Zobrazeno 1 - 4
of 4
pro vyhledávání: '"J. A. Onori"'
Autor:
C. G. Miller, J. A. Onori, Deirdre K. Luttrell, Rakesh Kumar, T. M. Hopper, Kevin Hinkle, Jennifer H. Johnson, I. K. Dev, Robert J. Mullin, K. M. Dold, R. E. Dornsife, Anne T. Truesdale, M. Cheung, Renae M. Crosby, Andrea H. Epperly, Jeffery Alan Stafford, L. E. Harrington
Publikováno v:
British Journal of Cancer
During the development of indazolylpyrimidines as novel and potent inhibitors of vascular endothelial growth factor (VEGF) receptor-2 (VEGFR2) tyrosine kinase, we observed that some human tumour xenografts are more sensitive to VEGFR2 kinase inhibito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6238c5e9573828025868a85e954a97da
https://doi.org/10.1038/sj.bjc.6602109
https://doi.org/10.1038/sj.bjc.6602109
Autor:
William C. Clay, Diane M. Ignar, Thomas A. Kost, John L. Andrews, J. A. Onori, Jeremy D. Leray, David L. Emerson, Sam M. Witherspoon, Katherine E. Kilpatrick
Publikováno v:
Clinical and Experimental Metastasis. 16:9-20
Tumor establishment and metastasis are dependent on extracellular matrix proteolysis, tumor cell migration, and angiogenesis. Urokinase plasminogen activator (uPA) and its receptor are essential mediators of these processes. The purpose of this study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b336169e941dec64957d03fc86b6b22
https://doi.org/10.1023/a:1006503816792
https://doi.org/10.1023/a:1006503816792
Autor:
Deirdre K. Luttrell, Teresa M. Hopper, Robert J. Mullin, Anne T. Truesdale, Victoria B. Knick, Amogh Boloor, Tona M. Gilmer, Renae M. Crosby, Laura E. Harrington, Jennifer H. Johnson, J. A. Onori, Rakesh Kumar, Mui Cheung, Ming-Chih Crouthamel, Sharon K. Rudolph, Charles G. Miller, Jeffrey A. Stafford, Andrea H. Epperly
Publikováno v:
Molecular cancer therapeutics. 6(7)
With the development of targeted therapeutics, especially for small-molecule inhibitors, it is important to understand whether the observed in vivo efficacy correlates with the modulation of desired/intended target in vivo. We have developed a small-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20ec639e43b5d2d06eaf4eb209d1ec8f
https://pubmed.ncbi.nlm.nih.gov/17620431
https://pubmed.ncbi.nlm.nih.gov/17620431
Autor:
M. Cheung, C. G. Miller, J. A. Onori, Jeffrey A. Stafford, Rakesh Kumar, T. M. Hopper, Andrea H. Epperly, Tona M. Gilmer, L. E. Harrington
Publikováno v:
Journal of Clinical Oncology. 23:9537-9537
9537 Background: With the development of targeted therapeutics, especially for small molecule inhibitors, it is important to understand whether the observed in vivo efficacy correlates with the mod...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62278c6c8f0fa630caf7b2bde80fdf49
https://doi.org/10.1200/jco.2005.23.16_suppl.9537
https://doi.org/10.1200/jco.2005.23.16_suppl.9537