Zobrazeno 1 - 8
of 8
pro vyhledávání: '"J. A. S. McGuigan"'
Publikováno v:
Experimental physiology. 82(3)
Using Mg(2+)-selective macroelectrodes based on the neutral carriers ETH 7025 and ETH 5506, methods were developed to determine accurately the apparent binding constant (Kapp) and purity, and hence the ionized magnesium concentration ([Mg2+]), in Ca(
Autor:
A. Buri, J. A. S. Mcguigan
Publikováno v:
Experimental physiology. 75(6)
Intracellular free magnesium ([Mg2+]i) was measured in isolated ferret papillary muscles using ion-selective microelectrodes filled with the new magnesium sensor ETH 5214. This new sensor, unlike its predecessor ETH 1117, does not react to marked cha
Autor:
O. Bass, J. A. S. McGuigan
Publikováno v:
Basic Research in Cardiology. 70:585-595
The modern view of the mammalian ventricular action potential is that Na-ions are responsible for depolarization, the plateau is maintained by an inward Ca current and repolarization is due to the inactivation of this inward Ca current against a back
Publikováno v:
The Journal of Physiology. 262:15-37
In sheep and calf ventricular bundles, increasing the internal calcium by increasing the frequency of voltage-clamping to plateau range potentials increased the time-independent outward current. This effect was more marked with higher [Ca]o, and was
Autor:
J. A. S. McGuigan, J. F. Lamb
Publikováno v:
The Journal of Physiology. 186:261-283
1. A new perfused preparation of frog's ventricle is described, whose main advantage is that there are short diffusion distances between the cells and the washing fluid. 2. This preparation responds within a few seconds to alterations in sodium, pota
Autor:
J. F. Lamb, J. A. S. McGuigan
Publikováno v:
The Journal of Physiology. 195:283-315
1. The exchanges of potassium and various other substances have been measured in beating frog's ventricles, using both superfused and distended preparations. In both preparations the high fluid flow rates used (1 ml./sec) cleared the ventricular cavi
Autor:
D. A. Bloom, K. F. Gey, H. O. Handwerker, W. Stauffacher, P. Granboulan, M. C. Trachtenberg, Françoise Roch-Ramel, M. Thomasset, L. E. Farhi, M. W. Hess, P. F. Andrès, M. Brunori, J. Schonbach, P. Haab, A. Chinet, P. Scheid, J. Hindley, F. Rioch-Ramel, R. Cogliati, Pier Luigi Parmeggiani, J. Dubochet, B. Sordat, B. Jeanrenaud, Ph. Wacher, J. F. Boudry, P. Kornblith, G. Amiconi, M. Schardt, P. Walter, Lelio Orci, J. A. S. McGuigan, K. H. Winterhalter, M. Chmelarova, C. Kellenberger-van der Kamp, P. Favarger, J. Corthay, H. Brunner, M. Perisic, E. Kawana, H. Stähelin, J. Ferrero, D. Cameron, M. Schreyer, H. P. Krayenbühl, M. Allgöwer, P. H. Burri, C. Ahmad-Zadeh, M. Anabitarte, A. Scholl, M. Cuénod, H. Mehmel, C. G. Honegger, Willy Haefely, M. Staehelin, A. H. Müller, G. Niemeyer, Michel Schorderet, H. Murer, M. A. Monachon, E. R. Weibel, P. Lehky, N. Jotterand, Georges Peters, J. Bitterli, R. W. Briehl, M. Yanagida, T. B. Miller, M. Scherrer, J. Piiper, M. A. Billeter, H. Wacker, M. Touabi, H. P. Schönwetter, M. Robert, W. Rutishauser, I. Burr, C. Weissmann, U. Heinrich, G. Ahmad-Zadeh, L. Balant, A. Gautier, M. Chmelar, R. W. Straub, G. A. Schoenenberger, H. Oetliker, R. E. Meier, M. Ducommun, P. B. Iynedjian, A. Grieder, P. Tuchschmid, Z. Tomori, M. Da Prada, A. P. Somlyo, D. Kolakofsky, P. Portmann, C. Sandri, K. Pfenninger, A. Benakis, Beatrice M. Anner, B. Glasson, J. R. Gautschi, M. Amherdt, L. W. Black, H. Cottier, J. Häuptli, E. Kellenberger, J. GonÇalves, M. Jalfre, J. P. Farber, W. Arczynska, R. Minder, E. Hösli, A. Wettstein, P. C. Churchill, E. Antonini, W. G. Forssmann, E. Stein, H. Lengsfeld, J. Dalderup, Marcel H. Bickel, P. Schiller, J. W. Stucki, M. Shoyab, H. Moor, C. A. Steiner, R. Schindler, H. M. Goodman, W. Marx, L. Hösli, H. Hecker, H. J. Schatzmann, D. R. Held, Th. Bron, C. Franzini, E. Jéquier, D. Tesi, P. Cerretelli, J. S. Kelly, G. Fellay, Jean-Jacques Dreifuss, H. Langemann, K. H. Berneis, H. M. Eppenberger, R. Braun, S. Rous, Alfred Pletscher, J. Séchaud, P. Kalix, K. Akert, Walter Lichtensteiger, P. Jirounek, T. M. Schenker, L. Cueni, A. Zellweger, W. Wehrli, F. Mira-Moser, C. R. Park, M. Dolivo, J. H. Exton, J. C. Schaer, M. Chmouliovsky, R. Schwyzer, G. Haeusler, S. Lazáry, D. D. Joel, Bernard Mach, J. P. von Wartburg, J. Daldrup, P. E. di Prampero, B. Mechler, Willy P. Burkard, G. B. Koelle, B. Siegwart, A. Geelhaar, A. V. Somlyo, A. K. TebĒcis, J. Wyman
Publikováno v:
Experientia. 26:677-696
Autor:
J. Lamb, J. A. S. Mcguigan
Publikováno v:
Nature. 205(976)
THESE experiments were started to test the flux predictions made by Noble1 from his equations used to describe the action potential of Purkinje fibres. The experiments were done on frog ventricle, as this is the most suitable tissue histologically. A