Zobrazeno 1 - 2
of 2
pro vyhledávání: '"J. A. Maasen"'
Publikováno v:
Archives of Physiology and Biochemistry. 106:269-289
The biological effects of insulin are initiated by the binding of insulin to the insulin receptor. Insulin binds to the extracellular domain of the insulin receptor and induces conformational changes in the receptor, leading to autophosphorylation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd44f70b1e67be646b496713bdbedad8
https://doi.org/10.1076/apab.106.4.269.4369
https://doi.org/10.1076/apab.106.4.269.4369
Autor:
J A, Maasen
Publikováno v:
Minerva medica. 99(3)
This review will consider the concept that the development of a mitochondrial dysfunction in adipocytes is an early step in the pathogenesis for type 2 diabetes. Upon expansion of the adipose mass it becomes gradually inflamed and hypoxic. TNF-alpha,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d014f35eff45a5ad533961f3f97a340f
https://pubmed.ncbi.nlm.nih.gov/18497722
https://pubmed.ncbi.nlm.nih.gov/18497722