Zobrazeno 1 - 10 of 49 pro vyhledávání: '"J. A. Ruddick"'
2
Consensus workshop on the evaluation of maternal and developmental toxicity work group I report: End points of maternal and developmental toxicity
Autor: D. E. Hill, John M. DeSesso, Frances J. Zeman, J. D. George, Harold Kalter, M. Kenel, J. K. Markham, D. Cozens, J. W. Kille, J. A. Ruddick, Richard G. Skalko, M. C. Henry, E. Marshall Johnson, Alan G. Fantel, P. W. Wier, R. E. Staples, H. Zenick, D. E. Hutchings, Neil Chernoff
Publikováno v: Teratogenesis, Carcinogenesis, and Mutagenesis. 7:307-310
It was concluded that this conference, sponsored by the EPA, has provided an opportunity to state current ideas regarding the utility of data from studies in developmental toxicology and that the deliberations have highlighted the need to consider fu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0db681a497bf378daee1f6cc00949ff7
https://doi.org/10.1002/tcm.1770070311
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3
2,8‐Dihydromirex: A twenty‐eight day sub‐acute toxicity study in the rat
Autor: V. E. Valli, G.C. Becking, J A Ruddick, David C. Villeneuve, Secours, Ih Chu
Publikováno v: Journal of Environmental Science and Health, Part B. 15:87-107
Weanling Sprague‐Dawley rats were randomly assigned to seven groups each containing 5 males and 5 females. The groups were fed diets for 28 days containing the following levels of chemical: group 1, 0; group 2, 0.5 ppm dihydromirex; group 3, 5.0 pp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e744fffc6cd5e2a55f7d4ac47e2f253
https://doi.org/10.1080/03601238009372166
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4
[14C]Ethylenethiourea: Distribution, excretion, and metabolism in pregnant rats
Autor: J A Ruddick, D T Williams, K S Khera, W L Hierlihy
Publikováno v: Teratology. 13:35-39
Following administration of single oral doses of [14C]ethylenethiourea (ETU) to pregnant rats maternal blood maintained peak radioactivity for 2 h, and the radioactivity was dispersed uniformly between the red blood cells and plasma. The level of rad
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c86b68fc60ee8d71f6a0ce731d23df5b
https://doi.org/10.1002/tera.1420130107
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5
FOLATE LEVELS IN FOOD?A COMPARISON OF MICROBIOLOGICAL ASSAY AND RADIOASSAY METHODS FOR MEASURING FOLATE
Autor: J. Vanderstoep, J. E. Ruddick, J. F. Richards
Publikováno v: Journal of Food Science. 43:1238-1241
Concentrations of N5-methyltetrahydrofolic acid (N5 MTHFA) were determined by the radioassay and the L. casei microbiological assay methods. The correlation coefficient for samples analyzed by both methods was 0.93. The radioassay method was found to
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2aa2cd0121e3a6ad987e8e74c513cf3a
https://doi.org/10.1111/j.1365-2621.1978.tb15277.x
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6
A teratological assessment of four trihalomethanes in the rat
Autor: J A Ruddick, V. E. Valli, David C. Villeneuve, Ih Chu
Publikováno v: Journal of Environmental Science and Health, Part B. 18:333-349
Four trihalomethanes were administered by gavage to Sprague-Dawley rats from day 6 to day 15 of gestation. Chloroform (Ch) was administered at levels of 100, 200 and 400 mg/kg and bromoform (Br), bromodichloromethane (BDCM) and chlorodibromomethane (
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4e9065bd1f0bdcf06d76a067082987c
https://doi.org/10.1080/03601238309372373
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7
A teratological evaluation and analysis of fetal tissue levels following administration of tetrachlorobenzene isomers to the rat
Autor: I. Chu, Sam Kacew, V. E. Valli, David C. Villeneuve, Parulekar Mr, J. A. Ruddick
Publikováno v: Teratology. 29:21-27
Three tetrachlorobenzene (TCB) congeners (1,2,3,4-, 1,2,3,5-, and 1,2,4,5-) were administered daily by gavage to pregnant Sprague-Dawley rats at levels of 50, 100, or 200 mg/kg from day 6 through day 15 of gestation. Mothers were sacrificed on day 21
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aef039f641ae9d0efb5d5e726fea4ad1
https://doi.org/10.1002/tera.1420290104
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8
KINETICS OF THERMAL DEGRADATION OF METHYLTETRAHYDROFOLIC ACID
Autor: J. Vanderstoep, J. E. Ruddick, J. F. Richards
Publikováno v: Journal of Food Science. 45:1019-1022
Thermal degradation of N5 methyltetrahydrofolic acid (N5 MTHFA) under various conditions was studied, using a radioassay method to measure N5 MTHFA concentrations. In the presence of an unlimited oxygen supply, the degradation reaction could be descr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::94f11bea363e3f369c0a14bbb982850f
https://doi.org/10.1111/j.1365-2621.1980.tb07502.x
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10
Transition metal–carbon bonds. Part XXI. Methyl derivatives of platinum(II) and platinum(IV) containing dimethylphenylarsine as ligand
Autor: B. L. Shaw, J. D. Ruddick
Publikováno v: J. Chem. Soc. A. :2964-2969
Methylplatinum(II) complexes of the types cis-[PtMe2(AsMe2Ph)2] and trans-[PtXMe(AsMe2Ph)2](X = halogen), and methylplatinum(IV) complexes of the type [PtX4–nMen(AsMe2Ph)2](X = halogen, n= 1–4) are described. The stereochemistries follow from the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d10e869790922515a9f0d5fbd82967ec
https://doi.org/10.1039/j19690002964
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