Výsledky vyhledávání - "J. A. Sowden"

Akademický článek

Donor and host photoreceptors engage in material transfer following transplantation of post-mitotic photoreceptor precursors

Autor: R. A. Pearson, A. Gonzalez-Cordero, E. L. West, J. R. Ribeiro, N. Aghaizu, D. Goh, R. D. Sampson, A. Georgiadis, P. V. Waldron, Y. Duran, A. Naeem, M. Kloc, E. Cristante, K. Kruczek, K. Warre-Cornish, J. C. Sowden, A. J. Smith, R. R. Ali

Publikováno v: Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)

Transplantation of healthy photoreceptor cells has been shown to rescue blindness. Here, the authors show that rather than donor cells integrating into the host retina, the predominant mechanism underlying this rescue involves exchange of cytoplasmic

Externí odkaz: https://doaj.org/article/b15e33f7b89f4b918a0a570c180b0b86

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Akademický článek

Manipulation of the Recipient Retinal Environment by Ectopic Expression of Neurotrophic Growth Factors Can Improve Transplanted Photoreceptor Integration and Survival

Autor: E. L. West, R. A. Pearson, Y. Duran, A. Gonzalez-Cordero, R. E. Maclaren, A. J. Smith, J. C. Sowden, R. R. Ali

Publikováno v: Cell Transplantation, Vol 21 (2012)

Degeneration of the neural retina is the leading cause of untreatable blindness in the developed world. Stem cell replacement therapy offers a novel strategy for retinal repair. Postmitotic photoreceptor precursors derived from the early postnatal (P

Externí odkaz: https://doaj.org/article/9edac738641e4c0da01e9a8e0eeffbd4

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Akademický článek

Targeted Disruption of Outer Limiting Membrane Junctional Proteins (Crb1 and ZO-1) Increases Integration of Transplanted Photoreceptor Precursors into the Adult Wild-Type and Degenerating Retina

Autor: R. A. Pearson, A. C. Barber, E. L. West, R. E. Maclaren, Y. Duran, J. W. Bainbridge, J. C. Sowden, R. R. Ali

Publikováno v: Cell Transplantation, Vol 19 (2010)

Diseases culminating in photoreceptor loss are a major cause of untreatable blindness. Transplantation of rod photoreceptors is feasible, provided donor cells are at an appropriate stage of development when transplanted. Nevertheless, the proportion

Externí odkaz: https://doaj.org/article/047abcd08ebc43c88c765a4c8e1c2952

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The management of diabetes in adolescents and young adults: a preliminary case study

Autor: R.B. Tattersall, J.J.A. Robinson, J. A. Sowden

Publikováno v: Journal of Clinical Nursing. 4:257-265

Summary • This paper describes one part of a first-stage study concerned with the care received by a group of adolescents and young adults with insulin-dependent diabetes mellitus (IDDM) in one district health authority. • The paper reports findi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67350a0d6505e512831c980f8ee9e261
https://doi.org/10.1111/j.1365-2702.1995.tb00215.x

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Glucose transporters and in vivo glucose uptake in skeletal and cardiac muscle: fasting, insulin stimulation and immunoisolation studies of GLUT1 and GLUT4

Autor: J. A. Sowden, Peter W Clark, David E. James, Donald J. Chisholm, Edward W. Kraegen, Kenneth J. Rodnick, M. B. Halstead

Publikováno v: Biochemical Journal. 295:287-293

Our aim was to study glucose transporters GLUT1 and GLUT4 in relation to in vivo glucose uptake in rat cardiac and skeletal muscle. The levels of both transporters were of a similar order of magnitude in whole muscle tissue (GLUT1/GLUT4 ratio varied

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3a8349443daabdd2f859a7f1407348e
https://doi.org/10.1042/bj2950287

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Dermatology outpatient case-mix survey for all Welsh Trusts, 2007

Autor: G M, Hill, J M, Sowden, R K, Lister, R A, Logan, A Y, Finlay

Publikováno v: The British journal of dermatology. 162(1)

Background In 2006 a U.K. government White Paper recommended making NHS care in England more accessible by shifting services from secondary care into community settings. There is a shortage of contemporary activity data for U.K. dermatology units to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b00873b1681a0dbf14a59f2d87ee9668
https://pubmed.ncbi.nlm.nih.gov/19796179

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