Automated recording of home cage activity and temperature of individual rats housed in social groups: The Rodent Big Brother project

Autor: J. Douglas Armstrong, Kathryn Chapman, Lauren Leslie, William S. Redfern, Rowland R. Sillito, Karen K Tse, Amy Keerie, Catherine Vickers, Claire Grant, Natasha A. Karp, J. A. Heward, John C. Pedersen, Agis Chartsias, Victoria Rimmer, David J. Simpson, T.C. Lukins, Stephanie Klein

Publikováno v: Redfern, W S, Tse, K, Grant, C, Keerie, A, Simpson, D J, Pedersen, J C, Rimmer, V, Leslie, L, Klein, S K, Karp, N A, Sillito, R, Chartsias, A, Lukins, T, Heward, J, Vickers, C, Chapman, K, Armstrong, J D & Homberg, J (ed.) 2017, ' Automated recording of home cage activity and temperature of individual rats housed in social groups: The Rodent Big Brother project ', PLoS ONE, vol. 12, no. 9, e0181068, pp. 1-26 . https://doi.org/10.1371/journal.pone.0181068
PLoS ONE, Vol 12, Iss 9, p e0181068 (2017)
PLoS ONE

Measuring the activity and temperature of rats is commonly required in biomedical research. Conventional approaches necessitate single housing, which affects their behavior and wellbeing. We have used a subcutaneous radiofrequency identification (RFI

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d03a5c66a06d7c3d71cca296a3d2625
https://www.pure.ed.ac.uk/ws/files/43688572/journal.pone.0181068_1_.pdf

Molecular cloning of complex chromosomal translocation t(8;14;12)(q24.1;q32.3;q24.1) in a Burkitt lymphoma cell line defines a new gene (BCL7A) with homology to caldesmon

Autor: D. Jadayel, V. J. Zani, E. Nacheva, K. Takasuki, Janet Shipley, Daniel Catovsky, J. M. Heward, Martin J. S. Dyer, N. Asou

Publikováno v: Scopus-Elsevier

Chromosome 12q24.1 is a recurrent breakpoint in high-grade B-cell non- Hodgkin lymphoma (B-NHL). To identify the genes involved at 12q24.1, molecular cloning of a three-way translocation t(8;14;12)(q24.1;q32.3;q24.1) in a Burkitt lymphoma cell line (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14709fe091c42e13276f333f0aae2793
https://doi.org/10.1182/blood.v87.8.3124.bloodjournal8783124

Rodent big brother: Development and validation of a home cage automated behavioural monitoring system for use in repeat-dose toxicity studies in rats

Autor: J. Douglas Armstrong, David Craig, J. A. Heward, Lauren Leslie, T.C. Lukins, Claire Grant, Ben Allison, Will S. Redfern, Catherine Vickers, Kathryn Chapman

Publikováno v: Toxicology Letters. 229:S47-S48

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::10607b20da270a71e8fe7d79e54da422
https://doi.org/10.1016/j.toxlet.2014.06.206

Identifying semi-Invariant Features on Mouse Contours

Autor: J. Douglas Armstrong, Paul A. Crook, J. A. Heward, T.C. Lukins

Publikováno v: BMVC

This paper addresses the problem of reliably fitting an orientated model to video data of laboratory mice assays by specifically locating semi-invariant points on an extracted outline. In the case of mice, the rapid changes in direction and shape oft

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::713bd14dbec7059235603d3c5ab02ed2
https://doi.org/10.5244/c.22.84

A systematic approach to the assessment of known TNF-alpha polymorphisms in Graves' disease

Autor: H Foxall, M J Simmonds, Joanna M. M. Howson, R. Nithiyananthan, Jayne Franklyn, J. M. Heward, S. C. L. Gough

Publikováno v: Genes and immunity. 5(4)

Single-nucleotide polymorphisms (SNPs) within the tumour necrosis factor alpha (TNF-alpha) gene on chromosome 6p21.3 have been associated with many autoimmune diseases; however, results have been conflicting and accurate allele frequencies have never

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::112f5e765fa2571125c2b492c67b48a9
http://ora.ox.ac.uk/objects/uuid:4aa1bdf1-0c1d-47d4-b734-d113cf673cbe