Sex-specific associations between plasma interleukin-6 and depression in persons with and without HIV

Autor: Kalen J. Petersen, Xiaoying Yu, Mary Clare Masters, Judith D. Lobo, Tina Lu, Scott Letendre, Ronald J. Ellis, J. Allen McCutchan, Erin Sundermann

Publikováno v: Brain, Behavior, & Immunity - Health, Vol 30, Iss , Pp 100644- (2023)

Background: Persons with HIV (PWH) have both more frequent depression and higher levels of plasma inflammatory biomarkers compared to persons without HIV (PWoH). Inflammation and depressive symptoms are linked, including in PWH; however, it is unclea

Externí odkaz: https://doaj.org/article/44782fcca8814338b7d7128611ad2292

Twelve-year neurocognitive decline in HIV is associated with comorbidities, not age: a CHARTER study

Autor: Robert K Heaton, Ronald J Ellis, Bin Tang, Christina M Marra, Leah H Rubin, David B Clifford, J Allen McCutchan, Benjamin B Gelman, Susan Morgello, Donald R Franklin, Scott L Letendre

Publikováno v: Brain : a journal of neurology, vol 146, iss 3
Brain

Modern antiretroviral therapy (ART) has increased longevity of people with HIV and shifted the age distribution of the HIV pandemic upward toward that of the general population. This positive development has also led to concerns about premature and/o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d83f9c2ef34f736d47dcb8ff210d14ba
https://doi.org/10.1093/brain/awac465

Anemia and Erythrocyte Indices are Associated with Neurocognitive Performance Across Multiple Ability Domains in Adults with HIV

Autor: Oluwakemi K. Okwuegbuna, Harpreet Kaur, Iudicello Jennifer, William S. Bush, Ajay Bharti, Anya Umlauf, Ronald J. Ellis, Donald R. Franklin, Robert K. Heaton, J. Allen McCutchan, Asha R. Kallianpur, Scott L. Letendre

Publikováno v: Journal of acquired immune deficiency syndromes (1999).

Anemia is linked to neurocognitive impairment (NCI) in people with HIV (PWH), but its impact within specific ability domains, and in ssdiverse populations with HIV, is uncertain.Participants included 1,339 PWH enrolled in observational HIV cohort stu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dd17c34a7d947bc958febae6ba93ecd
https://pubmed.ncbi.nlm.nih.gov/36580636

Correlates of HIV RNA concentrations in cerebrospinal fluid during antiretroviral therapy: a longitudinal cohort study

Autor: Alessandro Livelli, Florin Vaida, Ronald J Ellis, Qing Ma, Micol Ferrara, David B Clifford, Ann C Collier, Benjamin B Gelman, Christina M Marra, Justin C McArthur, J Allen McCutchan, Susan Morgello, Ned Sacktor, David M Simpson, Igor Grant, Scott L Letendre, Ian Abramson, Muhammad T. Al-Lozi, Sarah L. Archibald, J. Hampton Atkinson, Brookie M. Best, David B. Clifford, Ann C. Collier, Clint Cushman, Matthew S. Dawson, Ronald J. Ellis, Christine Fennema-Notestine, Donald R. Franklin, Benjamin B. Gelman, Eleanor Head, Robert K. Heaton, Trudy Jones, Scott Letendre, Kenneth R. Maravilla, Thomas D. Marcotte, Christina M. Marra, Justin C. McArthur, J. Allen McCutchan, Letty Mintz, Thomas P. Naidich, David M. Simpson, David M. Smith, Keith C. Stegbauer, Cheuk Y. Tang, Mengesha Teshome

Publikováno v: The Lancet HIV. 6:e456-e462

Summary Background Few large projects have evaluated the factors that influence the HIV RNA concentrations (viral load) in cerebrospinal fluid (CSF) during antiretroviral therapy (ART) over time. We aimed to determine the correlates of HIV RNA in CSF

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::40e924dd0091f459e51611aafdd3c7bf
https://doi.org/10.1016/s2352-3018(19)30143-2

Metabolic Risk Factors as Differential Predictors of Profiles of Neurocognitive Impairment Among Older HIV+ and HIV− Adults: An Observational Study

Autor: J. Allen McCutchan, David J. Moore, Jessica L. Montoya, Laura M Campbell, Elizabeth C Pasipanodya, Emily M Paolillo, Scott Letendre, Rowan Saloner, Dilip V. Jeste, Mariam A Hussain, Robert K. Heaton

Publikováno v: Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists, vol 36, iss 2
Arch Clin Neuropsychol

Objective Neurocognitive performance among older persons, including those living with HIV (people living with HIV [PLWH]), exhibits significant heterogeneity, suggesting subpopulations with differing profiles of neurocognitive impairment (NCI). Metab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48e222c2f4d06e4f68810213034b718d
https://doi.org/10.1093/arclin/acz040