Zobrazeno 1 - 10
of 46
pro vyhledávání: '"J. A. Krasney"'
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 164:437-442
To examine the role of nitric oxide (NO) on thermoregulation and control of breathing in obesity, awake obese and age-matched lean Zucker (Z) rats underwent a sustained hypoxic challenge. Body temperature (Tb), oxygen consumption (V O(2)) and ventila
Publikováno v:
Obesity Research. 9:407-413
Objective: To determine whether altered central and/or peripheral opioidergic mechanisms contribute to the altered ventilatory response to sustained hypoxia in obese Zucker rats. Research Methods and Procedures: Eight lean (176 ± 8 [SEM] g) and eigh
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 163:1191-1197
To elucidate the role of serotonin in the maintenance of normal breathing and upper airway (UA) patency in obesity, we studied the effects of systemic administration of ritanserin, a serotonin (5-HT) 2A and 2C receptor antagonist, on ventilation (V E
Autor:
Daniel B. Rifkin, G. Silva, H. Nakano, B. Bishop, A. Roberts, J. A. Krasney, David W. Shucard, G. Farkas
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 280:R1190-R1196
When rats, acclimated to an ambient temperature (Ta) of 29°C, are exposed to 10% O2 for 63 h, the circadian rhythms of body temperature (Tb) and level of activity (La) are abolished, Tb falls to a hypothermic nadir followed by a climb to a hyperther
Autor:
Luc E. Gosselin, J. A. Krasney, E. H. Schlenker, Shin-Da Lee, Gaspar A. Farkas, Hitoshi Nakano
Publikováno v:
Scopus-Elsevier
Levels of endogenous opioids are increased in morbidly obese humans and obese rats. Endogenous opioids are important neuromodulators, and are involved in a wide range of functions including ventilatory control. We studied eight lean and eight obese Z
Publikováno v:
Journal of Applied Physiology. 73:2226-2232
Cerebral vasodilation in hypoxia may involve endothelium-derived relaxing factor-nitric oxide. Methylene blue (MB), an in vitro inhibitor of soluble guanylate cyclase, was injected intravenously into six adult ewes instrumented chronically with left
Publikováno v:
Journal of Applied Physiology. 73:2233-2240
Experiments were carried out on decerebrate cats to identify transsynaptic mediators of spontaneous postsynaptic inhibition of bulbar inspiratory and postinspiratory neurons. Somatic membrane potentials were recorded through the central micropipette
Autor:
Gaspar A. Farkas, Andrew D. Ray, Charles Michlin, Toshiyuki Ogasa, J. A. Krasney, Luc E. Gosselin, Ulysses J. Magalang
Publikováno v:
American journal of physiology. Regulatory, integrative and comparative physiology. 293(1)
Obstructive sleep apnea involves intermittent periods of airway occlusions that lead to repetitive oxygen desaturations. Exposure to chronic intermittent hypoxia (IH) in rats increases diurnal blood pressure and alters skeletal muscle physiology. The
Autor:
Charles Michlin, Peter T Ostrow, J. A. Krasney, Daniel I Rifkin, Gaspar A. Farkas, Shin-Da Lee, Andrew D. Ray, Andrew J Roberts
Publikováno v:
Journal of applied physiology (Bethesda, Md. : 1985). 95(1)
Exercise exacerbates acute mountain sickness. In infants and small mammals, hypoxia elicits a decrease in body temperature (Tb) [hypoxic thermal response (HTR)], which may protect against hypoxic tissue damage. We postulated that exercise would count
Autor:
J. A. Krasney, Daniel B. Rifkin, H. Nakano, B. Bishop, G. Silva, Gaspar A. Farkas, A. Salloum, David W. Shucard, A. Roberts
Publikováno v:
American journal of physiology. Regulatory, integrative and comparative physiology. 279(4)
The hypothermic response of rats to only brief (∼2 h) hypoxia has been described previously. The present study analyzes the hypothermic response in rats, as well as level of activity (La), to prolonged (63 h) hypoxia at rat thermoneutral temperatur