Zobrazeno 1 - 10
of 879
pro vyhledávání: '"J. A. McCammon"'
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/c13b167505524de1892c62452cf74f4d
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Intrinsically disordered proteins (IDPs) have recently become systems of great interest due to their involvement in modulating many biological processes and their aggregation being implicated in many diseases. Since IDPs do not have a stable, folded
Externí odkaz:
https://doaj.org/article/041b363eb24b47159e33d09dce0947b2
Autor:
Jeffrey T. Mindrebo, Ashay Patel, Woojoo E. Kim, Tony D. Davis, Aochiu Chen, Thomas G. Bartholow, James J. La Clair, J. Andrew McCammon, Joseph P. Noel, Michael D. Burkart
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
The formation of C-C bonds in fatty acid and polyketide biosynthesis depends on β-ketoacyl-acyl carrier protein (ACP) synthases (KSs). Here, the authors present structures of E.coli KSs bound to substrate mimetic bearing ACPs, providing insights int
Externí odkaz:
https://doaj.org/article/8b2f324577e8467b8bb69a969b0ffd83
Autor:
Surl-Hee Ahn, Christian Seitz, Vinícius Wilian D. Cruzeiro, J. Andrew McCammon, Andreas W. Götz
Publikováno v:
Data in Brief, Vol 38, Iss , Pp 107401- (2021)
Cytochrome bd-type quinol oxidase is an important metalloenzyme that allows many bacteria to survive in low oxygen conditions. Since bd oxidase is found in many prokaryotes but not in eukaryotes, it has emerged as a promising bacterial drug target. E
Externí odkaz:
https://doaj.org/article/69afa77f99d341eea2df95ad8f93668a
Autor:
Clarisse G. Ricci, Janice S. Chen, Yinglong Miao, Martin Jinek, Jennifer A. Doudna, J. Andrew McCammon, Giulia Palermo
Publikováno v:
ACS Central Science, Vol 5, Iss 4, Pp 651-662 (2019)
Externí odkaz:
https://doaj.org/article/081cc12949eb4f1ea40fa9fbc42575d1
Autor:
Christopher T Lee, Justin G Laughlin, Nils Angliviel de La Beaumelle, Rommie E Amaro, J Andrew McCammon, Ravi Ramamoorthi, Michael Holst, Padmini Rangamani
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 4, p e1007756 (2020)
Recent advances in electron microscopy have enabled the imaging of single cells in 3D at nanometer length scale resolutions. An uncharted frontier for in silico biology is the ability to simulate cellular processes using these observed geometries. En
Externí odkaz:
https://doaj.org/article/517c7c181edc4062a0f9f0441ddc7cdb
Autor:
Jui-Hung Weng, Wen Ma, Jian Wu, Pallavi Kaila Sharma, Steve Silletti, J. Andrew McCammon, Susan Taylor
Publikováno v:
ACS chemical biology, vol 18, iss 4
Mutations in the human leucine rich repeat protein kinase-2 (LRRK2) create risk factors for Parkinson's disease, and pathological functions of LRRK2 are often correlated with aberrant kinase activity. Past research has focused on developing selective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84461922d0d2ea3d345200228a2c5337
https://escholarship.org/uc/item/9kp29910
https://escholarship.org/uc/item/9kp29910
Publikováno v:
ACS Central Science, Vol 2, Iss 10, Pp 756-763 (2016)
Externí odkaz:
https://doaj.org/article/97e657e0acd8430d803137aa6503b94a
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 120, iss 9
Muscle contraction is performed by arrays of contractile proteins in the sarcomere. Serious heart diseases, such as cardiomyopathy, can often be results of mutations in myosin and actin. Direct characterization of how small changes in the myosin-acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4410efae2b4722f789d3ed16fd00b43b
https://escholarship.org/uc/item/0071k7sb
https://escholarship.org/uc/item/0071k7sb
Autor:
Yohei, Takahashi, Krystal C, Bosmans, Po-Kai, Hsu, Karnelia, Paul, Christian, Seitz, Chung-Yueh, Yeh, Yuh-Shuh, Wang, Dmitry, Yarmolinsky, Maija, Sierla, Triin, Vahisalu, J Andrew, McCammon, Jaakko, Kangasjärvi, Li, Zhang, Hannes, Kollist, Thien, Trac, Julian I, Schroeder
Publikováno v:
Science advances. 8(49)
The continuing rise in the atmospheric carbon dioxide (CO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::65013494d84830c6b687c9d0d076a8d0
https://pubmed.ncbi.nlm.nih.gov/36475789
https://pubmed.ncbi.nlm.nih.gov/36475789