cancer patients. We have used a high-throughput s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfbb2d7cb09d2956224b78fcf0fbff7d
https://doi.org/10.1158/2326-6066.c.6548780.v1
https://doi.org/10.1158/2326-6066.c.6548780.v1