Zobrazeno 1 - 10
of 183
pro vyhledávání: '"J. A. Ledbetter"'
Autor:
H H, ABEE, T J, BURNETT, R L, CLARK, D M, DAVIS, E D, GUPTON, L C, JOHNSON, J C, LEDBETTER, O D, TEAGUE, A D, WARDEN
Publikováno v:
ORNL. U.S. Atomic Energy Commission.
Publikováno v:
Pediatric Rehabilitation. 2:1-4
Today's society is more litigant in accidental injury occurrences. With many injuries involving children, malpractice suits have resulted in an influx of information and rehabilitation supports. To address the growing need for legal representation in
Publikováno v:
The Journal of Immunology. 159:3211-3219
The function of MHC class II (HLA-DR) Ags in hemopoiesis is not well defined. Here we investigated the effect of anti-HLA-DR mAb H81.9 on human marrow cells. mAb H81.9 inhibited colony formation from purified CD34+ marrow cells in long term culture-i
Publikováno v:
The Journal of Immunology. 157:4390-4398
CD22 is a key accessory molecule for Ag receptor signaling in B cells that becomes tyrosine phosphorylated in the signaling process. CD22 associates with sIg and strongly amplifies sIg-induced signals. During B cell development, CD22 is initially exp
Publikováno v:
The Journal of Immunology. 157:1652-1658
G28-5 sFv-PE40 is a single-chain immunotoxin that is cytotoxic toward malignant B cells expressing CD40. Human monocytes, which also express cell surface CD40, were found to be insensitive to the immunotoxin. Activation of the monocytic cell line THP
Autor:
Niels Ødum, M. Nielsen, A. Svejgaard, N. Borregaard, Paul Gladstone, Carsten Röpke, J. A. Ledbetter
Publikováno v:
Tissue Antigens. 48:127-135
Following a successful immune response against invading microorganisms, the majority of activated T cells is eliminated, while a minor fraction survives as memory T cells. A decline in T lymphocyte growth factors such as interleukin-2 (IL-2) appears
Publikováno v:
The Journal of Immunology. 157:582-588
B7 molecules (CD80 (B7-1) and CD86 (B7-2/B70)) on APCs provide costimulatory signals for T cell proliferation. We previously described the presence of an alternatively spliced form of murine CD80 (previously termed MB7-2 and renamed as B7-1a) that co
Publikováno v:
The Journal of Immunology. 156:1356-1361
Members of the C-C family of chemotactic cytokines promote chemotaxis and adhesion of leukocytes. In this study, we have identified a murine T cell hybrid that expresses receptors to the chemotactic cytokine monocyte chemotactic protein-1 (MCP-1). Th
Publikováno v:
The Journal of Immunology. 155:2175-2184
The phosphotyrosine phosphatase CD45 is expressed on the surface of all leukocytes and is known to play a critical role in the regulation of both T and B cell function. In contrast, relatively little information exists regarding the role of CD45 in t
Publikováno v:
The Journal of Immunology. 154:3180-3193
The CD28 molecule expressed on the surface of T cells plays a pivotal role in transducing costimulatory signals necessary for cell activation. CD28 coligation enhances tyrosine phosphorylation and phosphoinositol 3-kinase association in responsive ce