Zobrazeno 1 - 10 of 1 651 pro vyhledávání: '"J. Abergel"'
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Akademický článek
Actinium chelation and crystallization in a macromolecular scaffold
Autor: Jennifer N. Wacker, Joshua J. Woods, Peter B. Rupert, Appie Peterson, Marc Allaire, Wayne W. Lukens, Alyssa N. Gaiser, Stefan G. Minasian, Roland K. Strong, Rebecca J. Abergel
Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-8 (2024)
Abstract Targeted alpha therapy (TAT) pairs the specificity of antigen targeting with the lethality of alpha particles to eradicate cancerous cells. Actinium-225 [225Ac; t1/2 = 9.920(3) days] is an alpha-emitting radioisotope driving the next generat
Externí odkaz: https://doaj.org/article/b852e100a7e24175a5eaf16faeb613d7
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2
Akademický článek
In situ beam reduction of Pu(IV) and Bk(IV) as a route to trivalent transuranic coordination complexes with hydroxypyridinone chelators
Autor: Korey P. Carter, Jennifer N. Wacker, Kurt F. Smith, Gauthier J.-P. Deblonde, Liane M. Moreau, Julian A. Rees, Corwin H. Booth, Rebecca J. Abergel
Publikováno v: Journal of Synchrotron Radiation, Vol 29, Iss 2, Pp 315-322 (2022)
The solution-state interactions of plutonium and berkelium with the octadentate chelator 3,4,3-LI(1,2-HOPO) (343-HOPO) were investigated and characterized by X-ray absorption spectroscopy, which revealed in situ reductive decomposition of the tetrava
Externí odkaz: https://doaj.org/article/751334af381145b599e45e43c75d7049
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3
Akademický článek
Development of radiopharmaceuticals for targeted alpha therapy: Where do we stand?
Autor: Roger M. Pallares, Rebecca J. Abergel
Publikováno v: Frontiers in Medicine, Vol 9 (2022)
Targeted alpha therapy is an oncological treatment, where cytotoxic doses of alpha radiation are locally delivered to tumor cells, while the surrounding healthy tissue is minimally affected. This therapeutic strategy relies on radiopharmaceuticals ma
Externí odkaz: https://doaj.org/article/41da74b01e674c46bf35734088546a39
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4
Akademický článek
Toxicogenomic assessment of organ-specific responses following plutonium internal contamination
Autor: Roger M. Pallares, Erin Jarvis, Dahlia D. An, Cindy H. Wu, Polly Y. Chang, Rebecca J. Abergel
Publikováno v: Environmental Advances, Vol 8, Iss , Pp 100245- (2022)
Plutonium is a radioactive element widely used as an energy source and further employed in military applications. Although global stockpiles of plutonium have increased with time, the toxicological profile of this metal has only been partially charac
Externí odkaz: https://doaj.org/article/49b644938c5b45278fa22f3adae47791
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5
Akademický článek
Probing electronic structure in berkelium and californium via an electron microscopy nanosampling approach
Autor: Alexander Müller, Gauthier J.-P. Deblonde, Peter Ercius, Steven E. Zeltmann, Rebecca J. Abergel, Andrew M. Minor
Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-6 (2021)
The obtention and study of actinide elements is challenging due to various factors including their radioactivity and scarcity. Herein, the authors characterize the atomic and electronic structure of Am, Cm, Bk, and Cf compounds using a transmission e
Externí odkaz: https://doaj.org/article/0882a8ae89b3461288aabb5725d66447
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7
Akademický článek
Ultra-selective ligand-driven separation of strategic actinides
Autor: Gauthier J.-P. Deblonde, Abel Ricano, Rebecca J. Abergel
Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Radionuclides are of great importance for fields such as nuclear medicine and waste recycling, but their efficient purification remains a challenge. Here the authors show that an octadentate hydroxypyridinone chelator enables efficient and robust sep
Externí odkaz: https://doaj.org/article/09adf05cbd5943c195e9cc2a17a5d386
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