Zobrazeno 1 - 10
of 461
pro vyhledávání: '"J. Alcaide"'
Autor:
Victoria Morley, Karamjit Singh Dolt, Carlos J. Alcaide-Corral, Tashfeen Walton, Christophe Lucatelli, Tomoji Mashimo, Adriana A. S. Tavares, Tilo Kunath
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Parkinson’s disease (PD) is a neurodegenerative condition with several major hallmarks, including loss of substantia nigra neurons, reduction in striatal dopaminergic function, and formation of α-synuclein-rich Lewy bodies. Mutations in SNCA, enco
Externí odkaz:
https://doaj.org/article/ac877aa1883140ea863b35dd5f13ac63
The effects of caloric restriction on adipose tissue and metabolic health are sex- and age-dependent
Autor:
Karla J Suchacki, Benjamin J Thomas, Yoshiko M Ikushima, Kuan-Chan Chen, Claire Fyfe, Adriana AS Tavares, Richard J Sulston, Andrea Lovdel, Holly J Woodward, Xuan Han, Domenico Mattiucci, Eleanor J Brain, Carlos J Alcaide-Corral, Hiroshi Kobayashi, Gillian A Gray, Phillip D Whitfield, Roland H Stimson, Nicholas M Morton, Alexandra M Johnstone, William P Cawthorn
Publikováno v:
eLife, Vol 12 (2023)
Caloric restriction (CR) reduces the risk of age-related diseases in numerous species, including humans. CR’s metabolic effects, including decreased adiposity and improved insulin sensitivity, are important for its broader health benefits; however,
Externí odkaz:
https://doaj.org/article/b9038b3cadf8461faa31dbc4889698f6
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract 18F-sodium fluoride (18F-NaF) is a positron emission tomography (PET) radiotracer widely used in skeletal imaging and has also been proposed as a biomarker of active calcification in atherosclerosis. Like most PET radiotracers, 18F-NaF is ty
Externí odkaz:
https://doaj.org/article/459e6fe8f7044373ac50b9b594fb0b0c
Autor:
Karla J. Suchacki, Adriana A. S. Tavares, Domenico Mattiucci, Erica L. Scheller, Giorgos Papanastasiou, Calum Gray, Matthew C. Sinton, Lynne E. Ramage, Wendy A. McDougald, Andrea Lovdel, Richard J. Sulston, Benjamin J. Thomas, Bonnie M. Nicholson, Amanda J. Drake, Carlos J. Alcaide-Corral, Diana Said, Antonella Poloni, Saverio Cinti, Gavin J. Macpherson, Marc R. Dweck, Jack P. M. Andrews, Michelle C. Williams, Robert J. Wallace, Edwin J. R. van Beek, Ormond A. MacDougald, Nicholas M. Morton, Roland H. Stimson, William P. Cawthorn
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Bone marrow adipose tissue (BMAT) comprises over 10% of total fat mass but its systemic metabolic role is unclear. Here, the authors show that BMAT glucose uptake is not insulin or cold responsive; however, BMAT basal glucose uptake is higher than in
Externí odkaz:
https://doaj.org/article/1d8037faca4e43bfbbf32bcfca139cb8
Autor:
Antonia E. Schantl, Anja Verhulst, Ellen Neven, Geert J. Behets, Patrick C. D’Haese, Marc Maillard, David Mordasini, Olivier Phan, Michel Burnier, Dany Spaggiari, Laurent A. Decosterd, Mark G. MacAskill, Carlos J. Alcaide-Corral, Adriana A. S. Tavares, David E. Newby, Victoria C. Beindl, Roberto Maj, Anne Labarre, Chrismita Hegde, Bastien Castagner, Mattias E. Ivarsson, Jean-Christophe Leroux
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Cardiovascular calcification is a serious pathology for which effective pharmacological treatments are lacking. Here the authors show that an optimized oligo(ethylene glycol) derivative of inositol phosphate interferes with calcium phosphate crystall
Externí odkaz:
https://doaj.org/article/af7eef951f974f1d9573843564c6bad9
A Systems-Level Analysis of Total-Body PET Data Reveals Complex Skeletal Metabolism Networks in vivo
Autor:
Karla J. Suchacki, Carlos J. Alcaide-Corral, Samah Nimale, Mark G. Macaskill, Roland H. Stimson, Colin Farquharson, Tom C. Freeman, Adriana A. S. Tavares
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Bone is now regarded to be a key regulator of a number of metabolic processes, in addition to the regulation of mineral metabolism. However, our understanding of complex bone metabolic interactions at a systems level remains rudimentary. in vitro mol
Externí odkaz:
https://doaj.org/article/aa570c4a92154ad2864f652b99810e76
Autor:
M. Bosch-Ramírez, L. Sánchez-Guillén, M. J. Alcaide-Quirós, M. M. Aguilar-Martínez, M. Bellón-López, A. López Delgado, F. López-Rodríguez-Arias, A. Muñoz-Duyos, X. Barber-Valles, A. Arroyo
Publikováno v:
TECHNIQUES IN COLOPROCTOLOGY
r-FISABIO. Repositorio Institucional de Producción Científica
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r-FISABIO. Repositorio Institucional de Producción Científica
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Background The aim of the present study was to evaluate the long-term efficacy of percutaneous tibial nerve stimulation (PTNS) for patients with faecal incontinence (FI) refractory to conservative treatment. Secondary aims were to identify predictors
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